Three-dimensional architecture of murine rod outer segments determined by cryoelectron tomography. - Wikidata - wikimedia - TriplyDB

Three-dimensional architecture of murine rod outer segments determined by cryoelectron tomography.

Three-dimensional architecture of murine rod outer segments determined by cryoelectron tomography.

http://www.wikidata.org/entity/Q30480467

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G-protein betagamma-complex is crucial for efficient signal amplification in vision Rod and cone visual pigments and phototransduction through pharmacological, genetic, and physiological approaches Integration of multiscale dendritic spine structure and function data into systems biology models Structural approaches to understanding retinal proteins needed for vision Chemistry of the retinoid (visual) cycle Three-dimensional architecture of the rod sensory cilium and its disruption in retinal neurodegeneration Proteomic identification of unique photoreceptor disc components reveals the presence of PRCD, a protein linked to retinal degeneration Membrane protein transport in photoreceptors: the function of PDEδ: the Proctor lecture CNTF and retina Activation of G protein-coupled receptors: beyond two-state models and tertiary conformational changes.Chemistry and biology of the initial steps in vision: the Friedenwald lecture.GARP2 accelerates retinal degeneration in rod cGMP-gated cation channel β-subunit knockout mice.Transport and localization of signaling proteins in ciliated cells Serial sectioning for examination of photoreceptor cell architecture by focused ion beam technology.Structure of cone photoreceptors.Diffusion of a soluble protein, photoactivatable GFP, through a sensory cilium Time-resolved fluorescence spectroscopy measures clustering and mobility of a G protein-coupled receptor opsin in live cell membranes Increased negative supercoiling of mtDNA in TOP1mt knockout mice and presence of topoisomerases IIα and IIβ in vertebrate mitochondria.All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis.Retinoids for treatment of retinal diseases Origins of cellular geometry.Shapes of discoid intracellular compartments with small relative volumes.The ATP-binding cassette transporter ABCA4: structural and functional properties and role in retinal disease.Comparative retinal morphology of the platypus.Rhodopsin expression level affects rod outer segment morphology and photoresponse kinetics Overexpression of rod photoreceptor glutamic acid rich protein 2 (GARP2) increases gain and slows recovery in mouse retina.Conservation of molecular interactions stabilizing bovine and mouse rhodopsin.Nanodomain organization of rhodopsin in native human and murine rod outer segment disc membranes.Serial block face-scanning electron microscopy: a method to study retinal degenerative phenotypes.Enzymatic properties and regulation of the native isozymes of retinal membrane guanylyl cyclase (RetGC) from mouse photoreceptors Expansion of first-in-class drug candidates that sequester toxic all-trans-retinal and prevent light-induced retinal degeneration.In situ visualization of protein interactions in sensory neurons: glutamic acid-rich proteins (GARPs) play differential roles for photoreceptor outer segment scaffolding Posttranslational modifications of the photoreceptor-specific ABC transporter ABCA4 Impact of reduced rhodopsin expression on the structure of rod outer segment disc membranes Steric volume exclusion sets soluble protein concentrations in photoreceptor sensory cilia.Structural and functional protein network analyses predict novel signaling functions for rhodopsin.Chemistry and biology of vision Rhodopsin Forms Nanodomains in Rod Outer Segment Disc Membranes of the Cold-Blooded Xenopus laevis.Three-dimensional organization of nascent rod outer segment disk membranes.Conformational dynamics of activation for the pentameric complex of dimeric G protein-coupled receptor and heterotrimeric G protein.

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P2860

Three-dimensional architecture of murine rod outer segments determined by cryoelectron tomography.

http://www.wikidata.org/entity/Q30480467

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2007 nî lūn-bûn

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2007 թուականի Մայիսին հրատարակուած գիտական յօդուած

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Three-dimensional architecture ...... ed by cryoelectron tomography.

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Paul S-H Park

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Stephan Nickell

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Wolfgang Baumeister

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P2860

Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis.

Interaction of glutamic-acid-rich proteins with the cGMP signalling pathway in rod photoreceptors

The cGMP-gated channel and related glutamic acid-rich proteins interact with peripherin-2 at the rim region of rod photoreceptor disc membranes

Retinal degeneration mutants in the mouse

Cryo-electron microscopy of vitrified specimens

Realizing the potential of electron cryo-microscopy

Expression and characterization of peripherin/rds-rom-1 complexes and mutants implicated in retinal degenerative diseases.

TOM software toolbox: acquisition and analysis for electron tomography.

The ultrastructure of the outer segments of rods and cones of the eye as revealed by the electron microscope.

Glutamic acid-rich proteins of rod photoreceptors are natively unfolded.

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Krzysztof Palczewski

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