Focal adhesion kinase is required for the spatial organization of the leading edge in migrating cells.
about
Phosphorylated alpha-actinin and protein-tyrosine phosphatase 1B coregulate the disassembly of the focal adhesion kinase x Src complex and promote cell migrationThe SRC-associated protein CUB Domain-Containing Protein-1 regulates adhesion and motilityCoronin 1C negatively regulates cell-matrix adhesion and motility of intestinal epithelial cellsEstrogen-dependent sushi domain containing 3 regulates cytoskeleton organization and migration in breast cancer cellsFocal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motilityRACK1 targets the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway to link integrin engagement with focal adhesion disassembly and cell motilityThe FAK-Arp2/3 interaction promotes leading edge advance and haptosensing by coupling nascent adhesions to lamellipodia actin.LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase.PIP kinases define PI4,5P₂signaling specificity by association with effectorsStochastic model of integrin-mediated signaling and adhesion dynamics at the leading edges of migrating cells.CaM kinase II delta2-dependent regulation of vascular smooth muscle cell polarization and migrationVascular growth responses to chronic arterial occlusion are unaffected by myeloid specific focal adhesion kinase (FAK) deletion.FAK is required for tension-dependent organization of collective cell movements in Xenopus mesendodermInhibition of focal adhesion kinase by PF-562,271 inhibits the growth and metastasis of pancreatic cancer concomitant with altering the tumor microenvironment.Focal adhesion kinase modulates activation of NF-kappaB by flow in endothelial cells.Differential requirement for focal adhesion kinase signaling in cancer progression in the transgenic adenocarcinoma of mouse prostate modelPaxillin-kinase-linker tyrosine phosphorylation regulates directional cell migration.Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion.Focal adhesion kinase as a regulator of cell tension in the progression of cancer.Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinaseCellular responses to substrate topography: role of myosin II and focal adhesion kinase.Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation.c-Src-mediated epithelial cell migration and invasion regulated by PDZ binding site.Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation.FAK phosphorylation at Tyr-925 regulates cross-talk between focal adhesion turnover and cell protrusion.A novel protocol of whole mount electro-immunofluorescence stainingBroad phenotypic changes associated with gain of radiation resistance in head and neck squamous cell cancermTOR regulates the invasive properties of synovial fibroblasts in rheumatoid arthritis.Emerging role of paxillin-PKL in regulation of cell adhesion, polarity and migrationFocal adhesion kinase stabilizes the cytoskeleton.Mertk deficiency affects macrophage directional migration via disruption of cytoskeletal organization.Snail1 controls epithelial-mesenchymal lineage commitment in focal adhesion kinase-null embryonic cells.Dentin phosphoprotein (DPP) activates integrin-mediated anchorage-dependent signals in undifferentiated mesenchymal cells.RhoH is critical for cell-microenvironment interactions in chronic lymphocytic leukemia in mice and humans.Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamicsLiver X receptor regulates rheumatoid arthritis fibroblast-like synoviocyte invasiveness, matrix metalloproteinase 2 activation, interleukin-6 and CXCL10.PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motilityCAP1 (Cyclase-Associated Protein 1) Exerts Distinct Functions in the Proliferation and Metastatic Potential of Breast Cancer Cells Mediated by ERK.Formation of Kv2.1-FAK complex as a mechanism of FAK activation, cell polarization and enhanced motilityFAK is a critical regulator of neuroblastoma liver metastasis.
P2860
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P2860
Focal adhesion kinase is required for the spatial organization of the leading edge in migrating cells.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Focal adhesion kinase is requi ...... ading edge in migrating cells.
@ast
Focal adhesion kinase is requi ...... ading edge in migrating cells.
@en
type
label
Focal adhesion kinase is requi ...... ading edge in migrating cells.
@ast
Focal adhesion kinase is requi ...... ading edge in migrating cells.
@en
prefLabel
Focal adhesion kinase is requi ...... ading edge in migrating cells.
@ast
Focal adhesion kinase is requi ...... ading edge in migrating cells.
@en
P2093
P356
P1476
Focal adhesion kinase is requi ...... ading edge in migrating cells.
@en
P2093
E Daniel Hershey
Hilary E Beggs
J Thomas Parsons
Jill K Slack-Davis
Karen H Martin
Louis F Reichardt
Marcin Iwanicki
Natalia Sergina
Robert W Tilghman
P304
P356
10.1242/JCS.02380
P407
P577
2005-05-24T00:00:00Z