PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation.
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The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis.Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signallingPtk7 and Mcc, Unfancied Components in Non-Canonical Wnt Signaling and CancerThe role of Ryk and Ror receptor tyrosine kinases in Wnt signal transductionWnt and planar cell polarity signaling in cystic renal diseaseThe PTK7-related transmembrane proteins off-track and off-track 2 are co-receptors for Drosophila Wnt2 required for male fertilityFilopodial-Tension Model of Convergent-Extension of TissuesA PTK7/Ror2 Co-Receptor Complex Affects Xenopus Neural Crest MigrationThe novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear.The Molecular Basis of Radial Intercalation during Tissue Spreading in Early DevelopmentProtein tyrosine kinase 7 is essential for tubular morphogenesis of the Wolffian ductMolecular model for force production and transmission during vertebrate gastrulationIntegration of planar cell polarity and ECM signaling in elongation of the vertebrate body planDistinct apical and basolateral mechanisms drive planar cell polarity-dependent convergent extension of the mouse neural plate.PTK7-Src signaling at epithelial cell contacts mediates spatial organization of actomyosin and planar cell polarity.Cell segregation, mixing, and tissue pattern in the spinal cord of the Xenopus laevis neurula.PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium.Mouse primitive streak forms in situ by initiation of epithelial to mesenchymal transition without migration of a cell population.WNT5A/JNK and FGF/MAPK pathways regulate the cellular events shaping the vertebrate limb bud.Protein-tyrosine pseudokinase 7 (PTK7) directs cancer cell motility and metastasis.Serial analysis of gene expression in the chicken otocyst.Role of the epithelial-mesenchymal transition and its effects on embryonic stem cells.PTK7 marks the first human developmental EMT in vitro.PTK7 protein is decreased in epithelial ovarian carcinomas with poor prognosisPotential relation of aberrant proteolysis of human protein tyrosine kinase 7 (PTK7) chuzhoi by membrane type 1 matrix metalloproteinase (MT1-MMP) to congenital defects.PTK7+ Mononuclear Cells Express VEGFR2 and Contribute to Vascular Stabilization by Upregulating Angiopoietin-1.An essential and highly conserved role for Zic3 in left-right patterning, gastrulation and convergent extension morphogenesis.Local mechanical forces promote polarized junctional assembly and axis elongation in Drosophila.Insights into ectodomain shedding and processing of protein-tyrosine pseudokinase 7 (PTK7)Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis.The planar cell polarity pathway in vertebrate development.Principles of planar polarity in animal developmentPlanar cell polarity: coordinating morphogenetic cell behaviors with embryonic polarityPlanar cell polarity signaling: coordination of cellular orientation across tissues.Genetics of breast cancer bone metastasis: a sequential multistep pattern.PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling.Myosin II is not required for Drosophila tracheal branch elongation and cell intercalation.Vertebrate Axial Patterning: From Egg to Asymmetry.Downstream signaling and genome-wide regulatory effects of PTK7 pseudokinase and its proteolytic fragments in cancer cells.Identification of emergent motion compartments in the amniote embryo.
P2860
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P2860
PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
PTK7 is essential for polarize ...... ion during mouse gastrulation.
@ast
PTK7 is essential for polarize ...... ion during mouse gastrulation.
@en
type
label
PTK7 is essential for polarize ...... ion during mouse gastrulation.
@ast
PTK7 is essential for polarize ...... ion during mouse gastrulation.
@en
prefLabel
PTK7 is essential for polarize ...... ion during mouse gastrulation.
@ast
PTK7 is essential for polarize ...... ion during mouse gastrulation.
@en
P2093
P2860
P356
P1433
P1476
PTK7 is essential for polarize ...... ion during mouse gastrulation.
@en
P2093
Ammasi Periasamy
Carol Burdsal
Margot Williams
Mark Conaway
Raymond Keller
Wei Wei Yen
Xiaowei Lu
P2860
P304
P356
10.1242/DEV.030601
P407
P577
2009-05-13T00:00:00Z