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Chromosome-breakage genomic instability and chromothripsis in breast cancer

Chromosome-breakage genomic instability and chromothripsis in breast cancer

http://www.wikidata.org/entity/Q35204806

about

New Insights in the Cytogenetic Practice: Karyotypic Chaos, Non-Clonal Chromosomal Alterations and Chromosomal Instability in Human Cancer and Therapy Response Genomic amplification of 9p24.1 targeting JAK2, PD-L1, and PD-L2 is enriched in high-risk triple negative breast cancer.Remarkable similarities of chromosomal rearrangements between primary human breast cancers and matched distant metastases as revealed by whole-genome sequencing Chromothripsis and progression-free survival in metastatic colorectal cancer.Genome-wide copy number aberrations and HER2 and FGFR1 alterations in primary breast cancer by molecular inversion probe microarray.Chromothripsis in cancer cells: An update.Personalised pathway analysis reveals association between DNA repair pathway dysregulation and chromosomal instability in sporadic breast cancer.Genomic profiling of malignant phyllodes tumors reveals aberrations in FGFR1 and PI-3 kinase/RAS signaling pathways and provides insights into intratumoral heterogeneity.Chromothripsis in acute myeloid leukemia: Biological features and impact on survival.Genomic studies of multiple myeloma reveal an association between X chromosome alterations and genomic profile complexity.Chromothripsis in acute myeloid leukemia: biological features and impact on survival.Characterization of Camptothecin-induced Genomic Changes in the Camptothecin-resistant T-ALL-derived Cell Line CPT-K5.

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Chromosome-breakage genomic instability and chromothripsis in breast cancer

http://www.wikidata.org/entity/Q35204806

description

2014 nî lūn-bûn

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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2014 թվականի հուլիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Chromosome-breakage genomic instability and chromothripsis in breast cancer

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Chromosome-breakage genomic instability and chromothripsis in breast cancer

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type

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Chromosome-breakage genomic instability and chromothripsis in breast cancer

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Chromosome-breakage genomic instability and chromothripsis in breast cancer

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Chromosome-breakage genomic instability and chromothripsis in breast cancer

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Chromosome-breakage genomic instability and chromothripsis in breast cancer

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Chromosome-breakage genomic instability and chromothripsis in breast cancer

@en

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Elizabeth Lenkiewicz

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Ewa Przybytkowski

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Kathleen Klein

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Mark Basik

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Michael T Barrett

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Sheida Nabavi

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Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer

Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

Criteria for inference of chromothripsis in cancer genomes

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Complex chromosomal rearrangements mediated by break-induced replication involve structure-selective endonucleases.

Molecular portraits of human breast tumours

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms.

The use of ultra-dense array CGH analysis for the discovery of micro-copy number alterations and gene fusions in the cancer genome

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1471-2164-15-579

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10.1186/1471-2164-15-579

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15

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Celia Greenwood

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