Specific interaction of tissue-type plasminogen activator (t-PA) with annexin II on the membrane of pancreatic cancer cells activates plasminogen and promotes invasion in vitro. - Wikidata - wikimedia - TriplyDB

Specific interaction of tissue-type plasminogen activator (t-PA) with annexin II on the membrane of pancreatic cancer cells activates plasminogen and promotes invasion in vitro.

Specific interaction of tissue-type plasminogen activator (t-PA) with annexin II on the membrane of pancreatic cancer cells activates plasminogen and promotes invasion in vitro.

http://www.wikidata.org/entity/Q40503987

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Biomarkers for the early diagnosis of hepatocellular carcinoma DNA methylation and microRNA dysregulation in cancer Molecularly and clinically related drugs and diseases are enriched in phenotypically similar drug-disease pairs A functional proteomic method for biomarker discovery.Proteomic characterization of harvested pseudopodia with differential gel electrophoresis and specific antibodies.Dysfunction of annexin A2 contributes to hyperglycaemia-induced loss of human endothelial cell surface fibrinolytic activity Reciprocal regulation of annexin A2 and EGFR with Her-2 in Her-2 negative and herceptin-resistant breast cancer Secretory leukocyte protease inhibitor (SLPI) expression and tumor invasion in oral squamous cell carcinoma Gene expression profile during chondrogenesis in human bone marrow derived mesenchymal stem cells using a cDNA microarray.ERG oncoprotein inhibits ANXA2 expression and function in prostate cancer Under-expression of annexin A2 is associated with Kazakh's esophageal squamous cell carcinoma.Annexin A2 promotes glioma cell invasion and tumor progression Clathrin mediates endocytosis of progastrin and activates MAPKs: role of cell surface annexin A2.Role of Annexin-II in GI cancers: interaction with gastrins/progastrins.Progastrin overexpression imparts tumorigenic/metastatic potential to embryonic epithelial cells: phenotypic differences between transformed and nontransformed stem cells.Upregulated expression of annexin II is a prognostic marker for patients with gastric cancer.Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis Characterisation and protein expression profiling of annexins in colorectal cancer.Annexin A2 heterotetramer: structure and function Increased annexin A1 and A2 levels in bronchoalveolar lavage fluid are associated with resistance to respiratory disease in beef calves.Tyrosine 23 Phosphorylation of Annexin A2 Promotes Proliferation, Invasion, and Stat3 Phosphorylation in the Nucleus of Human Breast Cancer SK-BR-3 Cells.Annexin A2 is regulated by ovarian cancer-peritoneal cell interactions and promotes metastasis.Annexin II represents metastatic potential in clear-cell renal cell carcinoma.Annexin A2: its molecular regulation and cellular expression in cancer development.Annexin A2 complexes with S100 proteins: structure, function and pharmacological manipulation.The role of annexin A2 in tumorigenesis and cancer progression Proteins from formalin-fixed paraffin-embedded prostate cancer sections that predict the risk of metastatic disease.PRRX2 as a novel TGF-β-induced factor enhances invasion and migration in mammary epithelial cell and correlates with poor prognosis in breast cancer.Biological characteristics of a novel giant cell tumor cell line derived from spine.Annexin 2A sustains glioblastoma cell dissemination and proliferation.Cationic lipid guided short-hairpin RNA interference of annexin A2 attenuates tumor growth and metastasis in a mouse lung cancer stem cell model Proteomics-based analysis of invasion-related proteins in malignant gliomas.Clinical and prognostic role of annexin A2 in adamantinomatous craniopharyngioma.Annexin II/annexin II receptor axis regulates adhesion, migration, homing, and growth of prostate cancer.Annexin A2 is a molecular target for TM601, a peptide with tumor-targeting and anti-angiogenic effects.Annexin A2 regulates the levels of plasmin, S100A10 and Fascin in L5178Y cells.Interferon-gamma reduces cell surface expression of annexin 2 and suppresses the invasive capacity of prostate cancer cells.Glycosylation and annexin II cell surface translocation mediate airway epithelial wound repair.Tissue plasminogen activator induces pancreatic cancer cell proliferation by a non-catalytic mechanism that requires extracellular signal-regulated kinase 1/2 activation through epidermal growth factor receptor and annexin A2.Activation of the epidermal growth factor signalling pathway by tissue plasminogen activator in pancreas cancer cells.

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P2860

Specific interaction of tissue-type plasminogen activator (t-PA) with annexin II on the membrane of pancreatic cancer cells activates plasminogen and promotes invasion in vitro.

http://www.wikidata.org/entity/Q40503987

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M Hurtado

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R Paciucci

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T M Thomson

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V M Díaz

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P2860

Interactions of plasminogen and tissue plasminogen activator (t-PA) with amphoterin. Enhancement of t-PA-catalyzed plasminogen activation by amphoterin

Elements of the fibrinolytic system

Cytokeratin 8 functions as a major plasminogen receptor in select epithelial and carcinoma cells.

Cell-surface cytokeratin 8 is the major plasminogen receptor on breast cancer cells and is required for the accelerated activation of cell-associated plasminogen by tissue-type plasminogen activator.

Characterization of the binding sites for plasminogen and tissue-type plasminogen activator in cytokeratin 8 and cytokeratin 18.

Functional regulation of tissue plasminogen activator on the surface of vascular smooth muscle cells by the type-II transmembrane protein p63 (CKAP4).

Plasminogen-mediated matrix invasion and degradation by macrophages is dependent on surface expression of annexin II.

Cell surface complex of cathepsin B/annexin II tetramer in malignant progression.

The plasminogen activation system in tumor growth, invasion, and metastasis.

Role of the matrix metalloproteinase and plasminogen activator-plasmin systems in angiogenesis.

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