Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis. - Wikidata - wikimedia - TriplyDB

Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis.

Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis.

http://www.wikidata.org/entity/Q30412997

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Emerging evidence for beneficial macrophage functions in atherosclerosis and obesity-induced insulin resistance Animal models of diabetic macrovascular complications: key players in the development of new therapeutic approaches Insulin resistance, hyperglycemia, and atherosclerosis Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance Endoplasmic reticulum stress and atherosclerosis PLRG1 is an essential regulator of cell proliferation and apoptosis during vertebrate development and tissue homeostasis The impact of macrophage insulin resistance on advanced atherosclerotic plaque progression.Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin.Palmitate and insulin synergistically induce IL-6 expression in human monocytes Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis Insulin resistance and pancreatic beta cell failure Insulin resistance and atherosclerosis.Distinct role of FoxO1 in M-CSF- and GM-CSF-differentiated macrophages contributes LPS-mediated IL-10: implication in hyperglycemia.Inflammatory links between obesity and metabolic disease.Decreased IRS2 and TIMP3 expression in monocytes from offspring of type 2 diabetic patients is correlated with insulin resistance and increased intima-media thickness.Homozygosity for an allele encoding deacetylated FoxO1 protects macrophages from cholesterol-induced inflammation without increasing apoptosis.Insulin receptor substrate-1 expression is increased in circulating leukocytes of patients with acute coronary syndrome Uncomplicating the Macrovascular Complications of Diabetes: The 2014 Edwin Bierman Award Lecture Adipose tissue signaling by nuclear receptors in metabolic complications of obesity Vascular complications of diabetes: mechanisms of injury and protective factors Central insulin action regulates peripheral glucose and fat metabolism in mice.Hyperinsulinemia does not change atherosclerosis development in apolipoprotein E null mice.Insulin signalling mechanisms for triacylglycerol storage.Forkhead transcription factors (FoxOs) promote apoptosis of insulin-resistant macrophages during cholesterol-induced endoplasmic reticulum stress.Insulin resistance and endothelial cell dysfunction: studies in mammalian models.Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E-Deficient Mice.Macrophage peroxisome proliferator activated receptor gamma as a therapeutic target to combat Type 2 diabetes.Expanded granulocyte/monocyte compartment in myeloid-specific triple FoxO knockout increases oxidative stress and accelerates atherosclerosis in mice Innate immune activation in obesity.2013 Russell Ross memorial lecture in vascular biology: cellular and molecular mechanisms of diabetes mellitus-accelerated atherosclerosis.NF-κB, inflammation, and metabolic disease.Role and function of macrophages in the metabolic syndrome.Tissue-specific insulin signaling, metabolic syndrome, and cardiovascular disease.Cell-specific insulin resistance: implications for atherosclerosis.Examining the role of insulin in the regulation of cardiovascular health.Insulin resistance and atherosclerosis: convergence between metabolic pathways and inflammatory nodes.Molecular biology of atherosclerosis.Insulin resistance and hyperglycaemia in cardiovascular disease development.Myeloid Cell-Restricted Insulin/IGF-1 Receptor Deficiency Protects against Skin Inflammation.

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Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis.

http://www.wikidata.org/entity/Q30412997

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2006 nî lūn-bûn

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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2006 թվականի ապրիլին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Myeloid lineage cell-restricte ...... mice against atherosclerosis.

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Myeloid lineage cell-restricte ...... mice against atherosclerosis.

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Myeloid lineage cell-restricte ...... mice against atherosclerosis.

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Myeloid lineage cell-restricte ...... mice against atherosclerosis.

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Myeloid lineage cell-restricte ...... mice against atherosclerosis.

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J.CMET.2006.02.010

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Cell Metabolism

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Myeloid lineage cell-restricte ...... mice against atherosclerosis.

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Gökhan S Hotamisligil

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Julia Baumgartl

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Kazuyuki Tobe

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Liza Makowski

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Macrae Linton

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Marcia McDuffie

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Maximilian Scherner

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Sergio Fazio

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Stephanie Baudler

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Takashi Kadowaki

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P2860

Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: evidence for an anti-inflammatory effect?

Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis

Inflammation in atherosclerosis

A genetic map of the mouse suitable for typing intraspecific crosses.

Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes

The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance.

Ribosomal subunit kinase-2 is required for growth factor-stimulated transcription of the c-Fos gene.

Genetic manipulation of the insulin signalling cascade in mice--potential insight into the pathomechanism of type 2 diabetes.

The evolving diabetes burden in the United States.

Increased CD36 protein as a response to defective insulin signaling in macrophages

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247-256

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10.1016/J.CMET.2006.02.010

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4

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3

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Jens C Brüning

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2006-04-01T00:00:00Z

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7198593

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16581002

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atherosclerosis

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4027059

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