Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus. - Wikidata - wikimedia - TriplyDB

Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus.

Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus.

http://www.wikidata.org/entity/Q30479942

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Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor Radiosensitization Clathrin-independent endocytosis of ErbB2 in geldanamycin-treated human breast cancer cells.The NF2 tumor suppressor regulates microtubule-based vesicle trafficking via a novel Rac, MLK and p38(SAPK) pathway.The HSP90 inhibitor geldanamycin perturbs endosomal structure and drives recycling ErbB2 and transferrin to modified MVBs/lysosomal compartments ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.Role of Erbin in ErbB2-dependent breast tumor growth.Geldanamycin selectively targets the nascent form of ERBB3 for degradation A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells.A heat-shock protein axis regulates VEGFR2 proteolysis, blood vessel development and repair.Chronic morphine treatment attenuates cell growth of human BT474 breast cancer cells by rearrangement of the ErbB signalling network.Endocytosis and intracellular trafficking of ErbBs.Mechanisms of Trastuzumab resistance in ErbB2-driven breast cancer and newer opportunities to overcome therapy resistance.HER2 signaling regulates HER2 localization and membrane retention.Endocytic downregulation of ErbB receptors: mechanisms and relevance in cancer A combination of two antibodies recognizing non-overlapping epitopes of HER2 induces kinase activity-dependent internalization of HER2.Enhanced internalization of ErbB2 in SK-BR-3 cells with multivalent forms of an artificial ligand Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins Septins: Regulators of Protein Stability.The Mysterious Ways of ErbB2/HER2 Trafficking MEK inhibitors induce Akt activation and drug resistance by suppressing negative feedback ERK-mediated HER2 phosphorylation at Thr701.Septin oligomerization regulates persistent expression of ErbB2/HER2 in gastric cancer cells.ERBB2 oncogenicity: ERBIN helps to perform the job.A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells.Identification of an HSP90 modulated multi-step process for ERBB2 degradation in breast cancer cells.Tid1, CHIP and ErbB2 interactions and their prognostic implications for breast cancer patients.

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Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus.

http://www.wikidata.org/entity/Q30479942

description

2007 nî lūn-bûn

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2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հուլիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus.

@ast

Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus.

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type

label

Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus.

@ast

Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus.

@en

prefLabel

Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus.

@ast

Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus.

@en

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MBC.E07-01-0025

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Molecular Biology of the Cell

P1476

Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus

@en

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Anette M Hommelgaard

http://www.w3.org/2001/XMLSchema#string

Bo van Deurs

http://www.w3.org/2001/XMLSchema#string

Kirstine Roepstorff

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Malene M Kristensen

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Michael V Grandal

http://www.w3.org/2001/XMLSchema#string

Silas Bruun

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P2860

Ab-induced ectodomain shedding mediates hepatocyte growth factor receptor down-regulation and hampers biological activity

Improved prediction of signal peptides: SignalP 3.0

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

Cleavage of p75 neurotrophin receptor by alpha-secretase and gamma-secretase requires specific receptor domains.

Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90

gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

ErbB2 degradation mediated by the co-chaperone protein CHIP

Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers

HSP90 and the chaperoning of cancer

Rab7: a key to lysosome biogenesis

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3656-3666

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scholarly article

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10.1091/MBC.E07-01-0025

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9

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17626164

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1951740

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