Deletion of Rab GAP AS160 modifies glucose uptake and GLUT4 translocation in primary skeletal muscles and adipocytes and impairs glucose homeostasis. - Wikidata - wikimedia - TriplyDB

Deletion of Rab GAP AS160 modifies glucose uptake and GLUT4 translocation in primary skeletal muscles and adipocytes and impairs glucose homeostasis.

Deletion of Rab GAP AS160 modifies glucose uptake and GLUT4 translocation in primary skeletal muscles and adipocytes and impairs glucose homeostasis.

http://www.wikidata.org/entity/Q30416318

about

6-Mercaptopurine augments glucose transport activity in skeletal muscle cells in part via a mechanism dependent upon orphan nuclear receptor NR4A3 GLUT4 defects in adipose tissue are early signs of metabolic alterations in Alms1GT/GT, a mouse model for obesity and insulin resistance Acute low-dose endotoxin treatment results in improved whole-body glucose homeostasis in mice.Rab GAPs AS160 and Tbc1d1 play nonredundant roles in the regulation of glucose and energy homeostasis in mice Pannexin 1 is required for full activation of insulin-stimulated glucose uptake in adipocytes.Deletion of the Rab GAP Tbc1d1 modifies glucose, lipid, and energy homeostasis in mice Catecholamine-induced lipolysis causes mTOR complex dissociation and inhibits glucose uptake in adipocytes.Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance.MIF deficiency does not alter glucose homeostasis or adipose tissue inflammatory cell infiltrates during diet-induced obesity In vitro palmitate treatment of myotubes from postmenopausal women leads to ceramide accumulation, inflammation and affected insulin signaling.Gestational protein restriction impairs insulin-regulated glucose transport mechanisms in gastrocnemius muscles of adult male offspring.Expression and phosphorylation of the AS160_v2 splice variant supports GLUT4 activation and the Warburg effect in multiple myeloma.Roles of TBC1D1 and TBC1D4 in insulin- and exercise-stimulated glucose transport of skeletal muscle Zinc-α2-Glycoprotein Modulates AKT-Dependent Insulin Signaling in Human Adipocytes by Activation of the PP2A Phosphatase.Skeletal Muscle Insulin Resistance and Absence of Inflammation Characterize Insulin-Resistant Grade I Obese Women.Activation of G proteins by GIV-GEF is a pivot point for insulin resistance and sensitivity.AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues Enhanced fasting glucose turnover in mice with disrupted action of TUG protein in skeletal muscle.TDP-43, an ALS linked protein, regulates fat deposition and glucose homeostasis.A proteolytic pathway that controls glucose uptake in fat and muscle.Role of Rab GTPases and their interacting proteins in mediating metabolic signalling and regulation.[6]-Gingerol Affects Glucose Metabolism by Dual Regulation via the AMPKα2-Mediated AS160-Rab5 Pathway and AMPK-Mediated Insulin Sensitizing Effects.Challenging of AS160/TBC1D4 Alters Intracellular Lipid milieu in L6 Myotubes Incubated With Palmitate.Diabetes in Population Isolates: Lessons from Greenland.TWEAK prevents TNF-α-induced insulin resistance through PP2A activation in human adipocytes.Unacylated ghrelin restores insulin and autophagic signaling in skeletal muscle of diabetic mice.Tuning in to the rhythm of clock genes in skeletal muscle Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney.Faecalibacterium prausnitzii treatment improves hepatic health and reduces adipose tissue inflammation in high-fat fed mice.Gestational Protein Restriction Impairs Glucose Disposal in the Gastrocnemius Muscles of Female Rats.Natriuretic peptides promote glucose uptake in a cGMP-dependent manner in human adipocytes.A Tbc1d1 Ser231Ala-knockin mutation partially impairs AICAR- but not exercise-induced muscle glucose uptake in mice.Enhanced insulin signaling in human skeletal muscle and adipose tissue following gastric bypass surgery.The cell biology of systemic insulin function.Biologically anchored knowledge expansion approach uncovers KLF4 as a novel insulin signaling regulator

P2860

Q24324368-AD7CF463-1843-4C3D-B05C-8A5D8F4B1292 Q27339452-37E3F554-1E2E-4E60-8DBA-86C58AB23FFA Q30274807-4FA93452-A571-40E1-8498-6B0C3EE3B9DA Q30277981-9B980A74-D687-4CED-AF5F-49B97CC37592 Q30278610-FBF24088-83A9-436C-9311-B8341DB60D1C Q30279290-04B48A45-9C75-42DE-9C77-DF0665D1D633 Q30301274-DEE64515-7BB1-408E-8C00-24D57A8CBC18 Q30352469-C455D31B-8B8A-4057-888B-7CDF6300FA8A Q30411622-23EF0C2F-3E7B-4553-8422-46E54A721C96 Q33855536-5B573BA0-F6DD-4E47-AFDA-08BAAF8F55EF Q33901226-5C233B03-88F0-4B91-864B-8AF0E7FF4177 Q34258911-7C0AD78D-7183-469D-9467-EE33F194B7BC Q34644274-42A264F7-FAE3-41E0-9602-1CF5624B5EC5 Q35662057-14EE2489-1E28-4C1B-94D8-6E1A7C7B1049 Q35998271-0A8A83EB-8C21-4BEA-A818-F4BE72040A37 Q36274510-D61645A4-8A2D-4CAE-8D0C-3036AD3B8E51 Q36936312-E529A993-8EE1-4947-8BEC-6B8774870E78 Q37012363-9D4E03FE-66FD-4B5D-ABEC-87FB439EFA57 Q37092789-AFDE4B79-179C-4863-898D-3AE3557FBCCB Q38151511-AA18B133-C83B-4230-A99C-F4B170E800EC Q38359174-1216A9EF-646B-4CC2-9266-510E348DE3B0 Q38428510-420F386A-61A0-450D-A677-5B948401D4DD Q38742105-B31CF630-0964-48CD-BE84-44FDAAB3CD5C Q38816596-0AFBC2BA-93BF-4F5E-9CE1-C41298F7FAE5 Q39155096-D7BC0419-0D9A-42A8-B8D5-319CA719638A Q40675125-59FD5519-FE34-4149-900D-0FE94373B2BB Q41967486-D2B11E01-C2C9-4D5F-8794-5AABEC59DBDC Q42481916-D810F35D-9823-411E-AA16-AE8C483C82D2 Q46390377-748D7326-E9C5-4ECF-B244-2CDFA653A1AC Q47821534-86D233F3-0F00-4B46-A3C2-09DC5B561E14 Q48215808-0AE0FB16-E656-424F-9941-6ACCEF57F3BB Q50478355-EE5D2A98-FEFF-4028-B033-013B4D6EE447 Q51301598-D3FE12C1-3FD1-49D0-A959-216FF072F910 Q52603907-56075D16-B7E0-4D12-80FE-ADBDC99CEBB2 Q58707437-B13F6F7B-36A5-400D-81ED-04A520FD42A1

P2860

Deletion of Rab GAP AS160 modifies glucose uptake and GLUT4 translocation in primary skeletal muscles and adipocytes and impairs glucose homeostasis.

http://www.wikidata.org/entity/Q30416318

description

2012 nî lūn-bûn

@nan

2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

name

Deletion of Rab GAP AS160 modi ...... d impairs glucose homeostasis.

@ast

Deletion of Rab GAP AS160 modi ...... d impairs glucose homeostasis.

@en

type

label

Deletion of Rab GAP AS160 modi ...... d impairs glucose homeostasis.

@ast

Deletion of Rab GAP AS160 modi ...... d impairs glucose homeostasis.

@en

prefLabel

Deletion of Rab GAP AS160 modi ...... d impairs glucose homeostasis.

@ast

Deletion of Rab GAP AS160 modi ...... d impairs glucose homeostasis.

@en

P1433

Q30416318-87D2DAB3-C771-41C5-A3ED-C29A61AF3968

P1476

Q30416318-E73B12ED-BA13-4907-9006-C9599B511BD9

P2093

Q30416318-00CDEAC2-E873-4932-9F7F-6FBE22BD92FF

Q30416318-76D6E0CF-6901-49E3-BBEE-CE397352058B

Q30416318-7C61AF8D-2231-42F9-BA58-32B33654D613

Q30416318-84DA4A6B-00A5-40FD-9523-02B728E3EE5F

Q30416318-AF3FB476-62BA-4E43-9E39-B5EEEF2E0071

P2860

Q30416318-060CCEDB-FD7F-4A05-BDFC-575159844357

Q30416318-09481447-6C0A-4C58-995B-173079E05BF5

Q30416318-0F4C6DDD-E97D-4F9C-8D09-A3DCC0EF4F84

Q30416318-13C765E8-9BB8-452E-8CDF-EA8E846AFF62

Q30416318-1615A463-7BED-48AD-87DE-C85681358BC3

Q30416318-195BF6AE-A464-4515-9522-A90AF1C8AEAA

Q30416318-1F15DC12-49A0-4BF1-82BF-421AC27009FF

Q30416318-23BE2347-49F2-4560-87B1-18739016BDA0

Q30416318-262E7D84-389E-49A8-B84F-67057F21ECD3

Q30416318-26D2D0C5-67A5-4793-833E-C349AA5C6272

P304

Q30416318-9B859B9E-76EC-4E8F-99B1-A852939072FC

P31

Q30416318-3F914BEC-7D62-4C65-B501-E96D490F64F1

P356

Q30416318-1C6F0B13-B061-481F-895C-E61C0216379C

P433

Q30416318-04783467-8D34-467A-B994-99A4D3907700

P478

Q30416318-54454DCC-10E4-4693-9EE9-4D4E9DF059CD

P577

Q30416318-70885B12-BD52-4062-A0AB-16A67F97A402

P5875

Q30416318-0C1067B0-F9A7-434F-BB3C-A7E61CCD6DF8

P698

Q30416318-6568358A-A534-420B-8818-853358DB32A3

P921

Q30416318-591D6233-74AF-4AE7-9677-F540FA6DDF24

Q30416318-7f482a33-8e63-48d1-b969-f4ae4e2b6e26

P932

Q30416318-37305D60-D56C-4D62-A453-1DEBD546CE98

P356

AJPENDO.00316.2012

P1433

American Journal of Physiology - Endocrinology and Metabolism

P1476

Deletion of Rab GAP AS160 modi ...... d impairs glucose homeostasis.

@en

P2093

Joseph R Stevens

http://www.w3.org/2001/XMLSchema#string

Melissa N Lansey

http://www.w3.org/2001/XMLSchema#string

Natalie N Walker

http://www.w3.org/2001/XMLSchema#string

Stefan R Hargett

http://www.w3.org/2001/XMLSchema#string

Susanna R Keller

http://www.w3.org/2001/XMLSchema#string

P2860

A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain

C2 domain-containing phosphoprotein CDP138 regulates GLUT4 insertion into the plasma membrane.

Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat

Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1

Muscle cells engage Rab8A and myosin Vb in insulin-dependent GLUT4 translocation

Cell surface labeling of glucose transporter isoform GLUT4 by bis-mannose photolabel. Correlation with stimulation of glucose transport in rat adipose cells by insulin and phorbol ester

AS160 phosphotyrosine-binding domain constructs inhibit insulin-stimulated GLUT4 vesicle fusion with the plasma membrane

Mice deficient in the insulin-regulated membrane aminopeptidase show substantial decreases in glucose transporter GLUT4 levels but maintain normal glucose homeostasis

Insulin-stimulated phosphorylation of the Rab GTPase-activating protein TBC1D1 regulates GLUT4 translocation

Prenatal androgen exposure programs metabolic dysfunction in female mice.

P304

E1273-86

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1152/AJPENDO.00316.2012

http://www.w3.org/2001/XMLSchema#string

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

303

http://www.w3.org/2001/XMLSchema#string

P577

2012-09-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

231210763

http://www.w3.org/2001/XMLSchema#string

P698

23011063

http://www.w3.org/2001/XMLSchema#string

P921

P932

3517634

http://www.w3.org/2001/XMLSchema#string