Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library - Wikidata - wikimedia - TriplyDB

Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library

Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library

http://www.wikidata.org/entity/Q30378123

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What is a "DNA-Compatible" Reaction?Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors Achievements, Challenges, and Opportunities in DNA-Encoded Library Research: An Academic Point of View.Hit-Validation Methodologies for Ligands Isolated from DNA-Encoded Chemical Libraries.An Integrated Microfluidic Processor for DNA-Encoded Combinatorial Library Functional Screening Quantitative PCR is a Valuable Tool to Monitor the Performance of DNA-Encoded Chemical Library Selections.Poisson Statistics of Combinatorial Library Sampling Predict False Discovery Rates of Screening.Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening.A DNA-Encoded Library of Chemical Compounds Based on Common Scaffolding Structures Reveals the Impact of Ligand Geometry on Protein Recognition

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P2860

Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library

http://www.wikidata.org/entity/Q30378123

description

2015 nî lūn-bûn

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2015 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2015 թվականի հուլիսին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Discovery, SAR, and X-ray Bind ...... om a Novel DNA-Encoded Library

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Discovery, SAR, and X-ray Bind ...... om a Novel DNA-Encoded Library

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Discovery, SAR, and X-ray Bind ...... om a Novel DNA-Encoded Library

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Discovery, SAR, and X-ray Bind ...... om a Novel DNA-Encoded Library

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Discovery, SAR, and X-ray Bind ...... om a Novel DNA-Encoded Library

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Discovery, SAR, and X-ray Bind ...... om a Novel DNA-Encoded Library

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ACSMEDCHEMLETT.5B00179

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ACS Medicinal Chemistry Letters

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Discovery, SAR, and X-ray Bind ...... om a Novel DNA-Encoded Library

@en

P2093

Alexander L Satz

http://www.w3.org/2001/XMLSchema#string

Arthur Beljean

http://www.w3.org/2001/XMLSchema#string

Barry A Morgan

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Christopher C Arico-Muendel

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Christopher P Davie

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Christopher S Kollmann

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Chun-Wa Chung

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Clare Hobbs

http://www.w3.org/2001/XMLSchema#string

Don Somers

http://www.w3.org/2001/XMLSchema#string

Eric Boursier

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P2860

Design, synthesis and selection of DNA-encoded small-molecule libraries

5-Aryl-4-carboxamide-1,3-oxazoles: potent and selective GSK-3 inhibitors

Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3

Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase

Encoded library technology as a source of hits for the discovery and lead optimization of a potent and selective class of bactericidal direct inhibitors of Mycobacterium tuberculosis InhA

Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin

Structure and function of branched chain aminotransferases

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle

Small-molecule discovery from DNA-encoded chemical libraries.

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919-924

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scholarly article

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10.1021/ACSMEDCHEMLETT.5B00179

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8

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6

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2015-07-21T00:00:00Z

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