Identification and characterization of a gene that is coamplified with dihydrofolate reductase in a methotrexate-resistant CHO cell line
about
A potential role for mini-chromosome maintenance (MCM) proteins in initiation at the dihydrofolate reductase replication origin.The dihydrofolate reductase origin of replication does not contain any nonredundant genetic elements required for origin activity.The matrix attachment region in the Chinese hamster dihydrofolate reductase origin of replication may be required for local chromatid separation.Specific signals at the 3' end of the DHFR gene define one boundary of the downstream origin of replication.Activation of a mammalian origin of replication by chromosomal rearrangement.Replication initiation sites are distributed widely in the amplified CHO dihydrofolate reductase domain.Multiple origins of replication in the dihydrofolate reductase amplicons of a methotrexate-resistant chinese hamster cell line.The Chinese hamster dihydrofolate reductase origin consists of multiple potential nascent-strand start sitesTranscripts from amplified sequences of an inherited homogeneously staining region in chromosome 1 of the house mouse (Mus musculus)The mosquito dihydrofolate reductase amplicon contains a truncated synaptic vesicle protein gene.
P2860
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P2860
Identification and characterization of a gene that is coamplified with dihydrofolate reductase in a methotrexate-resistant CHO cell line
description
1989 nî lūn-bûn
@nan
1989 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի մարտին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Identification and characteriz ...... rexate-resistant CHO cell line
@ast
Identification and characteriz ...... rexate-resistant CHO cell line
@en
type
label
Identification and characteriz ...... rexate-resistant CHO cell line
@ast
Identification and characteriz ...... rexate-resistant CHO cell line
@en
prefLabel
Identification and characteriz ...... rexate-resistant CHO cell line
@ast
Identification and characteriz ...... rexate-resistant CHO cell line
@en
P2860
P356
P1476
Identification and characteriz ...... rexate-resistant CHO cell line
@en
P2093
J L Hamlin
P K Foreman
P2860
P304
P356
10.1128/MCB.9.3.1137
P407
P577
1989-03-01T00:00:00Z