Cell-surface cytokeratin 8 is the major plasminogen receptor on breast cancer cells and is required for the accelerated activation of cell-associated plasminogen by tissue-type plasminogen activator.
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New Insight on the Role of Plasminogen Receptor in Cancer ProgressionCytokeratin 8 ectoplasmic domain binds urokinase-type plasminogen activator to breast tumor cells and modulates their adhesion, growth and invasiveness.Identification of cytokeratin 1 as a binding protein and presentation receptor for kininogens on endothelial cellsKeratin 8 expression in head and neck epithelia.Overexpression of cell surface cytokeratin 8 in multidrug-resistant MCF-7/MX cells enhances cell adhesion to the extracellular matrix.The cytoskeleton of digestive epithelia in health and disease.Group B streptococci and other gram-positive cocci bind to cytokeratin 8.Cellular strategies for proteolytic targeting during migration and invasion.Cleavage of host keratin 8 by a Chlamydia-secreted protease.Binding of TS1, an anti-keratin 8 antibody, in small-cell lung cancer after 177Lu-DOTA-Tyr3-octreotate treatment: a histological study in xenografted mice.Plasminogen binding and activation at the breast cancer cell surface: the integral role of urokinase activity.EpCAM-Independent Enrichment of Circulating Tumor Cells in Metastatic Breast Cancer.Increased plasminogen binding is associated with metastatic breast cancer cells: differential expression of plasminogen binding proteinsProteomic definition of normal human luminal and myoepithelial breast cells purified from reduction mammoplasties.Keratin mediates the recognition of apoptotic and necrotic cells through dendritic cell receptor DEC205/CD205.α-Enolase: a promising therapeutic and diagnostic tumor target.α-Enolase, a multifunctional protein: its role on pathophysiological situationsThree are better than one: plasminogen receptors as cancer theranostic targets.From plasminogen to plasmin: role of plasminogen receptors in human cancer.Detection of large molecular weight cytokeratin 8 as carrier protein of CA19-9 in non-small-cell lung cancer cell linesKringle 2 mediates high affinity binding of plasminogen to an internal sequence in streptococcal surface protein PAM.Prostate cancer cell surface-associated keratin 8 and its implications for enhanced plasmin activity.Widespread, exceptionally high levels of histone H3 lysine 4 trimethylation largely mediate "privileged" gene expression.Annexin A2-S100A10 heterotetramer, a novel substrate of thioredoxin.Specific interaction of tissue-type plasminogen activator (t-PA) with annexin II on the membrane of pancreatic cancer cells activates plasminogen and promotes invasion in vitro.RNA interference-mediated silencing of the S100A10 gene attenuates plasmin generation and invasiveness of Colo 222 colorectal cancer cells.Infection by Trypanosoma cruzi. Identification of a parasite ligand and its host cell receptor.Allele-specific recognition by LILRB3 and LILRA6 of a cytokeratin 8-associated ligand on necrotic glandular epithelial cells.Expression pattern of the plasminogen activator-plasmin system in human cholesteatoma.Epsilon-aminocaproic acid prevents high glucose and insulin induced-invasiveness in MDA-MB-231 breast cancer cells, modulating the plasminogen activator system.Nuclear Localization of Cytokeratin 8 and the O-linkedN-Acetylglucosamine-containing Epitope H in Epithelial Cells of Infiltrating Ductal Breast Carcinomas: A Combination of Immunogold and EDTA Regressive Staining Methods
P2860
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P2860
Cell-surface cytokeratin 8 is the major plasminogen receptor on breast cancer cells and is required for the accelerated activation of cell-associated plasminogen by tissue-type plasminogen activator.
description
1996 nî lūn-bûn
@nan
1996 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
name
Cell-surface cytokeratin 8 is ...... ue-type plasminogen activator.
@ast
Cell-surface cytokeratin 8 is ...... ue-type plasminogen activator.
@en
type
label
Cell-surface cytokeratin 8 is ...... ue-type plasminogen activator.
@ast
Cell-surface cytokeratin 8 is ...... ue-type plasminogen activator.
@en
prefLabel
Cell-surface cytokeratin 8 is ...... ue-type plasminogen activator.
@ast
Cell-surface cytokeratin 8 is ...... ue-type plasminogen activator.
@en
P2093
P356
P1476
Cell-surface cytokeratin 8 is ...... ue-type plasminogen activator.
@en
P2093
P304
25684-25691
P356
10.1074/JBC.271.41.25684
P407
P577
1996-10-01T00:00:00Z