Isolation and partial characterization of a monoclonal antibody to the Rous sarcoma virus transforming protein pp60src.
about
Amino acid alterations within a highly conserved region of the Rous sarcoma virus src gene product pp60src inactivate tyrosine protein kinase activity.Inhibition of the tyrosine kinase activity of v-src, v-fgr, and v-yes gene products by a monoclonal antibody which binds both amino and carboxy peptide fragments of pp60v-src.Localization of conserved and nonconserved epitopes within the Rous sarcoma virus-encoded src protein.Rous sarcoma virus variants that encode src proteins with an altered carboxy terminus are defective for cellular transformation.Altered processing of a major secreted phosphoprotein correlates with tumorigenicity in Rous sarcoma virus-transformed mammalian cells.Monoclonal antibodies to Rous sarcoma virus pp60src react with enzymatically active cellular pp60src of avian and mammalian origin.Site-directed point mutation in the src gene oF rous sarcoma virus results in an inactive src gene product.Development and characterization of antisera specific for amino- and carboxy-terminal regions of pp60src.Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma virusesIsolation of monoclonal antibodies specific for products of avian oncogene myb.Forms of pp60v-src isolated from Rous sarcoma virus-transformed cells.
P2860
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P2860
Isolation and partial characterization of a monoclonal antibody to the Rous sarcoma virus transforming protein pp60src.
description
1983 nî lūn-bûn
@nan
1983 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1983 թվականի մարտին հրատարակված գիտական հոդված
@hy
1983年の論文
@ja
1983年論文
@yue
1983年論文
@zh-hant
1983年論文
@zh-hk
1983年論文
@zh-mo
1983年論文
@zh-tw
1983年论文
@wuu
name
Isolation and partial characte ...... transforming protein pp60src.
@ast
Isolation and partial characte ...... transforming protein pp60src.
@en
type
label
Isolation and partial characte ...... transforming protein pp60src.
@ast
Isolation and partial characte ...... transforming protein pp60src.
@en
prefLabel
Isolation and partial characte ...... transforming protein pp60src.
@ast
Isolation and partial characte ...... transforming protein pp60src.
@en
P2093
P2860
P1433
P1476
Isolation and partial characte ...... s transforming protein pp60src
@en
P2093
D C Benjamin
D J McCarley
J T Parsons
S J Parsons
P2860
P304
P577
1983-03-01T00:00:00Z