Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status.
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Thiazolidinediones promote axonal growth through the activation of the JNK pathwayPPARγ as a therapeutic target to rescue mitochondrial function in neurological diseaseRole of anti-diabetic drugs as therapeutic agents in Alzheimer's diseaseInfluence of drug transporters and stereoselectivity on the brain penetration of pioglitazone as a potential medicine against Alzheimer's diseaseUsing genetics to enable studies on the prevention of Alzheimer's diseaseVascular and metabolic dysfunction in Alzheimer's disease: a review.Nuclear receptors in neurodegenerative diseases.Insulin resistance in Alzheimer's disease.IUGR disrupts the PPARγ-Setd8-H4K20me(1) and Wnt signaling pathways in the juvenile rat hippocampus.Activation of PPAR gamma receptors reduces levodopa-induced dyskinesias in 6-OHDA-lesioned rats.Nuclear receptors as therapeutic targets for Alzheimer's diseaseImpaired firing properties of dentate granule neurons in an Alzheimer's disease animal model are rescued by PPARγ agonism.The association of diabetes and dementia and possible implications for nondiabetic populations.Aging, synaptic dysfunction, and insulin-like growth factor (IGF)-1Long-term pioglitazone treatment improves learning and attenuates pathological markers in a mouse model of Alzheimer's diseaseCombined Liver X Receptor/Peroxisome Proliferator-activated Receptor γ Agonist Treatment Reduces Amyloid β Levels and Improves Behavior in Amyloid Precursor Protein/Presenilin 1 MiceMechanisms underlying the rapid peroxisome proliferator-activated receptor-γ-mediated amyloid clearance and reversal of cognitive deficits in a murine model of Alzheimer's disease.Cognitive enhancement with rosiglitazone links the hippocampal PPARγ and ERK MAPK signaling pathways.Time-dependent behavioral, neurochemical, and metabolic dysregulation in female C57BL/6 mice caused by chronic high-fat diet intake.Type 2 diabetes and cognitive compromise: potential roles of diabetes-related therapies.Targeting Alzheimer's Disease Neuro-Metabolic Dysfunction with a Small Molecule Nuclear Receptor Agonist (T3D-959) Reverses Disease Pathologies.Neuroprotective effects of sodium hydrosulfide against β-amyloid-induced neurotoxicity.Cognitive enhancing treatment with a PPARγ agonist normalizes dentate granule cell presynaptic function in Tg2576 APP mice.PPARγ recruitment to active ERK during memory consolidation is required for Alzheimer's disease-related cognitive enhancementA review: treatment of Alzheimer's disease discovered in repurposed agents.T3D-959: A Multi-Faceted Disease Remedial Drug Candidate for the Treatment of Alzheimer's Disease.Central insulin dysregulation and energy dyshomeostasis in two mouse models of Alzheimer's disease.PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease.Therapeutic potential of nuclear receptor agonists in Alzheimer's disease.Ruthenium red colorimetric and birefringent staining of amyloid-β aggregates in vitro and in Tg2576 miceInsulin receptor β-subunit haploinsufficiency impairs hippocampal late-phase LTP and recognition memory.Insulin sensitizers improve learning and attenuate tau hyperphosphorylation and neuroinflammation in 3xTg-AD mice.Central Regulation of Glucose Homeostasis.Research tool: Validation of floxed α7 nicotinic acetylcholine receptor conditional knockout mice using in vitro and in vivo approaches.The PPARγ agonist rosiglitazone prevents cognitive impairment by inhibiting astrocyte activation and oxidative stress following pilocarpine-induced status epilepticus.PPARγ agonism attenuates cocaine cue reactivity.Acute inhalation of combustion smoke triggers neuroinflammation and persistent anxiety-like behavior in the mouse.
P2860
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P2860
Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Rosiglitazone reversal of Tg25 ...... heral gluco-regulatory status.
@ast
Rosiglitazone reversal of Tg25 ...... heral gluco-regulatory status.
@en
type
label
Rosiglitazone reversal of Tg25 ...... heral gluco-regulatory status.
@ast
Rosiglitazone reversal of Tg25 ...... heral gluco-regulatory status.
@en
prefLabel
Rosiglitazone reversal of Tg25 ...... heral gluco-regulatory status.
@ast
Rosiglitazone reversal of Tg25 ...... heral gluco-regulatory status.
@en
P2093
P2860
P1476
Rosiglitazone reversal of Tg25 ...... heral gluco-regulatory status.
@en
P2093
Jennifer Rodriguez-Rivera
Kelly T Dineley
Larry Denner
P2860
P304
P356
10.1016/J.BBR.2010.08.002
P407
P577
2010-08-13T00:00:00Z