Large-scale determination of previously unsolved protein structures using evolutionary information
about
Improved de novo structure prediction in CASP11 by incorporating coevolution information into Rosetta.Residue proximity information and protein model discrimination using saturation-suppressor mutagenesisDetection and sequence/structure mapping of biophysical constraints to protein variation in saturated mutational libraries and protein sequence alignments with a dedicated serverResidue contacts predicted by evolutionary covariance extend the application of ab initio molecular replacement to larger and more challenging protein folds.Why Is There a Glass Ceiling for Threading Based Protein Structure Prediction Methods?A large-scale comparative assessment of methods for residue-residue contact prediction.Potts Hamiltonian models of protein co-variation, free energy landscapes, and evolutionary fitness.Systematic evaluation of CS-Rosetta for membrane protein structure prediction with sparse NOE restraints.Big-data approaches to protein structure prediction.Protein structure determination using metagenome sequence data.Protein structural motifs in prediction and design.Applications of contact predictions to structural biologyStructure of a bd oxidase indicates similar mechanisms for membrane-integrated oxygen reductases.RodA as the missing glycosyltransferase in Bacillus subtilis and antibiotic discovery for the peptidoglycan polymerase pathway.ConKit: a python interface to contact predictions.Toward high-resolution computational design of the structure and function of helical membrane proteinsCrystal structure of the human sterol transporter ABCG5/ABCG8.Protocols for Molecular Modeling with Rosetta3 and RosettaScriptsChirality-induced spin polarization places symmetry constraints on biomolecular interactionsNullSeq: A Tool for Generating Random Coding Sequences with Desired Amino Acid and GC Contents.Protein structure prediction: making AWSEM AWSEM-ER by adding evolutionary restraints.Epistasis in protein evolution.Large-scale identification of coevolution signals across homo-oligomeric protein interfaces by direct coupling analysis.Molecular Mechanisms of Two-Component Signal Transduction.Comparing co-evolution methods and their application to template-free protein structure prediction.The electron's spin and molecular chirality - how are they related and how do they affect life processes?Mutation effects predicted from sequence co-variation.Architectures of Lipid Transport Systems for the Bacterial Outer Membrane.Structure of FIV capsid C-terminal domain demonstrates lentiviral evasion of genetic fragility by coevolved substitutions.Co-evolution techniques are reshaping the way we do structural bioinformatics.Origins of coevolution between residues distant in protein 3D structures.Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.Correlation of fitness landscapes from three orthologous TIM barrels originates from sequence and structure constraints.Observation selection bias in contact prediction and its implications for structural bioinformaticsInterplay between Penicillin-binding proteins and SEDS proteins promotes bacterial cell wall synthesisEnhanced unbiased sampling of protein dynamics using evolutionary coupling information.An information theoretic framework reveals a tunable allosteric network in group II chaperonins.Large-scale structure prediction by improved contact predictions and model quality assessment.Assessment of hard target modeling in CASP12 reveals an emerging role of alignment-based contact prediction methods.Coevolution of Domain Interactions in the Chloroplast TGD1, 2, 3 Lipid Transfer Complex Specific to Brassicaceae and Poaceae Plants.
P2860
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P2860
Large-scale determination of previously unsolved protein structures using evolutionary information
description
2015 nî lūn-bûn
@nan
2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Large-scale determination of p ...... using evolutionary information
@ast
Large-scale determination of p ...... using evolutionary information
@en
type
label
Large-scale determination of p ...... using evolutionary information
@ast
Large-scale determination of p ...... using evolutionary information
@en
prefLabel
Large-scale determination of p ...... using evolutionary information
@ast
Large-scale determination of p ...... using evolutionary information
@en
P2093
P2860
P50
P356
P1433
P1476
Large-scale determination of p ...... using evolutionary information
@en
P2093
David E Kim
Hahnbeom Park
Hetunandan Kamisetty
Lisa Kinch
Yuxing Liao
P2860
P304
P356
10.7554/ELIFE.09248
P407
P577
2015-09-03T00:00:00Z