A putative molecular-activation switch in the transmembrane domain of erbB2.
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ErbB2, EphrinB1, Src kinase and PTPN13 signaling complex regulates MAP kinase signaling in human cancersMechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segmentConformational coupling across the plasma membrane in activation of the EGF receptorCommon ERBB2 polymorphisms and risk of breast cancer in a white British population: a case-control studyA case-control study of the HER2 Ile655Val polymorphism in relation to risk of invasive breast cancerTen things you should know about protein kinases: IUPHAR Review 14Transmembrane helix dimerization: beyond the search for sequence motifsConformational Changes in the Epidermal Growth Factor Receptor: Role of the Transmembrane Domain Investigated by Coarse-Grained MetaDynamics Free Energy CalculationsSpatial Structure and pH-dependent Conformational Diversity of Dimeric Transmembrane Domain of the Receptor Tyrosine Kinase EphA1Left-Handed Dimer of EphA2 Transmembrane Domain: Helix Packing Diversity among Receptor Tyrosine KinasesBinding of MgtR, a Salmonella Transmembrane Regulatory Peptide, to MgtC, a Mycobacterium tuberculosis Virulence Factor: A Structural StudyTransmembrane recognition of the semaphorin co-receptors neuropilin 1 and plexin A1: coarse-grained simulationsMembrane interaction of bound ligands contributes to the negative binding cooperativity of the EGF receptorUnderstanding single-pass transmembrane receptor signaling from a structural viewpoint-what are we missing?An automatic method for predicting transmembrane protein structures using cryo-EM and evolutionary dataThe genetic polymorphisms of HER-2 and the risk of lung cancer in a Korean populationHER2 Pro1170Ala polymorphism is associated with decreased survival rate in HER2-negative breast cancerStructure elucidation of dimeric transmembrane domains of bitopic proteinsImpact of ERBB2 mutations on in vitro sensitivity of bladder cancer to lapatinib.The role of HER2 in cancer therapy and targeted drug deliveryActivation of transmembrane cell-surface receptors via a common mechanism? The "rotation model".The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesisFunctional polymorphisms associated with disease-free survival in resected carcinoma of the esophagus.Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies.Mechanisms of integral membrane protein insertion and foldingGxxxG motifs, phenylalanine, and cholesterol guide the self-association of transmembrane domains of ErbB2 receptorsN-Glycosylation as determinant of epidermal growth factor receptor conformation in membranes.Oncogenic HER2 fusions in gastric cancer.Regulation of the catalytic activity of the EGF receptor.A structural perspective on the regulation of the epidermal growth factor receptor.The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function.HER2 therapy. HER2 (ERBB2): functional diversity from structurally conserved building blocks.Phosphatidylinositol-4,5-bisphosphate regulates epidermal growth factor receptor activationSequence variants and haplotype analysis of cat ERBB2 gene: a survey on spontaneous cat mammary neoplastic and non-neoplastic lesions.Detection of HER2 Gene Polymorphism in Breast Cancer: PCR Optimization Study.Prediction, refinement, and persistency of transmembrane helix dimers in lipid bilayers using implicit and explicit solvent/lipid representations: microsecond molecular dynamics simulations of ErbB1/B2 and EphA1.HER2 Ile655Val Single Nucleotide Polymorphism in Patients with Ovarian Cancer.VEGFR-2 conformational switch in response to ligand binding.Architecture and membrane interactions of the EGF receptor.Molecular basis for multimerization in the activation of the epidermal growth factor receptor
P2860
Q24303562-7B1C3298-4D47-4A47-9E4E-D223A57068D9Q24309071-4E3701A4-29D6-4FDB-80E0-48493A6B98FDQ24313122-F1773B58-2400-4317-9621-16253B6FA0B2Q24797594-7BDDD23B-32C1-4F72-A158-F0402C62A4B4Q24810260-05B10AC4-8842-4B94-96E6-5ACA253FF3C2Q26849417-9700170E-D01E-494B-A346-E03A7D2A88C9Q26865109-E29BBC32-A453-4472-AA18-FFCEEBC35283Q27336007-B091CCA5-BDC2-4EF0-A8B5-47BE775032F5Q27651810-BD686263-D828-45F0-8AB1-B30103EFC9A8Q27660088-E10FF1DF-8237-4EEF-9B68-2B146390C9F1Q27680399-54846A4A-6AA5-46A4-8947-99A338DA9D9FQ28539091-EC9D8995-7712-47DB-857E-2E15CD90FABCQ28541111-2559C141-E096-421C-A71B-F3D4C2DBB0F1Q30389866-5BCB1D28-2AC5-4ADE-B0B3-19C0C4A2EE7CQ30955555-6947ED7F-8843-42E4-AD5D-F76BE6A39116Q33389608-1B77B84F-AEF3-4E28-838C-D15581E8432CQ33686182-6A145D7E-4324-49E8-8771-864899DB6DD9Q33977508-D8478F63-5CDC-48AA-BD8B-1778E0CADA24Q34028470-E5C9F8E9-38A3-449A-9044-FDCEA3F1F831Q34054213-D8C07B21-8227-4799-93BC-82CBBBC97C6FQ34488179-508F2AF4-40BB-49AD-B828-A9DCCEA084D9Q34493341-59FCF25E-34ED-4221-A1C7-6F27662767A0Q34500998-04E0548D-1531-4817-ABAA-9988E2DDE129Q34525985-7BD12834-DAB2-4A73-8037-619FD16EB2A7Q35118815-58DC8E4D-CF04-4A27-8C80-A6CD3005C680Q35342149-2B6C5230-237B-4B3E-B8E9-03DD18A3AFFCQ35378448-954331AC-DC20-4610-9A47-523531179267Q35414389-AC75E141-03B1-405D-9D1F-07AB298E7473Q35597077-6982AF77-78EC-4A71-A973-882620D32415Q35674768-A0A3C12D-E520-4E91-8124-DDF5AE340A49Q35729931-4275F150-05D9-4F08-A3AE-65EEA5DA49F5Q35749374-06399E16-CE8C-47A7-8921-3AB6E4C3A436Q35762279-5EDCDB3E-6DB6-4BEB-8365-5AB9A5BA7BC9Q35865954-4EC422AE-49F4-47CB-B9E5-CE284ED3835DQ35997942-03C54A80-E98A-46B0-9DDB-70287B8E00BFQ36569264-5B240614-F2E6-418A-BBE5-95D5F4FF8460Q36660906-C6899F7C-E2B7-4137-8F11-65237DBE4B9CQ36791927-C592CC56-1209-4929-A38E-2D9476ABD94EQ36923502-DFB60320-F762-48B5-B5AD-88CB7C01BACEQ36993693-6364097B-15A6-4B1E-8CB9-4D26A25CBB0A
P2860
A putative molecular-activation switch in the transmembrane domain of erbB2.
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A putative molecular-activation switch in the transmembrane domain of erbB2.
@ast
A putative molecular-activation switch in the transmembrane domain of erbB2.
@en
type
label
A putative molecular-activation switch in the transmembrane domain of erbB2.
@ast
A putative molecular-activation switch in the transmembrane domain of erbB2.
@en
prefLabel
A putative molecular-activation switch in the transmembrane domain of erbB2.
@ast
A putative molecular-activation switch in the transmembrane domain of erbB2.
@en
P2860
P50
P356
P1476
A putative molecular-activation switch in the transmembrane domain of erbB2.
@en
P2860
P304
15937-15940
P356
10.1073/PNAS.252640799
P407
P577
2002-12-02T00:00:00Z