Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.
about
Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice.Nonlinear relationship between spike-dependent calcium influx and TRPC channel activation enables robust persistent spiking in neurons of the anterior cingulate cortex.Na+ entry through heteromeric TRPC4/C1 channels mediates (-)Englerin A-induced cytotoxicity in synovial sarcoma cells.TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation.Pico145 - powerful new tool for TRPC1/4/5 channels.Remarkable Progress with Small-Molecule Modulation of TRPC1/4/5 Channels: Implications for Understanding the Channels in Health and Disease.Importance of a 4-Alkyl Substituent for Activity in the Englerin Series.Activation of TRPC1 Channel by Metabotropic Glutamate Receptor mGluR5 Modulates Synaptic Plasticity and Spatial Working MemoryDual action of the Gα-PLCβ-PI(4,5)P pathway on TRPC1/4 and TRPC1/5 heterotetramers
P2860
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P2860
Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
Picomolar, selective, and subt ...... ibition of TRPC1/4/5 channels.
@en
Picomolar, selective, and subt ...... ibition of TRPC1/4/5 channels.
@en-gb
type
label
Picomolar, selective, and subt ...... ibition of TRPC1/4/5 channels.
@en
Picomolar, selective, and subt ...... ibition of TRPC1/4/5 channels.
@en-gb
prefLabel
Picomolar, selective, and subt ...... ibition of TRPC1/4/5 channels.
@en
Picomolar, selective, and subt ...... ibition of TRPC1/4/5 channels.
@en-gb
P2093
P2860
P50
P356
P1154
2-s2.0-85019603269
P1476
Picomolar, selective, and subt ...... ibition of TRPC1/4/5 channels.
@en
P2093
Hannah J Gaunt
Hollie L Appleby
Hussein N Rubaiy
Katarina Miteva
Katie E Musialowski
Katsuhiko Muraki
Marc A Bailey
Matthias Henrot
Melanie J Ludlow
Nicola M Blythe
P2860
P304
P356
10.1074/JBC.M116.773556
P407
P5530
P577
2017-03-21T00:00:00Z
P6179
1084153190