Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity. - Wikidata - wikimedia - TriplyDB

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity.

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity.

http://www.wikidata.org/entity/Q30448692

about

Detailed mechanistic investigation into the S-nitrosation of cysteamine Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1 Parkin is an E3 ubiquitin-ligase for normal and mutant ataxin-2 and prevents ataxin-2-induced cell death ATF4 protects against neuronal death in cellular Parkinson's disease models by maintaining levels of parkin Programmed cell death-2 isoform1 is ubiquitinated by parkin and increased in the substantia nigra of patients with autosomal recessive Parkinson's disease Dopamine covalently modifies and functionally inactivates parkin Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling S-nitrosothiols signal hypoxia-mimetic vascular pathology Ubiquitin phosphorylation in Parkinson's disease: Implications for pathogenesis and treatment Redox control of protein degradation RBR E3 ubiquitin ligases: new structures, new insights, new questions Mechanisms of altered redox regulation in neurodegenerative diseases--focus on S--glutathionylation Molecular aspects of dopaminergic neurodegeneration: gene-environment interaction in parkin dysfunction Pathologic and therapeutic implications for the cell biology of parkin Roles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degeneration Structure of the Parkin in-between-ring domain provides insights for E3-ligase dysfunction in autosomal recessive Parkinson's disease Structure of parkin reveals mechanisms for ubiquitin ligase activation S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein C-Terminal Tyrosine Residue Modifications Modulate the Protective Phosphorylation of Serine 129 of α-Synuclein in a Yeast Model of Parkinson's Disease.14-3-3eta is a novel regulator of parkin ubiquitin ligase.S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson's disease alpha-Synuclein aggregates interfere with Parkin solubility and distribution: role in the pathogenesis of Parkinson disease The branched-chain aminotransferase proteins: novel redox chaperones for protein disulfide isomerase--implications in Alzheimer's disease NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration Gene-environment interactions: key to unraveling the mystery of Parkinson's disease iSNO-PseAAC: predict cysteine S-nitrosylation sites in proteins by incorporating position specific amino acid propensity into pseudo amino acid composition TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control The S-nitrosylation status of PCNA localized in cytosol impacts the apoptotic pathway in a Parkinson's disease paradigm iSNO-AAPair: incorporating amino acid pairwise coupling into PseAAC for predicting cysteine S-nitrosylation sites in proteins The effects of oxidative stress on parkin and other E3 ligases.ROSics: chemistry and proteomics of cysteine modifications in redox biology.Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases Endogenous S-nitrosoglutathione modifies 5-lipoxygenase expression in airway epithelial cells S-nitrosothiol depletion in amyotrophic lateral sclerosis.Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss.Role of the ubiquitin proteasome system in Parkinson's disease.Protein post-translational modifications: In silico prediction tools and molecular modeling.Parkin regulation of CHOP modulates susceptibility to cardiac endoplasmic reticulum stress.

P2860

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P2860

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity.

http://www.wikidata.org/entity/Q30448692

description

2004 nî lūn-bûn

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2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2004 թվականի հուլիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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name

Nitrosative stress linked to s ...... E3 ubiquitin ligase activity.

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Nitrosative stress linked to s ...... E3 ubiquitin ligase activity.

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Nitrosative stress linked to s ...... E3 ubiquitin ligase activity.

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Nitrosative stress linked to s ...... E3 ubiquitin ligase activity.

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PNAS.0404161101

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Proceedings of the National Academy of Sciences of the United States of America

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Nitrosative stress linked to s ...... E3 ubiquitin ligase activity.

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P2093

Benjamin Gaston

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Dongdong Yao

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Edward M Rockenstein

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Lisa A Palmer

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Stuart A Lipton

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Takashi Uehara

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Tomohiro Nakamura

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Yuliang Ma

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Zezong Gu

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Zhong-Qing Shi

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P2860

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function

Impairment of the ubiquitin-proteasome system by protein aggregation

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

Protein S-nitrosylation: a physiological signal for neuronal nitric oxide

Protein degradation and protection against misfolded or damaged proteins

Molecular pathways of neurodegeneration in Parkinson's disease

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10810-10814

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10.1073/PNAS.0404161101

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29

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101

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Eliezer Masliah

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2004-07-13T00:00:00Z

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8457686

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15252205

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Parkinson's disease

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490016

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