Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms. - Wikidata - wikimedia - TriplyDB

Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms.

Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms.

http://www.wikidata.org/entity/Q30416550

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Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer From human genome to cancer genome: the first decade Chromothripsis from DNA damage in micronuclei.Population-based structural variation discovery with Hydra-Multi.Mosaic copy number variation in human neurons Exploration of the gene fusion landscape of glioblastoma using transcriptome sequencing and copy number data A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy.Identification of structural variation in mouse genomes.New Insights in the Cytogenetic Practice: Karyotypic Chaos, Non-Clonal Chromosomal Alterations and Chromosomal Instability in Human Cancer and Therapy Response The elusive evidence for chromothripsis Towards accurate characterization of clonal heterogeneity based on structural variation Expanding the computational toolbox for mining cancer genomes.Neuroblastoma after childhood: prognostic relevance of segmental chromosome aberrations, ATRX protein status, and immune cell infiltration Spatial and temporal diversity in genomic instability processes defines lung cancer evolution.Open adjacencies and k-breaks: detecting simultaneous rearrangements in cancer genomes.Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a glioma Functional chromatin features are associated with structural mutations in cancer Characterization of structural variants with single molecule and hybrid sequencing approaches.Discovery of recurrent structural variants in nasopharyngeal carcinoma.Ploidy-Seq: inferring mutational chronology by sequencing polyploid tumor subpopulations Chromosome-breakage genomic instability and chromothripsis in breast cancer Inferring the global structure of chromosomes from structural variations.Integrated sequence and expression analysis of ovarian cancer structural variants underscores the importance of gene fusion regulation DNA copy number analysis of Grade II-III and Grade IV gliomas reveals differences in molecular ontogeny including chromothripsis associated with IDH mutation status.Lack of ROS1 Gene Rearrangement in Glioblastoma Multiforme Modeling the integration of bacterial rRNA fragments into the human cancer genome Whole genome sequence analysis links chromothripsis to EGFR, MDM2, MDM4, and CDK4 amplification in glioblastoma.Complex Breakpoints and Template Switching Associated with Non-canonical Termination of Homologous Recombination in Mammalian Cells.Behavior of replication origins in Eukaryota - spatio-temporal dynamics of licensing and firing Discovery and characterization of Alu repeat sequences via precise local read assembly.Translesion Polymerases Drive Microhomology-Mediated Break-Induced Replication Leading to Complex Chromosomal Rearrangements.Identification of significantly mutated regions across cancer types highlights a rich landscape of functional molecular alterations Whole-Genome Sequencing Reveals Diverse Models of Structural Variations in Esophageal Squamous Cell Carcinoma Local sequence assembly reveals a high-resolution profile of somatic structural variations in 97 cancer genomes.Complex Chromosomal Rearrangements in B-Cell Lymphoma: Evidence of Chromoanagenesis? A Case Report.The tandem duplicator phenotype as a distinct genomic configuration in cancer Role of the double-strand break repair pathway in the maintenance of genomic stability.When Genome Maintenance Goes Badly Awry.Enhancement of microhomology-mediated genomic rearrangements by transient loss of mouse Bloom syndrome helicase CTLPScanner: a web server for chromothripsis-like pattern detection

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P2860

Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms.

http://www.wikidata.org/entity/Q30416550

description

2013 nî lūn-bûn

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2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի փետրվարին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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Breakpoint profiling of 64 can ...... mology-independent mechanisms.

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Breakpoint profiling of 64 can ...... mology-independent mechanisms.

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Breakpoint profiling of 64 can ...... mology-independent mechanisms.

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Breakpoint profiling of 64 can ...... mology-independent mechanisms.

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Breakpoint profiling of 64 can ...... mology-independent mechanisms.

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Breakpoint profiling of 64 can ...... mology-independent mechanisms.

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Genome Research

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Breakpoint profiling of 64 can ...... mology-independent mechanisms.

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P2093

Gregory G Faust

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Ira M Hall

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Michael Lindberg

http://www.w3.org/2001/XMLSchema#string

Mitchell L Leibowitz

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Royden A Clark

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Ryan M Layer

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P2860

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer

Mechanisms of change in gene copy number

Data mining using the Catalogue of Somatic Mutations in Cancer BioMart

Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes

Mapping copy number variation by population-scale genome sequencing

The genomic complexity of primary human prostate cancer

Efficient de novo assembly of large genomes using compressed data structures

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

Complex landscapes of somatic rearrangement in human breast cancer genomes.

A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome

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5

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23

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Aaron R Quinlan

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235628145

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23410887

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3638133

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