The RhoA activator GEF-H1/Lfc is a transforming growth factor-beta target gene and effector that regulates alpha-smooth muscle actin expression and cell migration
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Inflammatory microenvironment contributes to epithelial-mesenchymal transition in gastric cancerActin cytoskeleton in myofibroblast differentiation: ultrastructure defining form and driving functionMolecular mechanisms of epithelial-mesenchymal transitionTGF-b2 induction regulates invasiveness of Theileria-transformed leukocytes and disease susceptibilityTGF-β-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-ASignaling pathways that control rho kinase activity maintain the embryonic epicardial progenitor state.The epidermal growth factor receptor mediates tumor necrosis factor-alpha-induced activation of the ERK/GEF-H1/RhoA pathway in tubular epithelium.Macroscopic stiffening of embryonic tissues via microtubules, RhoGEF and the assembly of contractile bundles of actomyosin.Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cellsCentral role of the exchange factor GEF-H1 in TNF-α-induced sequential activation of Rac, ADAM17/TACE, and RhoA in tubular epithelial cells.GEF-H1 functions in apical constriction and cell intercalations and is essential for vertebrate neural tube closure.TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion.RalB regulates contractility-driven cancer dissemination upon TGFβ stimulation via the RhoGEF GEF-H1A novel function for p21Cip1 and acetyltransferase p/CAF as critical transcriptional regulators of TGFβ-mediated breast cancer cell migration and invasion.Bves modulates tight junction associated signaling.Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription.Cells lacking β-actin are genetically reprogrammed and maintain conditional migratory capacity.Grhl3 and GEF19 in the front rho.Delayed stress fiber formation mediates pulmonary myofibroblast differentiation in response to TGF-β.Microtubules regulate GEF-H1 in response to extracellular matrix stiffness.miR-31 is a negative regulator of fibrogenesis and pulmonary fibrosis.Endogenous Semaphorin-7A Impedes Human Lung Fibroblast DifferentiationSignaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transition.Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton.The Dual Role of TGFβ in Human Cancer: From Tumor Suppression to Cancer MetastasisGEF-H1 is necessary for neutrophil shear stress-induced migration during inflammation.Signaling mechanisms that regulate smooth muscle cell differentiation.The complex regulation of TGF-β in cardiovascular disease.Cytoskeletal signaling in TGFβ-induced epithelial-mesenchymal transition.Epo inhibits the fibrosis and migration of Müller glial cells induced by TGF-β and high glucose.Real-time quantitative monitoring of hiPSC-based model of macular degeneration on Electric Cell-substrate Impedance Sensing microelectrodes.Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells.The guanine nucleotide exchange factor Vav3 regulates differentiation of progenitor cells in the developing mouse retina.Guanine nucleotide exchange factor H1 can be a new biomarker of melanoma.Biallelic Mutation of ARHGEF18, Involved in the Determination of Epithelial Apicobasal Polarity, Causes Adult-Onset Retinal Degeneration.An oncogenic KRAS transcription program activates the RHOGEF ARHGEF2 to mediate transformed phenotypes in pancreatic cancer.α2β1 integrin and RhoA mediates electric field-induced ligament fibroblast migration directionality.Transforming growth factor-β enhances Rho-kinase activity and contraction in airway smooth muscle via the nucleotide exchange factor ARHGEF1.Expression of fibulin-6 in failing hearts and its role for cardiac fibroblast migration.TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer.
P2860
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P2860
The RhoA activator GEF-H1/Lfc is a transforming growth factor-beta target gene and effector that regulates alpha-smooth muscle actin expression and cell migration
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The RhoA activator GEF-H1/Lfc ...... expression and cell migration
@ast
The RhoA activator GEF-H1/Lfc ...... expression and cell migration
@en
The RhoA activator GEF-H1/Lfc ...... expression and cell migration
@en-gb
type
label
The RhoA activator GEF-H1/Lfc ...... expression and cell migration
@ast
The RhoA activator GEF-H1/Lfc ...... expression and cell migration
@en
The RhoA activator GEF-H1/Lfc ...... expression and cell migration
@en-gb
prefLabel
The RhoA activator GEF-H1/Lfc ...... expression and cell migration
@ast
The RhoA activator GEF-H1/Lfc ...... expression and cell migration
@en
The RhoA activator GEF-H1/Lfc ...... expression and cell migration
@en-gb
P2860
P50
P356
P1476
The RhoA activator GEF-H1/Lfc ...... expression and cell migration
@en
P2093
Anna Tsapara
Phillip Luthert
P2860
P304
P356
10.1091/MBC.E09-07-0567
P577
2010-01-20T00:00:00Z