PA residues in the 2009 H1N1 pandemic influenza virus enhance avian influenza virus polymerase activity in mammalian cells. - Wikidata - wikimedia - TriplyDB

PA residues in the 2009 H1N1 pandemic influenza virus enhance avian influenza virus polymerase activity in mammalian cells.

PA residues in the 2009 H1N1 pandemic influenza virus enhance avian influenza virus polymerase activity in mammalian cells.

http://www.wikidata.org/entity/Q30402549

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One health, multiple challenges: The inter-species transmission of influenza A virus Influenza A virus polymerase is a site for adaptive changes during experimental evolution in bat cells Virus-specific factors associated with zoonotic and pandemic potential.Selection on haemagglutinin imposes a bottleneck during mammalian transmission of reassortant H5N1 influenza viruses Conserved features of the PB2 627 domain impact influenza virus polymerase function and replication Accumulation of human-adapting mutations during circulation of A(H1N1)pdm09 influenza virus in humans in the United Kingdom.Pandemic potential of avian influenza A (H7N9) viruses.Polymerase discordance in novel swine influenza H3N2v constellations is tolerated in swine but not human respiratory epithelial cells Influenza A Virus Protein PA-X Contributes to Viral Growth and Suppression of the Host Antiviral and Immune Responses Identification of Influenza A Virus PB2 Residues Involved in Enhanced Polymerase Activity and Virus Growth in Mammalian Cells at Low Temperatures Viral dominance of reassortants between canine influenza H3N2 and pandemic (2009) H1N1 viruses from a naturally co-infected dog.Characteristic amino acid changes of influenza A(H1N1)pdm09 virus PA protein enhance A(H7N9) viral polymerase activity.Multiple Natural Substitutions in Avian Influenza A Virus PB2 Facilitate Efficient Replication in Human Cells Residues in the PB2 and PA genes contribute to the pathogenicity of avian H7N3 influenza A virus in DBA/2 mice.Pandemic Seasonal H1N1 Reassortants Recovered from Patient Material Display a Phenotype Similar to That of the Seasonal Parent.Reassortment and mutation of the avian influenza virus polymerase PA subunit overcome species barriers Mutations in polymerase genes enhanced the virulence of 2009 pandemic H1N1 influenza virus in mice A comparative study of short linear motif compositions of the influenza A virus ribonucleoproteins Adaptation of avian influenza A virus polymerase in mammals to overcome the host species barrier Use of fractional factorial design to study the compatibility of viral ribonucleoprotein gene segments of human H7N9 virus and circulating human influenza subtypes.Unusual influenza A viruses in bats.Amino acid changes in the influenza A virus PA protein that attenuate avian H5N1 viruses in mammals.Biochemical impact of the host adaptation-associated PB2 E627K mutation on the temperature-dependent RNA synthesis kinetics of influenza A virus polymerase complex Synergistic Effect of S224P and N383D Substitutions in the PA of H5N1 Avian Influenza Virus Contributes to Mammalian Adaptation Identification of combinatorial host-specific signatures with a potential to affect host adaptation in influenza A H1N1 and H3N2 subtypes.Phylodynamics of H1N1/2009 influenza reveals the transition from host adaptation to immune-driven selection.Prevailing PA Mutation K356R in Avian Influenza H9N2 Virus Increases Mammalian Replication and Pathogenicity.Amino acid substitutions V63I or A37S/I61T/V63I/V100A in the PA N-terminal domain increase the virulence of H7N7 influenza A virus.The RNA-dependent RNA polymerase of the influenza A virus.Unstable polymerase-nucleoprotein interaction is not responsible for avian influenza virus polymerase restriction in human cells.Molecular interactions and trafficking of influenza A virus polymerase proteins analyzed by specific monoclonal antibodies.Influenza A Virus PA Antagonizes Interferon-β by Interacting with Interferon Regulatory Factor 3.Computational analysis of the effect of polymerase acidic (PA) gene mutation F35L in the 2009 pandemic influenza A (H1N1) virus on binding aspects of mononucleotides in the endonuclease domain.Mutations in the PA Protein of Avian H5N1 Influenza Viruses Affect Polymerase Activity and Mouse Virulence.Sweep Dynamics (SD) plots: Computational identification of selective sweeps to monitor the adaptation of influenza A viruses.A Single Amino Acid at the Polymerase Acidic Protein Determines the Pathogenicity of Influenza B Viruses.H5N1 influenza A virus PB1-F2 relieves HAX-1-mediated restriction of avian virus polymerase PA in human lung cells.Large-scale sequence analysis reveals novel human-adaptive markers in PB2 segment of seasonal influenza A viruses.Zoonotic Potential of Influenza A Viruses: A Comprehensive Overview

P2860

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P2860

PA residues in the 2009 H1N1 pandemic influenza virus enhance avian influenza virus polymerase activity in mammalian cells.

http://www.wikidata.org/entity/Q30402549

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2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

PA residues in the 2009 H1N1 p ...... e activity in mammalian cells.

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PA residues in the 2009 H1N1 p ...... e activity in mammalian cells.

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PA residues in the 2009 H1N1 p ...... e activity in mammalian cells.

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PA residues in the 2009 H1N1 p ...... e activity in mammalian cells.

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PA residues in the 2009 H1N1 p ...... e activity in mammalian cells.

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PA residues in the 2009 H1N1 p ...... e activity in mammalian cells.

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PA residues in the 2009 H1N1 p ...... e activity in mammalian cells.

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Alice Hamilton

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Baek Kim

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Birgit Bradel-Tretheway

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Emily A Desmet

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Howard E Bussey

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Jonelle L Mattiacio

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Kendra A Bussey

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Toru Takimoto

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P2860

Updating the Accounts: Global Mortality of the 1918-1920 "Spanish" Influenza Pandemic

Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus

The structural basis for an essential subunit interaction in influenza virus RNA polymerase

Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 Subunit

Structural Basis of the Influenza A Virus RNA Polymerase PB2 RNA-binding Domain Containing the Pathogenicity-determinant Lysine 627 Residue

Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site

The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit

Biological and Structural Characterization of a Host-Adapting Amino Acid in Influenza Virus

Emergence of a novel swine-origin influenza A (H1N1) virus in humans

Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans

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7020-7028

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scholarly article

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10.1128/JVI.00522-11

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14

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85

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Stephen Dewhurst

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2011-05-11T00:00:00Z

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51116849

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21561908

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3126589

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