A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK
about
Systematic identification of regulatory proteins critical for T-cell activationA PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT.S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3Nckbeta adapter regulates actin polymerization in NIH 3T3 fibroblasts in response to platelet-derived growth factor bbVav-2 controls NFAT-dependent transcription in B- but not T-lymphocytesCdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascadeVav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathwaysMultiple interactions of the cytosolic polyproline region of the CD95 ligand: hints for the reverse signal transduction capacity of a death factorNuclear localization and chromatin targets of p21-activated kinase 1Deficiency of small GTPase Rac2 affects T cell activationNon-overlapping functions of Nck1 and Nck2 adaptor proteins in T cell activation.LAT-independent Erk activation via Bam32-PLC-γ1-Pak1 complexes: GTPase-independent Pak1 activation.Autoinhibitory interaction in the multidomain adaptor protein Nck: possible roles in improving specificity and functional diversity.Nck adapter proteins: functional versatility in T cellsPhosphatidylinositol 3-kinase p85 adaptor function in T-cells. Co-stimulation and regulation of cytokine transcription independent of associated p110.Nck/Dock: an adapter between cell surface receptors and the actin cytoskeleton.Abl family kinases and Cbl cooperate with the Nck adaptor to modulate Xenopus development.Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane."UnPAKing" human immunodeficiency virus (HIV) replication: using small interfering RNA screening to identify novel cofactors and elucidate the role of group I PAKs in HIV infectionSWAP-70-like adapter of T cells: a novel Lck-regulated guanine nucleotide exchange factor coordinating actin cytoskeleton reorganization and Ca2+ signaling in T cellsPak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation.Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation.Protein kinase C-η controls CTLA-4-mediated regulatory T cell function.P21-activated kinase in inflammatory and cardiovascular disease.Protein phosphatase 4 is a positive regulator of hematopoietic progenitor kinase 1.The transmembrane adapter LAT plays a central role in immune receptor signalling.Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP-76 and Vav1.Understanding Rho/Rac biology in T-cells using animal models.Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cellsA model of an integrated immune system pathway in Homo sapiens and its interaction with superantigen producing expression regulatory pathway in Staphylococcus aureus: comparing behavior of pathogen perturbed and unperturbed pathwayAll roads lead to actin: the intimate relationship between TCR signaling and the cytoskeleton.Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signalingmiR-155 Controls Lymphoproliferation in LAT Mutant Mice by Restraining T-Cell Apoptosis via SHIP-1/mTOR and PAK1/FOXO3/BIM PathwaysAntigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytesMaintenance and modulation of T cell polarity.Signal transduction in Alzheimer disease: p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664.Angioinhibitory action of NK4 involves impaired extracellular assembly of fibronectin mediated by perlecan-NK4 association.Ras and extracellular signal-regulated kinase signaling in thymocytes and T cells.p21-Activated protein kinases and their emerging roles in glucose homeostasis.
P2860
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P2860
A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
A Nck-Pak1 signaling module is ...... vation of NFAT, but not of JNK
@ast
A Nck-Pak1 signaling module is ...... vation of NFAT, but not of JNK
@en
type
label
A Nck-Pak1 signaling module is ...... vation of NFAT, but not of JNK
@ast
A Nck-Pak1 signaling module is ...... vation of NFAT, but not of JNK
@en
prefLabel
A Nck-Pak1 signaling module is ...... vation of NFAT, but not of JNK
@ast
A Nck-Pak1 signaling module is ...... vation of NFAT, but not of JNK
@en
P2093
P2860
P356
P1433
P1476
A Nck-Pak1 signaling module is ...... vation of NFAT, but not of JNK
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/17.19.5647
P407
P577
1998-10-01T00:00:00Z