A murine model of HUS: Shiga toxin with lipopolysaccharide mimics the renal damage and physiologic response of human disease.
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Shiga toxin 2 targets the murine renal collecting duct epitheliumShiga toxin 2 affects the central nervous system through receptor globotriaosylceramide localized to neurons.Modulation of neutrophil function by a secreted mucinase of Escherichia coli O157:H7Dexamethasone rescues neurovascular unit integrity from cell damage caused by systemic administration of shiga toxin 2 and lipopolysaccharide in mice motor cortexNatural killer T (NKT) cells accelerate Shiga toxin type 2 (Stx2) pathology in mice.Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model.Shiga toxin-mediated disease in MyD88-deficient mice infected with Escherichia coli O157:H7.p38 mitogen-activated protein kinase mediates lipopolysaccharide and tumor necrosis factor alpha induction of shiga toxin 2 sensitivity in human umbilical vein endothelial cellsMonocyte chemoattractant protein 1, macrophage inflammatory protein 1 alpha, and RANTES recruit macrophages to the kidney in a mouse model of hemolytic-uremic syndromeCXCL1/KC and CXCL2/MIP-2 are critical effectors and potential targets for therapy of Escherichia coli O157:H7-associated renal inflammation.Mouse model of hemolytic-uremic syndrome caused by endotoxin-free Shiga toxin 2 (Stx2) and protection from lethal outcome by anti-Stx2 antibody.Shiga toxin-2 results in renal tubular injury but not thrombotic microangiopathy in heterozygous factor H-deficient mice.Hemolytic uremic syndrome: pathogenesis and update of interventions.Globotriaosyl ceramide receptor function - where membrane structure and pathology intersect.Intestinal damage in enterohemorrhagic Escherichia coli infection.Advances in our understanding of the pathogenesis of glomerular thrombotic microangiopathy.Escherichia coli Shiga Toxin Mechanisms of Action in Renal Disease.Rescue from lethal Shiga toxin 2-induced renal failure with a cell-permeable peptide.Complement-mediated injury and protection of endothelium: lessons from atypical haemolytic uraemic syndromeShiga toxin pathogenesis: kidney complications and renal failure.The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome in humans and mice.Renal and neurological involvement in typical Shiga toxin-associated HUS.A novel murine infection model for Shiga toxin-producing Escherichia coli.Role of vascular endothelial growth factor and angiopoietin 1 in renal injury in hemolytic uremic syndrome.Shiga toxins and the pathophysiology of hemolytic uremic syndrome in humans and animals.Distinct renal pathology and a chemotactic phenotype after enterohemorrhagic Escherichia coli shiga toxins in non-human primate models of hemolytic uremic syndrome.Current evidence for the role of complement in the pathogenesis of Shiga toxin haemolytic uraemic syndrome.Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasomeRole of Shiga/Vero toxins in pathogenesisEffect of enterohaemorrhagic Escherichia coli O157:H7-specific enterohaemolysin on interleukin-1β production differs between human and mouse macrophages due to the different sensitivity of NLRP3 activation.The efficacy of recombinant human soluble thrombomodulin for the treatment of shiga toxin-associated hemolytic uremic syndrome model mice.Complement, thrombotic microangiopathy and disseminated intravascular coagulation.Human mannose-binding lectin inhibitor prevents Shiga toxin-induced renal injuryEscherichia coli O157:H7 infection in Dutch belted and New Zealand white rabbits.Global transcriptional response of macrophage-like THP-1 cells to Shiga toxin type 1Phenotypic expression of ADAMTS13 in glomerular endothelial cellsLipopolysaccharide renders transgenic mice expressing human serum amyloid P component sensitive to Shiga toxin 2Shiga toxin 2 and flagellin from shiga-toxigenic Escherichia coli superinduce interleukin-8 through synergistic effects on host stress-activated protein kinase activation.The ability of an attaching and effacing pathogen to trigger localized actin assembly contributes to virulence by promoting mucosal attachment.Role of tumor necrosis factor alpha in disease using a mouse model of Shiga toxin-mediated renal damage.
P2860
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P2860
A murine model of HUS: Shiga toxin with lipopolysaccharide mimics the renal damage and physiologic response of human disease.
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
A murine model of HUS: Shiga t ...... gic response of human disease.
@ast
A murine model of HUS: Shiga t ...... gic response of human disease.
@en
type
label
A murine model of HUS: Shiga t ...... gic response of human disease.
@ast
A murine model of HUS: Shiga t ...... gic response of human disease.
@en
prefLabel
A murine model of HUS: Shiga t ...... gic response of human disease.
@ast
A murine model of HUS: Shiga t ...... gic response of human disease.
@en
P2093
P356
P1476
A murine model of HUS: Shiga t ...... gic response of human disease.
@en
P2093
Lisa K Gross
Mitchell A Psotka
Tiffany R Keepers
Tom G Obrig
P304
P356
10.1681/ASN.2006050419
P577
2006-11-02T00:00:00Z