TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling
about
Mechanical stretch: physiological and pathological implications for human vascular endothelial cellsMechanosensitive mechanisms in transcriptional regulationEmerging role of TRP channels in cell migration: from tumor vascularization to metastasisklf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis.TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye.Mechanical stretch and PI3K signaling link cell migration and proliferation to coordinate epithelial tubule morphogenesis in the zebrafish pronephrosTRPV4 Regulates Breast Cancer Cell Extravasation, Stiffness and Actin CortexPhysiological mechanisms and therapeutic potential of bone mechanosensing.The interplay between cell signalling and mechanics in developmental processesProlonged mechanical stretch is associated with upregulation of hypoxia-inducible factors and reduced contraction in rat inferior vena cavaTRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasisMicrotubule dynamics regulate cyclic stretch-induced cell alignment in human airway smooth muscle cellsIntegrins and extracellular matrix in mechanotransductionTRPV channels and vascular functionPrevention of ventilator-induced lung edema by inhalation of nanoparticles releasing ruthenium red.Microfluidic control of axonal guidance.Microstructure and mechanics of human resistance arteriesIntegrins in development and cancer.TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress.Cyclic mechanical stretch decreases cell migration by inhibiting phosphatidylinositol 3-kinase- and focal adhesion kinase-mediated JNK1 activation.Transient receptor potential channels and regulation of lung endothelial permeability.Increased basal activity is a key determinant in the severity of human skeletal dysplasia caused by TRPV4 mutationsActomyosin tension exerted on the nucleus through nesprin-1 connections influences endothelial cell adhesion, migration, and cyclic strain-induced reorientation.Actin cytoskeleton regulates stretch-activated Ca2+ influx in human pulmonary microvascular endothelial cells.Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force.Role of MMP2 and MMP9 in TRPV4-induced lung injury.Transient receptor potential channel activation and endothelium-dependent dilation in the systemic circulation.Akt directly regulates focal adhesion kinase through association and serine phosphorylation: implication for pressure-induced colon cancer metastasis.The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cellsTRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice.Shear stress mediates exocytosis of functional TRPV4 channels in endothelial cells.Fluid flows and forces in development: functions, features and biophysical principles.PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells.Distribution and expression of non-neuronal transient receptor potential (TRPV) ion channels in rosaceaActivation of endothelial TRPV4 channels mediates flow-induced dilation in human coronary arterioles: role of Ca2+ entry and mitochondrial ROS signaling.Transient receptor potential channels in the vasculature.Caudal migration and proliferation of renal progenitors regulates early nephron segment size in zebrafishUpdate on vascular endothelial Ca(2+) signalling: A tale of ion channels, pumps and transportersMatrix Metalloproteinases as Regulators of Vein Structure and Function: Implications in Chronic Venous Disease.Human lung on a chip: innovative approach for understanding disease processes and effective drug testing
P2860
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P2860
TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
TRPV4 channels mediate cyclic ...... integrin-to-integrin signaling
@ast
TRPV4 channels mediate cyclic ...... integrin-to-integrin signaling
@en
type
label
TRPV4 channels mediate cyclic ...... integrin-to-integrin signaling
@ast
TRPV4 channels mediate cyclic ...... integrin-to-integrin signaling
@en
prefLabel
TRPV4 channels mediate cyclic ...... integrin-to-integrin signaling
@ast
TRPV4 channels mediate cyclic ...... integrin-to-integrin signaling
@en
P2093
P2860
P1433
P1476
TRPV4 channels mediate cyclic ...... integrin-to-integrin signaling
@en
P2093
Abigail L Bracha
Arvind Ravi
Benjamin Matthews
Charles K Thodeti
Kaustabh Ghosh
P2860
P304
P356
10.1161/CIRCRESAHA.108.192930
P577
2009-04-09T00:00:00Z