Mapping of replication initiation sites in mammalian genomes by two-dimensional gel analysis: stabilization and enrichment of replication intermediates by isolation on the nuclear matrix.
about
The origin of a developmentally regulated Igh replicon is located near the border of regulatory domains for Igh replication and expressionEvidence for rolling circle replication of tandem genes in DrosophilaMcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins.Interactions between Mcm10p and other replication factors are required for proper initiation and elongation of chromosomal DNA replication in Saccharomyces cerevisiae.A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae.Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis.A potential role for mini-chromosome maintenance (MCM) proteins in initiation at the dihydrofolate reductase replication origin.Initiation sites are distributed at frequent intervals in the Chinese hamster dihydrofolate reductase origin of replication but are used with very different efficienciesThe dihydrofolate reductase origin of replication does not contain any nonredundant genetic elements required for origin activity.The matrix attachment region in the Chinese hamster dihydrofolate reductase origin of replication may be required for local chromatid separation.Initiation of replication in the Chinese hamster dihydrofolate reductase domain.Mammalian origins of replication.The plant amino acid mimosine may inhibit initiation at origins of replication in Chinese hamster cells.The promoter of the Chinese hamster ovary dihydrofolate reductase gene regulates the activity of the local origin and helps define its boundariesBubble-seq analysis of the human genome reveals distinct chromatin-mediated mechanisms for regulating early- and late-firing origins.Bubble-chip analysis of human origin distributions demonstrates on a genomic scale significant clustering into zones and significant association with transcription.A winding road to origin discoveryGenomic study of replication initiation in human chromosomes reveals the influence of transcription regulation and chromatin structure on origin selection.Activation of a mammalian origin of replication by chromosomal rearrangement.Replication initiation sites are distributed widely in the amplified CHO dihydrofolate reductase domain.Radiation effects on DNA synthesis in a defined chromosomal replicon.A general protocol for evaluating the specific effects of DNA replication inhibitors.Characterizing replication intermediates in the amplified CHO dihydrofolate reductase domain by two novel gel electrophoretic techniques.Composite patterns in neutral/neutral two-dimensional gels demonstrate inefficient replication origin usage.The Chinese hamster dihydrofolate reductase origin consists of multiple potential nascent-strand start sitesRadiation down-regulates replication origin activity throughout the S phase in mammalian cells.Lagging-strand, early-labelling, and two-dimensional gel assays suggest multiple potential initiation sites in the Chinese hamster dihydrofolate reductase originAttachment to the nuclear matrix mediates specific alterations in chromatin structure.A p53-independent damage-sensing mechanism that functions as a checkpoint at the G1/S transition in Chinese hamster ovary cells.Sequence and context effects on origin function in mammalian cells.A comprehensive genome-wide map of autonomously replicating sequences in a naive genome.Prominent mitochondrial DNA recombination intermediates in human heart muscle.Targeted destruction of DNA replication protein Cdc6 by cell death pathways in mammals and yeast.Eukaryotic DNA replication.Extragenomic double-stranded DNA circles in yeast with linear mitochondrial genomes: potential involvement in telomere maintenance.Chromosomal replication initiates and terminates at random sequences but at regular intervals in the ribosomal DNA of Xenopus early embryosCancer-associated missplicing of exon 4 influences the subnuclear distribution of the DNA replication factor CIZ1.Modular structural elements in the replication origin region of Tetrahymena rDNA.Replication fork stalling by bulky DNA damage: localization at active origins and checkpoint modulationModular sequence elements associated with origin regions in eukaryotic chromosomal DNA.
P2860
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P2860
Mapping of replication initiation sites in mammalian genomes by two-dimensional gel analysis: stabilization and enrichment of replication intermediates by isolation on the nuclear matrix.
description
1991 nî lūn-bûn
@nan
1991 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Mapping of replication initiat ...... olation on the nuclear matrix.
@ast
Mapping of replication initiat ...... olation on the nuclear matrix.
@en
type
label
Mapping of replication initiat ...... olation on the nuclear matrix.
@ast
Mapping of replication initiat ...... olation on the nuclear matrix.
@en
prefLabel
Mapping of replication initiat ...... olation on the nuclear matrix.
@ast
Mapping of replication initiat ...... olation on the nuclear matrix.
@en
P2093
P2860
P356
P1476
Mapping of replication initiat ...... olation on the nuclear matrix.
@en
P2093
J L Hamlin
J P Vaughn
P A Dijkwel
P2860
P304
P356
10.1128/MCB.11.8.3850
P407
P577
1991-08-01T00:00:00Z