Toward understanding interfacial activation of secretory phospholipase A2 (PLA2): membrane surface properties and membrane-induced structural changes in the enzyme contribute synergistically to PLA2 activation
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Importance of Membrane Structural Integrity for RPE65 Retinoid Isomerization ActivityThe highly selective production of 2-arachidonoyl lysophosphatidylcholine catalyzed by purified calcium-independent phospholipase A2gamma: identification of a novel enzymatic mediator for the generation of a key branch point intermediate in eicosanoInfluence of product phase separation on phospholipase A(2) hydrolysis of supported phospholipid bilayers studied by force microscopy.Secondary structure, conformational stability and glycosylation of a recombinant Candida rugosa lipase studied by Fourier-transform infrared spectroscopy.Gossypol increases expression of the pro-apoptotic BH3-only protein NOXA through a novel mechanism involving phospholipase A2, cytoplasmic calcium, and endoplasmic reticulum stress.Structural effects of covalent inhibition of phospholipase A2 suggest allosteric coupling between membrane binding and catalytic sites.Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrin αvβ3.Ubiquitin activates patatin-like phospholipases from multiple bacterial speciesIdentification of novel inhibitors of Daboia russelli phospholipase A2 using the combined pharmacophore modeling approach.Relationship between membrane physical properties and secretory phospholipase A2 hydrolysis kinetics in S49 cells during ionophore-induced apoptosis.Quantitation of lysolipids, fatty acids, and phospholipase A2 activity and correlation with membrane polaritySequence of physical changes to the cell membrane during glucocorticoid-induced apoptosis in S49 lymphoma cells.Combining topographical and genetic cues to promote neuronal fate specification in stem cells.Amyloid-type fiber formation in control of enzyme action: interfacial activation of phospholipase A2Mechanisms governing the level of susceptibility of erythrocyte membranes to secretory phospholipase A2.The interaction of phospholipase A2 with a phospholipid bilayer: coarse-grained molecular dynamics simulations.Partitioning of lysolipids, fatty acids and their mixtures in aqueous lipid bilayers: solute concentration/composition effectsPro-inflammatory secretory phospholipase A2 type IIA binds to integrins alphavbeta3 and alpha4beta1 and induces proliferation of monocytic cells in an integrin-dependent manner.Kinetics of bacterial phospholipase C activity at micellar interfaces: effect of substrate aggregate microstructure and a model for the kinetic parameters.Different modulation of phospholipase A2 activity by saturated and monounsaturated N-acylethanolamines.Lipoprotein electrostatic properties regulate hepatic lipase association and activity.Calcium-dependent hydrolysis of supported planar lipids was triggered by honey bee venom phospholipase A2 with the right orientation at the interface.Characterization of Arabidopsis secretory phospholipase A2-gamma cDNA and its enzymatic properties.The phospholipid-repair system LplT/Aas in Gram-negative bacteria protects the bacterial membrane envelope from host phospholipase A2 attack.Secreted Phospholipase A2 Type IIA (sPLA2-IIA) Activates Integrins in an Allosteric Manner.Evidence for the regulatory role of the N-terminal helix of secretory phospholipase A(2) from studies on native and chimeric proteins.
P2860
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P2860
Toward understanding interfacial activation of secretory phospholipase A2 (PLA2): membrane surface properties and membrane-induced structural changes in the enzyme contribute synergistically to PLA2 activation
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
Toward understanding interfaci ...... rgistically to PLA2 activation
@ast
Toward understanding interfaci ...... rgistically to PLA2 activation
@en
type
label
Toward understanding interfaci ...... rgistically to PLA2 activation
@ast
Toward understanding interfaci ...... rgistically to PLA2 activation
@en
prefLabel
Toward understanding interfaci ...... rgistically to PLA2 activation
@ast
Toward understanding interfaci ...... rgistically to PLA2 activation
@en
P2860
P1433
P1476
Toward understanding interfaci ...... rgistically to PLA2 activation
@en
P2093
S A Tatulian
P2860
P304
P356
10.1016/S0006-3495(01)76058-4
P407
P577
2001-02-01T00:00:00Z