Knockdown of zebrafish Lgi1a results in abnormal development, brain defects and a seizure-like behavioral phenotype
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LGI proteins in the nervous system.Glutamatergic neuron-targeted loss of LGI1 epilepsy gene results in seizuresSeizures induced by pentylenetetrazole in the adult zebrafish: a detailed behavioral characterizationEpilepsy, Behavioral Abnormalities, and Physiological Comorbidities in Syntaxin-Binding Protein 1 (STXBP1) Mutant Zebrafish.Loss of zebrafish lgi1b leads to hydrocephalus and sensitization to pentylenetetrazol induced seizure-like behavior.The temporal and spatial expression pattern of the LGI1 epilepsy predisposition gene during mouse embryonic cranial development.Mechanisms of prickle1a function in zebrafish epilepsy and retinal neurogenesisSilencer-delimited transgenesis: NRSE/RE1 sequences promote neural-specific transgene expression in a NRSF/REST-dependent manner.Evaluating human cancer cell metastasis in zebrafish.Large-Scale Phenotype-Based Antiepileptic Drug Screening in a Zebrafish Model of Dravet Syndrome(1,2,3).Suppression of breast cancer metastasis through the inactivation of ADP-ribosylation factor 1.The promise of zebrafish as a chemical screening tool in cancer therapy.Genetic Discoveries Drive Molecular Analyses and Targeted Therapeutic Options in the Epilepsies.Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish.LGI1 tunes intrinsic excitability by regulating the density of axonal Kv1 channels.Zebrafish as a model to evaluate peptide-related cancer therapies.Zebrafish models in neuropsychopharmacology and CNS drug discovery.Recording the adult zebrafish cerebral field potential during pentylenetetrazole seizures.Pyridoxine-Dependent Epilepsy in Zebrafish Caused by Aldh7a1 Deficiency.Brain activity patterns in high-throughput electrophysiology screen predict both drug efficacies and side effects.Depdc5 knockdown causes mTOR-dependent motor hyperactivity in zebrafish.
P2860
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P2860
Knockdown of zebrafish Lgi1a results in abnormal development, brain defects and a seizure-like behavioral phenotype
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Knockdown of zebrafish Lgi1a r ...... zure-like behavioral phenotype
@ast
Knockdown of zebrafish Lgi1a r ...... zure-like behavioral phenotype
@en
type
label
Knockdown of zebrafish Lgi1a r ...... zure-like behavioral phenotype
@ast
Knockdown of zebrafish Lgi1a r ...... zure-like behavioral phenotype
@en
prefLabel
Knockdown of zebrafish Lgi1a r ...... zure-like behavioral phenotype
@ast
Knockdown of zebrafish Lgi1a r ...... zure-like behavioral phenotype
@en
P2093
P2860
P50
P356
P1476
Knockdown of zebrafish Lgi1a r ...... zure-like behavioral phenotype
@en
P2093
David J Kozlowski
Grzegorz Rempala
Steven Walker
Xiayang Xie
P2860
P304
P356
10.1093/HMG/DDQ364
P577
2010-09-06T00:00:00Z