Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model.
about
Antibody to ricin a chain hinders intracellular routing of toxin and protects cells even after toxin has been internalizedBaicalin inhibits the lethality of ricin in mice by inducing protein oligomerization.A monoclonal immunoglobulin G antibody directed against an immunodominant linear epitope on the ricin A chain confers systemic and mucosal immunity to ricin.Neutralising antibodies against ricin toxin.Intradermal administration of RiVax protects mice from mucosal and systemic ricin intoxicationHumanization and characterization of an anti-ricin neutralization monoclonal antibodyAnimal models of ricin toxicosisProtective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB).Passive and active vaccination strategies to prevent ricin poisoning.Immunity to ricin: fundamental insights into toxin-antibody interactions.Plant-based expression of a partially humanized neutralizing monoclonal IgG directed against an immunodominant epitope on the ricin toxin A subunit.Pulmonary inflammation triggered by ricin toxin requires macrophages and IL-1 signalingClinical and Pathological Findings Associated with Aerosol Exposure of Macaques to Ricin ToxinLT-IIb(T13I), a non-toxic type II heat-labile enterotoxin, augments the capacity of a ricin toxin subunit vaccine to evoke neutralizing antibodies and protective immunityActivation of the cholinergic antiinflammatory pathway reduces ricin-induced mortality and organ failure in mice.Neutralizing activity and protective immunity to ricin toxin conferred by B subunit (RTB)-specific Fab fragmentsConformation-dependent high-affinity potent ricin-neutralizing monoclonal antibodies.Involvement of immune- and inflammatory-related factors in flucloxacillin-induced liver injury in mice.
P2860
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P2860
Post-exposure targeting of specific epitopes on ricin toxin abrogates toxin-induced hypoglycemia, hepatic injury, and lethality in a mouse model.
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Post-exposure targeting of spe ...... nd lethality in a mouse model.
@ast
Post-exposure targeting of spe ...... nd lethality in a mouse model.
@en
type
label
Post-exposure targeting of spe ...... nd lethality in a mouse model.
@ast
Post-exposure targeting of spe ...... nd lethality in a mouse model.
@en
prefLabel
Post-exposure targeting of spe ...... nd lethality in a mouse model.
@ast
Post-exposure targeting of spe ...... nd lethality in a mouse model.
@en
P2093
P2860
P1476
Post-exposure targeting of spe ...... nd lethality in a mouse model.
@en
P2093
James K Roche
Lisa K Gross
Matthew K Stone
Matthew Lindner
Regina Seaner
Seth H Pincus
Tom G Obrig
P2860
P2888
P304
P356
10.1038/LABINVEST.2008.83
P577
2008-09-08T00:00:00Z
P5875
P6179
1009288738