about
Immunosenescence and macrophage functional plasticity: dysregulation of macrophage function by age-associated microenvironmental changesIdentification and Characterization of a Small Molecule Inhibitor of Fatty Acid Binding ProteinsPI3Kp110-, Src-, FAK-dependent and DOCK2-independent migration and invasion of CXCL13-stimulated prostate cancer cellsThe fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activitiesRole of leukotriene B4 receptors in the development of atherosclerosis: potential mechanismsMyeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis.Rapid release of cytoplasmic IL-15 from tumor-associated macrophages is an initial and critical event in IL-12-initiated tumor regression.Functional plasticity of macrophages: reversible adaptation to changing microenvironmentsUncoupling lipid metabolism from inflammation through fatty acid binding protein-dependent expression of UCP2.Adenosine 5'-monophosphate-activated protein kinase regulates IL-10-mediated anti-inflammatory signaling pathways in macrophagesReductive metabolism increases the proinflammatory activity of aldehyde phospholipidsTargeting epidermal fatty acid binding protein for treatment of experimental autoimmune encephalomyelitis.Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates Toll-like receptor 4-mediated inflammatory response via FoxO1.MyD88-dependent SHIP1 regulates proinflammatory signaling pathways in dendritic cells after monophosphoryl lipid A stimulation of TLR4.Fatty acids induce leukotriene C4 synthesis in macrophages in a fatty acid binding protein-dependent manner.The role of JAK-3 in regulating TLR-mediated inflammatory cytokine production in innate immune cells.Regulation of Th17 differentiation by epidermal fatty acid-binding protein.AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling.Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype.Functional plasticity of macrophages: in situ reprogramming of tumor-associated macrophages.Macrophage CD40 signaling: a pivotal regulator of disease protection and pathogenesis.Deficiency of AMPK in CD8+ T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell death.Broccoli-Derived Nanoparticle Inhibits Mouse Colitis by Activating Dendritic Cell AMP-Activated Protein Kinase.Adipose Fatty Acid Binding Protein Promotes Saturated Fatty Acid-Induced Macrophage Cell Death through Enhancing Ceramide Production.Trophoblast-derived exosomes mediate monocyte recruitment and differentiation.AMPK-dependent and independent effects of AICAR and compound C on T-cell responses.Anti-apoptotic signalling by the Dot/Icm secretion system of L. pneumophila.Generation of a multimeric form of CD40L with potent immunostimulatory activity using streptavidin as a chaperon.TNF receptor-associated factor 6 is an essential mediator of CD40-activated proinflammatory pathways in monocytes and macrophages.Ectopic expression of protein-tyrosine kinase Bcr-Abl suppresses tumor necrosis factor (TNF)-induced NF-kappa B activation and IkappaBalpha phosphorylation. Relationship with down-regulation of TNF receptors.Ethanol inhibits lipid raft-mediated TCR signaling and IL-2 expression: potential mechanism of alcohol-induced immune suppression.Interaction of adipocyte fatty acid-binding protein (AFABP) and JAK2: AFABP/aP2 as a regulator of JAK2 signaling.Lactobacillus rhamnosus GG reduces hepatic TNFα production and inflammation in chronic alcohol-induced liver injury.The vaccinia virus N1L protein influences cytokine secretion in vitro after infection.Inhibition of methionine adenosyltransferase II induces FasL expression, Fas-DISC formation and caspase-8-dependent apoptotic death in T leukemic cells.CD40-mediated activation of vascular smooth muscle cell chemokine production through a Src-initiated, MAPK-dependent pathway.Deficiency of fatty acid-binding proteins in mice confers protection from development of experimental autoimmune encephalomyelitis.Expression of adipocyte/macrophage fatty acid binding protein in tumor associated macrophages promotes breast cancer progression.Stearic Acid Induces CD11c Expression in Proinflammatory Macrophages via Epidermal Fatty Acid Binding Protein.Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
P50
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P50
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Jill Suttles
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Jill Suttles
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Jill Suttles
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