PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation. - Wikidata - wikimedia - TriplyDB

PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation.

PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation.

http://www.wikidata.org/entity/Q30435847

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The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis.Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling Ptk7 and Mcc, Unfancied Components in Non-Canonical Wnt Signaling and Cancer The role of Ryk and Ror receptor tyrosine kinases in Wnt signal transduction Wnt and planar cell polarity signaling in cystic renal disease The PTK7-related transmembrane proteins off-track and off-track 2 are co-receptors for Drosophila Wnt2 required for male fertility Filopodial-Tension Model of Convergent-Extension of Tissues A PTK7/Ror2 Co-Receptor Complex Affects Xenopus Neural Crest Migration The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear.The Molecular Basis of Radial Intercalation during Tissue Spreading in Early Development Protein tyrosine kinase 7 is essential for tubular morphogenesis of the Wolffian duct Molecular model for force production and transmission during vertebrate gastrulation Integration of planar cell polarity and ECM signaling in elongation of the vertebrate body plan Distinct apical and basolateral mechanisms drive planar cell polarity-dependent convergent extension of the mouse neural plate.PTK7-Src signaling at epithelial cell contacts mediates spatial organization of actomyosin and planar cell polarity.Cell segregation, mixing, and tissue pattern in the spinal cord of the Xenopus laevis neurula.PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium.Mouse primitive streak forms in situ by initiation of epithelial to mesenchymal transition without migration of a cell population.WNT5A/JNK and FGF/MAPK pathways regulate the cellular events shaping the vertebrate limb bud.Protein-tyrosine pseudokinase 7 (PTK7) directs cancer cell motility and metastasis.Serial analysis of gene expression in the chicken otocyst.Role of the epithelial-mesenchymal transition and its effects on embryonic stem cells.PTK7 marks the first human developmental EMT in vitro.PTK7 protein is decreased in epithelial ovarian carcinomas with poor prognosis Potential relation of aberrant proteolysis of human protein tyrosine kinase 7 (PTK7) chuzhoi by membrane type 1 matrix metalloproteinase (MT1-MMP) to congenital defects.PTK7+ Mononuclear Cells Express VEGFR2 and Contribute to Vascular Stabilization by Upregulating Angiopoietin-1.An essential and highly conserved role for Zic3 in left-right patterning, gastrulation and convergent extension morphogenesis.Local mechanical forces promote polarized junctional assembly and axis elongation in Drosophila.Insights into ectodomain shedding and processing of protein-tyrosine pseudokinase 7 (PTK7)Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis.The planar cell polarity pathway in vertebrate development.Principles of planar polarity in animal development Planar cell polarity: coordinating morphogenetic cell behaviors with embryonic polarity Planar cell polarity signaling: coordination of cellular orientation across tissues.Genetics of breast cancer bone metastasis: a sequential multistep pattern.PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling.Myosin II is not required for Drosophila tracheal branch elongation and cell intercalation.Vertebrate Axial Patterning: From Egg to Asymmetry.Downstream signaling and genome-wide regulatory effects of PTK7 pseudokinase and its proteolytic fragments in cancer cells.Identification of emergent motion compartments in the amniote embryo.

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P2860

PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation.

http://www.wikidata.org/entity/Q30435847

description

2009 nî lūn-bûn

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2009 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2009 թվականի մայիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

PTK7 is essential for polarize ...... ion during mouse gastrulation.

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PTK7 is essential for polarize ...... ion during mouse gastrulation.

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type

label

PTK7 is essential for polarize ...... ion during mouse gastrulation.

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PTK7 is essential for polarize ...... ion during mouse gastrulation.

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prefLabel

PTK7 is essential for polarize ...... ion during mouse gastrulation.

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PTK7 is essential for polarize ...... ion during mouse gastrulation.

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PTK7 is essential for polarize ...... ion during mouse gastrulation.

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P2093

Ammasi Periasamy

http://www.w3.org/2001/XMLSchema#string

Carol Burdsal

http://www.w3.org/2001/XMLSchema#string

Margot Williams

http://www.w3.org/2001/XMLSchema#string

Mark Conaway

http://www.w3.org/2001/XMLSchema#string

Raymond Keller

http://www.w3.org/2001/XMLSchema#string

Wei Wei Yen

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Xiaowei Lu

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P2860

The planar polarity gene strabismus regulates convergent extension movements in Xenopus.

Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse

The forces that shape embryos: physical aspects of convergent extension by cell intercalation

Mutations in VANGL1 associated with neural-tube defects

Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development

Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation

PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates

Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure

Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

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2039-2048

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scholarly article

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10.1242/DEV.030601

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12

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136

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Ann E Sutherland

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2009-05-13T00:00:00Z

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19439496

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2685725

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