Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force. - Wikidata - wikimedia - TriplyDB

Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force.

Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force.

http://www.wikidata.org/entity/Q34094517

about

Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system From mechanosensitivity to inflammatory responses: new players in the pathology of glaucoma TRP channels and analgesia Genetically targeted magnetic control of the nervous system TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye.Mechanically Activated Ion Channels Differential Contribution of TRPA1, TRPV4 and TRPM8 to Colonic Nociception in Mice Feeling the hidden mechanical forces in lipid bilayer is an original sense Gain-of-function mutation in TRPV4 identified in patients with osteonecrosis of the femoral head Polymodal Sensory Integration in Retinal Ganglion Cells.TRPV channels and vascular function The puzzle of TRPV4 channelopathies.Functional role for Piezo1 in stretch-evoked Ca²⁺ influx and ATP release in urothelial cell cultures.Increased basal activity is a key determinant in the severity of human skeletal dysplasia caused by TRPV4 mutations TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Müller Glia.Swelling and eicosanoid metabolites differentially gate TRPV4 channels in retinal neurons and glia Mutant TRPV4-mediated toxicity is linked to increased constitutive function in axonal neuropathies.The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells L596-W733 bond between the start of the S4-S5 linker and the TRP box stabilizes the closed state of TRPV4 channel.Stochastic model of endothelial TRPV4 calcium sparklets: effect of bursting and cooperativity on EDH.Expression and characterization of the bacterial mechanosensitive channel MscS in Xenopus laevis oocytes The core domain as the force sensor of the yeast mechanosensitive TRP channel.Membrane potential and Ca2+ concentration dependence on pressure and vasoactive agents in arterial smooth muscle: A model.PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells.A channelopathy mechanism revealed by direct calmodulin activation of TrpV4.Pressure-dependent regulation of Ca2+ signalling in the vascular endothelium Human skeletal dysplasia caused by a constitutive activated transient receptor potential vanilloid 4 (TRPV4) cation channel mutation.Mechanosensitive TRPC1 channels promote calpain proteolysis of talin to regulate spinal axon outgrowth 4α-phorbol 12,13-didecanoate activates cultured mouse dorsal root ganglia neurons independently of TRPV4 Differential volume regulation and calcium signaling in two ciliary body cell types is subserved by TRPV4 channels.Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli.TRPC5 channels participate in pressure-sensing in aortic baroreceptors.A competing hydrophobic tug on L596 to the membrane core unlatches S4-S5 linker elbow from TRP helix and allows TRPV4 channel to open.Roles of ion transport in control of cell motility.The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements.TRPV4 Stimulation Induced Melatonin Secretion by Increasing Arylalkymine N-acetyltransferase (AANAT) Protein Level.Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes.Yeast luminometric and Xenopus oocyte electrophysiological examinations of the molecular mechanosensitivity of TRPV4.The Role of Mitochondria, Oxidative Stress, and the Radical-binding Protein A1M in Cultured Porcine Retina.Mechanosensitive Ion Channels in Cardiovascular Physiology

P2860

Q24627020-B4B9BAC0-1624-40A4-8669-E90FC79F9EF1 Q26864408-D430A11F-CB27-418D-B3D4-FA3E9A442A25 Q27021608-101CFFCB-3786-460D-B1EA-69A9C7404460 Q27311506-E07F0D3E-1F32-4FED-9F0B-8AAC7F3B966E Q27321772-6EFBCFCE-E051-4968-A072-0774F6CF9A96 Q28084779-E5BC9281-18A3-4F75-AA50-9C093CCFB5E9 Q28546749-FAB656F1-0E70-461B-B25B-A783CC60EB81 Q28658571-98DC4B0A-AE3A-4F2F-80C6-D53520F2CCD7 Q30276535-992411D3-8C47-4D89-A5C7-79CF968DFD2A Q30379818-56D5D7A9-27BB-4B85-B014-858A4DCC05BE Q30463988-FB22BD01-FC63-4ADC-9313-BE945A73EBB7 Q33355032-D93527AC-DFBF-4953-AB84-047A01782C20 Q33718595-86251E7A-2733-46E9-92B0-5B04B3ECFCFE Q33900735-91F3826E-ED8C-489E-96C8-F5960D2865F1 Q34496425-8B3B81CA-9D61-4349-89B0-164D22EC4FD6 Q34537097-5C210111-025F-476E-B586-F200C53563D4 Q34948196-69710716-3F28-4503-8068-A789A79552F4 Q35030683-A93B9032-A01D-489C-B417-E1FA2383E50D Q35212642-4B34C873-91AC-4187-8E05-5F98BDA5E7D3 Q35222026-80D6EC2C-FD2D-4ED8-BB6F-EB446DBD8162 Q35581369-58824986-C4A0-4EC1-A94E-39E6DA05B9FC Q35581381-AFA2429B-D022-4342-B919-9F23E47C4905 Q35795794-90080750-7B9D-4A3E-BE12-B6B52192000E Q35825876-512932B6-7A8B-4BB8-8373-16456F4DD7BC Q35910190-F62561BB-C52B-4D8E-8F78-E4EB7DF884DB Q36439959-1457FA5C-E057-41BF-B14D-E0063E5C0EC2 Q36514432-CF70D53D-B454-4046-BF3F-9E17D9403350 Q36515258-9C2C19D4-696E-4CE8-BDE5-2BA8C30BB320 Q36629305-54900CE6-8F28-437F-98E5-388E119E5750 Q36802497-2CA709CA-9AC6-435B-AEE9-6D35C207A06C Q36915448-0A4B197B-FBD4-4C4B-A63C-E908ABE036D9 Q37099484-11B3455F-0B09-4C9B-9C9D-ACB4DCAD160C Q37369327-9CE9363F-6B39-44F5-9AB5-3BE4C794CDD5 Q38110508-1BFA51DC-DE02-4896-B917-65A369B87446 Q38216887-86F6B3A2-1E5D-4F95-B8C8-DC0CCEE658B5 Q38709300-4BD9E781-EFD9-49FC-8116-0BEA36E578F1 Q38992046-F25AA425-8FDF-4955-913E-6D6EFDC9715E Q39630828-9BF3C5C7-1562-4724-B240-0640CB1519CC Q40360102-A1C3E561-5253-46FE-95AF-8802635191BF Q41609420-62B8F678-BE17-48DB-BD39-7FCC1697CF1F

P2860

Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force.

http://www.wikidata.org/entity/Q34094517

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Wild-type and brachyolmia-caus ...... ond directly to stretch force.

@ast

Wild-type and brachyolmia-caus ...... ond directly to stretch force.

@en

Wild-type and brachyolmia-caus ...... ond directly to stretch force.

@nl

type

label

Wild-type and brachyolmia-caus ...... ond directly to stretch force.

@ast

Wild-type and brachyolmia-caus ...... ond directly to stretch force.

@en

Wild-type and brachyolmia-caus ...... ond directly to stretch force.

@nl

prefLabel

Wild-type and brachyolmia-caus ...... ond directly to stretch force.

@ast

Wild-type and brachyolmia-caus ...... ond directly to stretch force.

@en

Wild-type and brachyolmia-caus ...... ond directly to stretch force.

@nl

P1433

Q34094517-BB223D61-21B2-441C-B16D-7AE7D85346B5

P1476

Q34094517-F9012062-9849-45C9-9654-0C9CC45AB8CB

P2093

Q34094517-1F7C7C83-B58C-4FCD-915F-675FBDED8DA4

Q34094517-57BF33C7-B424-426A-9641-56A636786CDB

Q34094517-7D86D924-FC7F-411B-A6F6-B025368B4CC9

Q34094517-D7E8AA38-C432-4570-A614-2D2681BD3C5B

Q34094517-DBE43828-2C2F-46AC-8BD5-574E03B724D2

P2860

Q34094517-0E8C9153-4BF8-4ADF-A382-32D77D40FBE2

Q34094517-18A17DE5-D7A7-4435-B8F0-28F51487A72B

Q34094517-3014C296-9AD0-4BDC-A81B-D020AA4167EA

Q34094517-35060CC4-75AD-496A-9E40-208BA325F7DF

Q34094517-407FC0F5-CB6F-4DF4-9A36-304286354CD6

Q34094517-43A6A7EF-766D-4CDD-A496-508D1C714512

Q34094517-4A95277E-DF62-4B81-89BA-59E6363A1CE6

Q34094517-4FAE7223-1FE9-483A-BF96-E904ABA83156

Q34094517-66628806-A5D0-42B7-BF4C-705BD1981F43

Q34094517-6BBFF8F7-3B52-40B2-8A41-C53F81CF585B

P304

Q34094517-A2484E7A-78F8-4C65-8BE3-8653B3ABD264

P31

Q34094517-E5837C13-960F-44FB-BB93-F41BD550494D

P356

Q34094517-21543C68-BC81-47AA-BE50-BF53C9ED53BB

P407

Q34094517-30E381CE-05FC-4526-9A77-5E00D1E764F6

P433

Q34094517-F694AB48-5671-4CB7-A438-1250A1DE4681

P478

Q34094517-82B0B680-8CC5-4B26-8D78-2914430E17FD

P577

Q34094517-0B59EE3A-C087-4378-A7D1-A2B0083CEBD3

P698

Q34094517-B5A5AD57-8C3A-45C1-851B-04F0C68FC3E4

P932

Q34094517-52E49F1B-C8DB-4492-A5A6-60F6AA6BED27

P356

JBC.M110.143370

P1433

Journal of Biological Chemistry

P1476

Wild-type and brachyolmia-caus ...... ond directly to stretch force.

@en

P2093

Ching Kung

http://www.w3.org/2001/XMLSchema#string

Stephen Loukin

http://www.w3.org/2001/XMLSchema#string

Xinliang Zhou

http://www.w3.org/2001/XMLSchema#string

Yoshiro Saimi

http://www.w3.org/2001/XMLSchema#string

Zhenwei Su

http://www.w3.org/2001/XMLSchema#string

P2860

A possible unifying principle for mechanosensation

OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity

TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity

Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor

Mechanically gated channel activity in cytoskeleton-deficient plasma membrane blebs and vesicles from Xenopus oocytes

TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling

TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells.

Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans

TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress.

Molecular and functional properties of two-pore-domain potassium channels.

P304

27176-27181

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M110.143370

http://www.w3.org/2001/XMLSchema#string

P407

P433

35

http://www.w3.org/2001/XMLSchema#string

P478

285

http://www.w3.org/2001/XMLSchema#string

P577

2010-07-06T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

20605796

http://www.w3.org/2001/XMLSchema#string

P932

2930716

http://www.w3.org/2001/XMLSchema#string