Identification of novel non-hydroxamate anthrax toxin lethal factor inhibitors by topomeric searching, docking and scoring, and in vitro screening.

Identification of novel non-hydroxamate anthrax toxin lethal factor inhibitors by topomeric searching, docking and scoring, and in vitro screening.

Item
http://www.wikidata.org/entity/Q30478430
Computational methods in drug discoveryAnthrax toxin lethal factor domain 3 is highly mobile and responsive to ligand bindingDevelopment of a comprehensive, validated pharmacophore hypothesis for anthrax toxin lethal factor (LF) inhibitors using genetic algorithms, Pareto scoring, and structural biology.Small molecule inhibitors of Bacillus anthracis protective antigen proteolytic activation and oligomerization.Highly predictive support vector machine (SVM) models for anthrax toxin lethal factor (LF) inhibitors.Electrostatically Embedded Many-Body Expansion for Neutral and Charged Metalloenzyme Model SystemsInhibitors of the Metalloproteinase Anthrax Lethal Factor.Statistical analysis, optimization, and prioritization of virtual screening parameters for zinc enzymes including the anthrax toxin lethal factor.Identification of novel anthrax toxin countermeasures using in silico methods.Ligand-induced expansion of the S1' site in the anthrax toxin lethal factorSmall molecule inhibitors of anthrax lethal factor toxinModeling approaches for ligand-based 3D similarity.Development of antivirulence compounds: a biochemical review.Task-parallel message passing interface implementation of Autodock4 for docking of very large databases of compounds using high-performance super-computers.
P2860

Identification of novel non-hydroxamate anthrax toxin lethal factor inhibitors by topomeric searching, docking and scoring, and in vitro screening.

Item
http://www.wikidata.org/entity/Q30478430
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Identification of novel non-hy ...... oring, and in vitro screening.
@ast
Identification of novel non-hy ...... oring, and in vitro screening.
@en
type
label
Identification of novel non-hy ...... oring, and in vitro screening.
@ast
Identification of novel non-hy ...... oring, and in vitro screening.
@en
prefLabel
Identification of novel non-hy ...... oring, and in vitro screening.
@ast
Identification of novel non-hy ...... oring, and in vitro screening.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Identification of novel non-hy ...... oring, and in vitro screening.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932