Allosteric modulation of GABA(A) receptor subtypes:effects on visual recognition and visuospatial working memory in rhesus monkeys [corrected]. - Wikidata - wikimedia - TriplyDB

Allosteric modulation of GABA(A) receptor subtypes:effects on visual recognition and visuospatial working memory in rhesus monkeys [corrected].

Allosteric modulation of GABA(A) receptor subtypes:effects on visual recognition and visuospatial working memory in rhesus monkeys [corrected].

http://www.wikidata.org/entity/Q30429949

about

Preclinical animal anxiety research - flaws and prejudices.Ionotropic GABA receptor antagonism-induced adverse outcome pathways for potential neurotoxicity biomarkers Negative modulation of α₅ GABAA receptors in rats may partially prevent memory impairment induced by MK-801, but not amphetamine- or MK-801-elicited hyperlocomotion Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABAA receptors containing the α5 subunit.Emergence delirium with transient associative agnosia and expressive aphasia reversed by flumazenil in a pediatric patient.The hypocretin/orexin antagonist almorexant promotes sleep without impairment of performance in rats Disinhibition, an emerging pharmacology of learning and memory Amnestic drugs in the odor span task: Effects of flunitrazepam, zolpidem and scopolamine.Behavioral pharmacology of the odor span task: Effects of flunitrazepam, ketamine, methamphetamine and methylphenidate.GABAergic inhibitory neurons as therapeutic targets for cognitive impairment in schizophrenia.

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P2860

Allosteric modulation of GABA(A) receptor subtypes:effects on visual recognition and visuospatial working memory in rhesus monkeys [corrected].

http://www.wikidata.org/entity/Q30429949

description

2013 nî lūn-bûn

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2013 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2013年の論文

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James M Cook

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Michael R Weed

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Nancy A Ator

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Paul L Soto

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Poonam Biawat

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Sundari K Rallapalli

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Terry Clayton

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P2860

PWZ-029, a compound with moderate inverse agonist functional selectivity at GABA(A) receptors containing alpha5 subunits, improves passive, but not active, avoidance learning in rats

Trace fear conditioning involves hippocampal alpha5 GABA(A) receptors

Reducing abuse liability of GABAA/benzodiazepine ligands via selective partial agonist efficacy at alpha1 and alpha2/3 subtypes.

Comparison of executive and visuospatial memory function in Huntington's disease and dementia of Alzheimer type matched for degree of dementia.

Novel positive allosteric modulators of GABAA receptors: do subtle differences in activity at alpha1 plus alpha5 versus alpha2 plus alpha3 subunits account for dissimilarities in behavioral effects in rats?

Effect of alpha subunit on allosteric modulation of ion channel function in stably expressed human recombinant gamma-aminobutyric acid(A) receptors determined using (36)Cl ion flux.

A comparative study of visuospatial memory and learning in Alzheimer-type dementia and Parkinson's disease.

Identification of a novel, selective GABA(A) alpha5 receptor inverse agonist which enhances cognition.

Anxiolytic-like effects of 8-acetylene imidazobenzodiazepines in a rhesus monkey conflict procedure.

An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA alpha5 receptors with cognition enhancing properties.

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