Direct binding of hepatitis C virus core to gC1qR on CD4+ and CD8+ T cells leads to impaired activation of Lck and Akt. - Wikidata - wikimedia - TriplyDB

Direct binding of hepatitis C virus core to gC1qR on CD4+ and CD8+ T cells leads to impaired activation of Lck and Akt.

Direct binding of hepatitis C virus core to gC1qR on CD4+ and CD8+ T cells leads to impaired activation of Lck and Akt.

http://www.wikidata.org/entity/Q30433630

about

Induction of p38- and gC1qR-dependent IL-8 expression in pulmonary fibroblasts by soluble hepatitis C core protein.Direct effects of hepatitis C virus on the lymphoid cells SOCS1 and SOCS3 are targeted by hepatitis C virus core/gC1qR ligation to inhibit T-cell function Effect of hepatitis C virus core protein on the molecular profiling of human B lymphocytes Differential regulation of SOCS-1 signalling in B and T lymphocytes by hepatitis C virus core protein Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence Contribution of Genome-Wide HCV Genetic Differences to Outcome of Interferon-Based Therapy in Caucasian American and African American Patients Myeloid-derived suppressor cells: the dark knight or the joker in viral infections?Extracellular HCV-core protein induces an immature regulatory phenotype in NK cells: implications for outcome of acute infection Tim-3 negatively regulates IL-12 expression by monocytes in HCV infection.Frequency of gC1qR+CD4+ T cells increases during acute hepatitis C virus infection and remains elevated in patients with chronic infection.HCV+ hepatocytes induce human regulatory CD4+ T cells through the production of TGF-beta Plasmodium falciparum uses gC1qR/HABP1/p32 as a receptor to bind to vascular endothelium and for platelet-mediated clumping.Hepatitis C virus core protein inhibits interferon production by a human plasmacytoid dendritic cell line and dysregulates interferon regulatory factor-7 and signal transducer and activator of transcription (STAT) 1 protein expression.Expression of hepatitis C virus core protein in hepatocytes does not modulate proliferation or apoptosis of CD8+ T cells.Virus-related liver cirrhosis: molecular basis and therapeutic options.The wild-type hepatitis C virus core inhibits initiation of antigen-specific T- and B-cell immune responses in BALB/c mice A gC1qR prevents white spot syndrome virus replication in the freshwater crayfish Pacifastacus leniusculus Intracellular innate immune cascades and interferon defenses that control hepatitis C virus Programmed death-1 affects suppressor of cytokine signaling-1 expression in T cells during hepatitis C infection.Immunogenicity of Multi-Epitope DNA and Peptide Vaccine Candidates Based on Core, E2, NS3 and NS5B HCV Epitopes in BALB/c Mice.Hepatitis C virus core protein inhibits tumor necrosis factor alpha-mediated apoptosis by a protective effect involving cellular FLICE inhibitory protein.The human fetal immune response to hepatitis C virus exposure in utero.Role of the exogenous HCV core protein in the interaction of human hepatocyte proliferation and macrophage sub-populations Viral modulation of T-cell receptor signaling Identification of the gC1qR sites for the HIV-1 viral envelope protein gp41 and the HCV core protein: Implications in viral-specific pathogenesis and therapy.Hepatitis C virus-mediated modulation of cellular immunity.Role of different regions of the hepatitis C virus genome in the therapeutic response to interferon-based treatment.Hepatitis C virus core protein stimulates fibrogenesis in hepatic stellate cells involving the obese receptor.Insights into Myeloid-Derived Suppressor Cells in Inflammatory Diseases.T-bet-mediated Tim-3 expression dampens monocyte function during chronic hepatitis C virus infection.Preferential association of hepatitis C virus with CD19+ B cells is mediated by complement system.C1q as an autocrine and paracrine regulator of cellular functions.Immune modulation by the hepatitis C virus core protein.HCV-specific T-cell responses in injecting drug users: evidence for previous exposure to HCV and a role for CD4+ T cells focussing on nonstructural proteins in viral clearance.Hepatitis C virus-induced myeloid-derived suppressor cells regulate T-cell differentiation and function via the signal transducer and activator of transcription 3 pathway.KLRG1 impairs CD4+ T cell responses via p16ink4a and p27kip1 pathways: role in hepatitis B vaccine failure in individuals with hepatitis C virus infection.Tim-3 pathway controls regulatory and effector T cell balance during hepatitis C virus infection.Effect of the infectious dose and the presence of hepatitis C virus core gene on mouse intrahepatic CD8 T cells.PD-1 modulates regulatory T cells and suppresses T-cell responses in HCV-associated lymphoma.

P2860

Q24814742-88458E19-7C07-4670-B129-1618BA6FD48D Q26992142-0C22F4D7-9676-4320-8601-C4237CAB3DC0 Q27472767-C0F3325D-5CAB-41B8-AA79-C3517EC1E13A Q27473390-BF6BAA9E-557B-42A6-8715-395F7B7359C1 Q27487006-53D7F5E5-C0D7-4FA4-93C7-2EDFC4405D4D Q27488844-D0E0366F-3F71-45B2-A235-587E01848A09 Q27490885-221BE5D1-600C-468E-8815-94A72DAD22B9 Q30411008-1B123BEC-789E-4447-8B8F-211388D26290 Q30411437-2C3B144A-F77F-4A26-90CB-22284108078A Q30432023-866D3C1C-4CA4-4FA8-9BB7-2EDE4BF6B246 Q30434900-B6A8C066-28AE-46D7-9E12-4B4FB8ED32D7 Q30435033-B3D5EC05-0DB7-4B10-983B-2CBB4DAD8493 Q33301011-BC120B90-6092-44D1-92F4-220C9B7E6A36 Q33553433-951AE9C4-E51F-41A6-8217-298CAFF74590 Q33607229-86CFDBB9-D30B-4F30-A2FE-36BDC3A2CFFF Q33718267-E3E52E1E-5E32-4DC7-8663-31251962B02D Q33962697-75ABE038-5680-47C4-A501-D9EEEE707A86 Q34178374-5CE47694-7458-473F-AC2F-80CC44BA5FA5 Q34208090-D3FD55B7-0A8D-4C48-88BE-5088CB58EBC3 Q34259893-918BCD84-BE83-47FB-BC0B-3C781D70ADAD Q34546149-D967F93E-A735-48CB-8909-88E72F64CC6C Q34647482-A48905A4-0EE0-47C5-A001-93D51FF987CB Q34763599-8677CC1F-9AB5-408D-8B8B-A710094E39A6 Q35284854-018F5CCF-E36C-492B-BB6C-6453A8601978 Q36540182-0380A3CC-DC62-450C-8AAF-C5C7D98DF126 Q37180378-18620A2D-0565-499E-850F-B8F4E810F435 Q38036576-9C5B7D71-2F42-4C57-B243-C5F0C57A64A5 Q38121422-BDF47964-FE0B-4E85-996B-213E61C48D6B Q38321928-6F2BBFCF-F08E-4493-9C82-26B2C0C6CC3D Q38492085-2E173A07-9AD5-400F-AE7E-682EDB65D622 Q38733708-9FB1052C-307B-471B-ADBC-3AC1062F8483 Q38738490-5A452EEC-DAD9-48B6-9427-64FEB0EE7291 Q39028351-E7E15B02-0419-486A-A3A7-3ABB58537B9F Q39090584-3C8E9F75-4B9F-4539-812A-CAB8531EE9E1 Q39415291-54B5E9BF-00C2-4321-9176-E2117FE1A8C7 Q40686250-42931172-6173-46C5-804F-AF9F21244BF7 Q41877181-A76D89D6-C699-4002-991D-1DADD7879D06 Q42071282-ED40113A-F201-47BC-9855-7A1E989E3528 Q42240917-53D7CA22-31E9-432C-87A3-AFD8BE9BC1DF Q42585404-5C07C322-1FF8-40CF-B97E-0DC7C2CFBDC4

P2860

Direct binding of hepatitis C virus core to gC1qR on CD4+ and CD8+ T cells leads to impaired activation of Lck and Akt.

http://www.wikidata.org/entity/Q30433630

description

2004 nî lūn-bûn

@nan

2004 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Direct binding of hepatitis C ...... red activation of Lck and Akt.

@ast

Direct binding of hepatitis C ...... red activation of Lck and Akt.

@en

type

label

Direct binding of hepatitis C ...... red activation of Lck and Akt.

@ast

Direct binding of hepatitis C ...... red activation of Lck and Akt.

@en

prefLabel

Direct binding of hepatitis C ...... red activation of Lck and Akt.

@ast

Direct binding of hepatitis C ...... red activation of Lck and Akt.

@en

P1433

Q30433630-E1CE1EBD-BBE7-481F-A74D-340392F07AC4

P1476

Q30433630-20AE1F93-DB1B-466F-B603-6CDCF65731FC

P2093

Q30433630-03F2DAA8-4C43-46EC-ABF5-AD21632065D2

Q30433630-06ECC679-1E34-4BF9-94D6-36FFE9709275

Q30433630-6C080436-88AD-43CE-92A2-ACF2004B8917

Q30433630-B1FB1857-C1E0-45F1-B9C5-5285B24F0CC8

Q30433630-C387B6BB-249F-4C38-BC42-350B142EA717

P2860

Q30433630-007CE160-9E21-45E0-BCEA-8DDFFE2DBB76

Q30433630-107D614A-461E-4585-A429-A96310498193

Q30433630-127B8A31-007C-41C0-9CC7-D2E68DDC38AA

Q30433630-16CBE346-F741-469A-A610-F8279E335AB5

Q30433630-19C46425-2723-4BED-B9F7-7ABCCA20839C

Q30433630-25B23CA6-3A70-48DB-B6DD-C7389A1919B7

Q30433630-29CF8918-C3DC-4CAC-B2C6-E1FD39F79634

Q30433630-301D0EA6-A5C1-4A6C-BB51-D897121AAD2F

Q30433630-3B28B0CA-F96D-4D40-9467-D6656496B3EA

Q30433630-3DD41795-9B86-4A9D-B3E0-9E3B172A9B05

P304

Q30433630-62AC9609-0B6D-4ACB-A8C3-E8895ADB5009

P31

Q30433630-9892C4B0-E12F-4F87-9DC1-070F59F32D5B

P356

Q30433630-29B9A0E0-D15E-4CF2-8D1D-C9E7597051B9

P433

Q30433630-FA91CB56-EEF9-4048-8B6E-435D72F28B20

P478

Q30433630-1DE9CA4E-3CAB-4C6D-9B9A-204049246732

P577

Q30433630-2BB8DD1B-1777-4D31-8FCC-B961E9E16FED

P5875

Q30433630-36B2BFA3-01BC-4913-AD16-1ED4AFEFD0AE

P698

Q30433630-D40D0BB4-9497-413D-9329-96D1D1FC0251

P932

Q30433630-73CD5471-5B2A-4800-8CB1-0FA1C1AF8925

P356

JVI.78.12.6409-6419.2004

P1433

Journal of Virology

P1476

Direct binding of hepatitis C ...... red activation of Lck and Akt.

@en

P2093

Audrey Eisen-Vandervelde

http://www.w3.org/2001/XMLSchema#string

Evan M Cale

http://www.w3.org/2001/XMLSchema#string

Stephen N Waggoner

http://www.w3.org/2001/XMLSchema#string

Young S Hahn

http://www.w3.org/2001/XMLSchema#string

Zhi Qiang Yao

http://www.w3.org/2001/XMLSchema#string

P2860

Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation.

Cooperation of C1q receptors and integrins in C1q-mediated endothelial cell adhesion and spreading

Isolation and characterization of the kininogen-binding protein p33 from endothelial cells. Identity with the gC1q receptor

gC1q-R/p32, a C1q-binding protein, is a receptor for the InlB invasion protein of Listeria monocytogenes

Cellular protein modulates effects of human immunodeficiency virus type 1 Rev

Nonenveloped Nucleocapsids of Hepatitis C Virus in the Serum of Infected Patients

Abnormal priming of CD4(+) T cells by dendritic cells expressing hepatitis C virus core and E1 proteins.

Hepatitis C Virus Structural Proteins Impair Dendritic Cell Maturation and Inhibit In Vivo Induction of Cellular Immune Responses

Analysis of successful immune responses in persons infected with hepatitis C virus

Determinants of viral clearance and persistence during acute hepatitis C virus infection

P304

6409-6419

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/JVI.78.12.6409-6419.2004

http://www.w3.org/2001/XMLSchema#string

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

78

http://www.w3.org/2001/XMLSchema#string

P577

2004-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8542213

http://www.w3.org/2001/XMLSchema#string

P698

15163734

http://www.w3.org/2001/XMLSchema#string

P932

416530

http://www.w3.org/2001/XMLSchema#string