Distinguishing the roles of Topoisomerases I and II in relief of transcription-induced torsional stress in yeast rRNA genes.
about
Basic mechanisms in RNA polymerase I transcription of the ribosomal RNA genesRNase H2 roles in genome integrity revealed by unlinking its activitiesThe Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae.Divergent contributions of conserved active site residues to transcription by eukaryotic RNA polymerases I and IIMitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage.Torque measurement at the single-molecule levelTopoisomerase 1 and single-strand break repair modulate transcription-induced CAG repeat contraction in human cells.Mapping topoisomerase sites in mitochondrial DNA with a poisonous mitochondrial topoisomerase I (Top1mt).Targeted tandem duplication of a large chromosomal segment in Aspergillus oryzae.Transparent mediation-based access to multiple yeast data sources using an ontology driven interface.Genome-wide distribution of RNA-DNA hybrids identifies RNase H targets in tRNA genes, retrotransposons and mitochondriaThe chromosomal association of the Smc5/6 complex depends on cohesion and predicts the level of sister chromatid entanglement.Role for RNA:DNA hybrids in origin-independent replication priming in a eukaryotic system.RNA polymerase I activity is regulated at multiple steps in the transcription cycle: recent insights into factors that influence transcription elongation.Regulation of ribosomal RNA production by RNA polymerase I: does elongation come first?The importance of being supercoiled: how DNA mechanics regulate dynamic processesTranscription as a source of genome instability.Topoisomerase IIβ deficiency enhances camptothecin-induced apoptosis.Transcription-dependent dynamic supercoiling is a short-range genomic force.The Balancing Act of Ribonucleotides in DNAR-loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation.Structure-function analysis of Hmo1 unveils an ancestral organization of HMG-Box factors involved in ribosomal DNA transcription from yeast to human.Reversible Top1 cleavage complexes are stabilized strand-specifically at the ribosomal replication fork barrier and contribute to ribosomal DNA stabilityThe torsional state of DNA within the chromosome.Supercoiling in DNA and chromatin.The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability.Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast.Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instabilityGenome-wide ChIP-seq analysis of human TOP2B occupancy in MCF7 breast cancer epithelial cells.A targeting modality for destruction of RNA polymerase I that possesses anticancer activity.Antisense transcripts enhanced by camptothecin at divergent CpG-island promoters associated with bursts of topoisomerase I-DNA cleavage complex and R-loop formation.The Top1 paradox: Friend and foe of the eukaryotic genome.Topoisomerase IIα promotes activation of RNA polymerase I transcription by facilitating pre-initiation complex formation.Topological constraints impair RNA polymerase II transcription and causes instability of plasmid-borne convergent genesTranscriptional inhibition by DNA torsional stress.Chromatin regulates DNA torsional energy via topoisomerase II-mediated relaxation of positive supercoils.Chromatin determinants impart camptothecin sensitivity.Topoisomerase II is required for the production of long Pol II gene transcripts in yeast.Physiological Roles of DNA Double-Strand Breaks.Immunoprecipitation of RNA:DNA Hybrids from Budding Yeast.
P2860
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P2860
Distinguishing the roles of Topoisomerases I and II in relief of transcription-induced torsional stress in yeast rRNA genes.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Distinguishing the roles of To ...... al stress in yeast rRNA genes.
@ast
Distinguishing the roles of To ...... al stress in yeast rRNA genes.
@en
type
label
Distinguishing the roles of To ...... al stress in yeast rRNA genes.
@ast
Distinguishing the roles of To ...... al stress in yeast rRNA genes.
@en
prefLabel
Distinguishing the roles of To ...... al stress in yeast rRNA genes.
@ast
Distinguishing the roles of To ...... al stress in yeast rRNA genes.
@en
P2093
P2860
P50
P356
P1476
Distinguishing the roles of To ...... al stress in yeast rRNA genes.
@en
P2093
Ann L Beyer
Jeffrey S Smith
Martha L Sikes
Mitchell M Smith
Robert D Hontz
Tashima E Lambert
Yvonne N Osheim
P2860
P304
P356
10.1128/MCB.00589-10
P407
P577
2010-11-22T00:00:00Z