Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels.
about
Psychiatric Disorders and TRP Channels: Focus on Psychotropic DrugsAcute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in MiceTransient receptor potential canonical 4 and 5 proteins as targets in cancer therapeuticsDeletion of Rapgef6, a candidate schizophrenia susceptibility gene, disrupts amygdala function in mice.Selectivity and evolutionary divergence of metabotropic glutamate receptors for endogenous ligands and G proteins coupled to phospholipase C or TRP channelsModulation of innate and learned sexual behaviors by the TRP channel Painless expressed in the fruit fly brain: behavioral genetic analysis and its implicationsCanonical transient receptor potential 4 and its small molecule modulators.Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channelsRegulator of G-protein signalling and GoLoco proteins suppress TRPC4 channel function via acting at Gαi/o.Dynamic NHERF interaction with TRPC4/5 proteins is required for channel gating by diacylglycerol.TRPC Channels: Prominent Candidates of Underlying Mechanism in Neuropsychiatric Diseases.Diminishing fear: Optogenetic approach toward understanding neural circuits of fear control.Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice.Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory.New Aspects of the Contribution of ER to SOCE Regulation: TRPC Proteins as a Link Between Plasma Membrane Ion Transport and Intracellular Ca2+ Stores.Distribution of type I corticotropin-releasing factor (CRF1) receptors on GABAergic neurons within the basolateral amygdala.Loss of Transient Receptor Potential Ankyrin 1 Channel Deregulates Emotion, Learning and Memory, Cognition, and Social Behavior in Mice.Muscarinic receptor-induced contractions of the detrusor are impaired in TRPC4 deficient mice.Remarkable Progress with Small-Molecule Modulation of TRPC1/4/5 Channels: Implications for Understanding the Channels in Health and Disease.Activation of TRPC1 Channel by Metabotropic Glutamate Receptor mGluR5 Modulates Synaptic Plasticity and Spatial Working Memory
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P2860
Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels.
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2014 nî lūn-bûn
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2014 թուականի Մարտին հրատարակուած գիտական յօդուած
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2014 թվականի մարտին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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name
Decreased anxiety-like behavio ...... f mice lacking TRPC4 channels.
@ast
Decreased anxiety-like behavio ...... f mice lacking TRPC4 channels.
@en
type
label
Decreased anxiety-like behavio ...... f mice lacking TRPC4 channels.
@ast
Decreased anxiety-like behavio ...... f mice lacking TRPC4 channels.
@en
prefLabel
Decreased anxiety-like behavio ...... f mice lacking TRPC4 channels.
@ast
Decreased anxiety-like behavio ...... f mice lacking TRPC4 channels.
@en
P2093
P2860
P50
P1476
Decreased anxiety-like behavio ...... of mice lacking TRPC4 channels
@en
P2093
Antonio Riccio
Gui Lan Yao
Kiersten S Smith
Svetlana Gapon
Uwe Rudolph
Vadim Y Bolshakov
P2860
P304
P356
10.1523/JNEUROSCI.2274-13.2014
P407
P577
2014-03-01T00:00:00Z