GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome - Wikidata - wikimedia - TriplyDB

GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome

GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome

http://www.wikidata.org/entity/Q30440683

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G protein-coupled receptors: extranuclear mediators for the non-genomic actions of steroids GPRC6A mediates the non-genomic effects of steroids.The L-Cell in Nutritional Sensing and the Regulation of Appetite New functional aspects of the extracellular calcium-sensing receptor Multiligand specificity and wide tissue expression of GPRC6A reveals new endocrine networks Minireview: Nutrient sensing by G protein-coupled receptors Bone as an endocrine organ Regulation of male fertility by the bone-derived hormone osteocalcin GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivo Obif, a Transmembrane Protein, Is Required for Bone Mineralization and Spermatogenesis in Mice Vitamin D and male reproduction Antagonizing effects of membrane-acting androgens on the eicosanoid receptor OXER1 in prostate cancer Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis.Novel bone endocrine networks integrating mineral and energy metabolism CRISPR/Cas9 targeting of GPRC6A suppresses prostate cancer tumorigenesis in a human xenograft model GPRC6A regulates prostate cancer progression Replication and fine mapping for association of the C2orf43, FOXP4, GPRC6A and RFX6 genes with prostate cancer in the Chinese population.Testosterone stimulates Duox1 activity through GPRC6A in skin keratinocytes Insulin secretion stimulated by L-arginine and its metabolite L-ornithine depends on Gα(i2)Endocrine regulation of male fertility by the skeleton.Impaired osteoblast function in GPRC6A null mice.GGCX and VKORC1 inhibit osteocalcin endocrine functions.The calcium-sensing receptor mediates bone turnover induced by dietary calcium and parathyroid hormone in neonates.Bone Regulates Glucose Metabolism as an Endocrine Organ through Osteocalcin.Skeleton and glucose metabolism: a bone-pancreas loop.The role of osteocalcin in human glucose metabolism: marker or mediator?Replication and cumulative effects of GWAS-identified genetic variations for prostate cancer in Asians: a case-control study in the ChinaPCa consortium.Relationship of testosterone and osteocalcin levels during growth Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants Structural and Functional Evidence for Testosterone Activation of GPRC6A in Peripheral Tissues New insights into the biology of osteocalcin.GPRC6a is not required for the effects of a high-protein diet on body weight in mice GPRC6A mediates the effects of L-arginine on insulin secretion in mouse pancreatic islets.Bone and Muscle Endocrine Functions: Unexpected Paradigms of Inter-organ Communication.Evidence for Osteocalcin Binding and Activation of GPRC6A in β-Cells The skeleton gets a (reproductive) life.L-arginine promotes gut hormone release and reduces food intake in rodents.Searching for additional endocrine functions of the skeleton: genetic approaches and implications for therapeutics.A systems biology preview of the relationships between mineral and metabolic complications in chronic kidney disease.In vivo analysis of the contribution of bone resorption to the control of glucose metabolism in mice

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GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome

http://www.wikidata.org/entity/Q30440683

description

2008 nî lūn-bûn

@nan

2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

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2008年论文

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name

GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome

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GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome

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GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome

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GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome

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GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome

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GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome

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JOURNAL.PONE.0003858

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GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome

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Benyi Li

http://www.w3.org/2001/XMLSchema#string

Brian Ringhofer

http://www.w3.org/2001/XMLSchema#string

Jianghong Zhang

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John J Harrington

http://www.w3.org/2001/XMLSchema#string

Junming Luo

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Kurt R Brunden

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Lane Christenson

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Ling Chen

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Min-Zhao Huang

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P David Jackson

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P2860

Aromatase expression and role of estrogens in male gonad : a review

Endocrine regulation of energy metabolism by the skeleton

The rat GPRC6A: cloning and characterization

Identification of a novel extracellular cation-sensing G-protein-coupled receptor

L-amino acid sensing by the extracellular Ca2+-sensing receptor

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor.

A PCR primer bank for quantitative gene expression analysis.

Generation and characterization of androgen receptor knockout (ARKO) mice: an in vivo model for the study of androgen functions in selective tissues.

Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids.

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e3858

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10.1371/JOURNAL.PONE.0003858

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12

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3

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L. Darryl Quarles

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2008-12-03T00:00:00Z

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23563796

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19050760

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metabolic syndrome

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2585477

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