The Chinese hamster dihydrofolate reductase origin consists of multiple potential nascent-strand start sites
about
Making sense of eukaryotic DNA replication origins.Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cyclePeaks cloaked in the mist: the landscape of mammalian replication originsHow MCM loading and spreading specify eukaryotic DNA replication initiation sitesA potential role for mini-chromosome maintenance (MCM) proteins in initiation at the dihydrofolate reductase replication origin.Initiation sites are distributed at frequent intervals in the Chinese hamster dihydrofolate reductase origin of replication but are used with very different efficienciesThe dihydrofolate reductase origin of replication does not contain any nonredundant genetic elements required for origin activity.The matrix attachment region in the Chinese hamster dihydrofolate reductase origin of replication may be required for local chromatid separation.The promoter of the Chinese hamster ovary dihydrofolate reductase gene regulates the activity of the local origin and helps define its boundariesCdc45 limits replicon usage from a low density of preRCs in mammalian cellsA winding road to origin discoveryTemporal profile of replication of human chromosomesSpecific signals at the 3' end of the DHFR gene define one boundary of the downstream origin of replication.Chromosome architecture can dictate site-specific initiation of DNA replication in Xenopus egg extracts.Characterizing replication intermediates in the amplified CHO dihydrofolate reductase domain by two novel gel electrophoretic techniques.Composite patterns in neutral/neutral two-dimensional gels demonstrate inefficient replication origin usage.Lagging-strand, early-labelling, and two-dimensional gel assays suggest multiple potential initiation sites in the Chinese hamster dihydrofolate reductase originA p53-independent damage-sensing mechanism that functions as a checkpoint at the G1/S transition in Chinese hamster ovary cells.Sequence and context effects on origin function in mammalian cells.Temporally coordinated assembly and disassembly of replication factories in the absence of DNA synthesisMechanism of chromosomal DNA replication initiation and replication fork stabilization in eukaryotes.Global regulation of genome duplication in eukaryotes: an overview from the epifluorescence microscope.Identification of primary initiation sites for DNA replication in the hamster dihydrofolate reductase gene initiation zone.Transformation abrogates an early G1-phase arrest point required for specification of the Chinese hamster DHFR replication origin.AT-rich region and repeated sequences - the essential elements of replication origins of bacterial replicons.Developmental changes in the Sciara II/9A initiation zone for DNA replication.Analysis of stress-induced duplex destabilization (SIDD) properties of replication origins, genes and intergenes in the fission yeast, Schizosaccharomyces pombeUtilization of the same DNA replication origin by human cells of different derivationReplication initiation and elongation fork rates within a differentially expressed human multicopy locus in early S phasePre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zoneTrapping DNA replication origins from the human genomeGenome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features.The hunt for origins of DNA replication in multicellular eukaryotesMapping of Replication Origins in the X Inactivation Center of Vole Microtus levis Reveals Extended Replication Initiation ZoneDNA replication and progression through S phase.High-resolution mapping of the origin of DNA replication in the hamster dihydrofolate reductase gene domain by competitive PCR.Active mammalian replication origins are associated with a high-density cluster of mCpG dinucleotides.The replication origin decision point is a mitogen-independent, 2-aminopurine-sensitive, G1-phase event that precedes restriction point control.Identifying a property of origins of DNA synthesis required to support plasmids stably in human cells.High-resolution analysis of DNA synthesis start sites and nucleosome architecture at efficient mammalian replication origins.
P2860
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P2860
The Chinese hamster dihydrofolate reductase origin consists of multiple potential nascent-strand start sites
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The Chinese hamster dihydrofol ...... ial nascent-strand start sites
@ast
The Chinese hamster dihydrofol ...... ial nascent-strand start sites
@en
type
label
The Chinese hamster dihydrofol ...... ial nascent-strand start sites
@ast
The Chinese hamster dihydrofol ...... ial nascent-strand start sites
@en
prefLabel
The Chinese hamster dihydrofol ...... ial nascent-strand start sites
@ast
The Chinese hamster dihydrofol ...... ial nascent-strand start sites
@en
P2860
P356
P1476
The Chinese hamster dihydrofol ...... ial nascent-strand start sites
@en
P2093
J L Hamlin
P A Dijkwel
P2860
P304
P356
10.1128/MCB.15.6.3023
P407
P577
1995-06-01T00:00:00Z