Geldanamycin selectively targets the nascent form of ERBB3 for degradation

Geldanamycin selectively targets the nascent form of ERBB3 for degradation

Item
http://www.wikidata.org/entity/Q34427505
Targeting Hsp90 in urothelial carcinomaE3 ubiquitin ligases in ErbB receptor quantity control.High-throughput screening identifies aclacinomycin as a radiosensitizer of EGFR-mutant non-small cell lung cancerAnti-tumor activity of WK88-1, a novel geldanamycin derivative, in gefitinib-resistant non-small cell lung cancers with Met amplification.Targeting HER3 by interfering with its Sec61-mediated cotranslational insertion into the endoplasmic reticulum.HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death.A multicenter trial evaluating retaspimycin HCL (IPI-504) plus trastuzumab in patients with advanced or metastatic HER2-positive breast cancer.Phosphorylated and unphosphorylated serine 13 of CDC37 stabilize distinct interactions between its client and HSP90 binding domains.How Hsp90 and Cdc37 Lubricate Kinase Molecular Switches.Phosphorylation and ubiquitination of dynamin-related proteins (AtDRP3A/3B) synergically regulate mitochondrial proliferation during mitosis.In vitro analysis of putative cancer stem cell populations and chemosensitivity in the SW480 and SW620 colon cancer metastasis model.Combined BRAF and HSP90 Inhibition in Patients with Unresectable -Mutant Melanoma
P2860

Geldanamycin selectively targets the nascent form of ERBB3 for degradation

Item
http://www.wikidata.org/entity/Q34427505
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Geldanamycin selectively targets the nascent form of ERBB3 for degradation
@ast
Geldanamycin selectively targets the nascent form of ERBB3 for degradation
@en
Geldanamycin selectively targets the nascent form of ERBB3 for degradation
@nl
type
label
Geldanamycin selectively targets the nascent form of ERBB3 for degradation
@ast
Geldanamycin selectively targets the nascent form of ERBB3 for degradation
@en
Geldanamycin selectively targets the nascent form of ERBB3 for degradation
@nl
prefLabel
Geldanamycin selectively targets the nascent form of ERBB3 for degradation
@ast
Geldanamycin selectively targets the nascent form of ERBB3 for degradation
@en
Geldanamycin selectively targets the nascent form of ERBB3 for degradation
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Geldanamycin selectively targets the nascent form of ERBB3 for degradation
@en
P2093
P2860
P2888
P304
P31
P356
P433
P478
P577
P5875
P698
P932