Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices. - Wikidata - wikimedia - TriplyDB

Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices.

Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices.

http://www.wikidata.org/entity/Q30480500

about

Rac and Rho GTPases in cancer cell motility control Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage p53-cofactor JMY is a multifunctional actin nucleation factor Regulation of RhoA-dependent ROCKII activation by Shp2 The Diaphanous-related Formin FHOD1 associates with ROCK1 and promotes Src-dependent plasma membrane blebbing MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors Cell motility through plasma membrane blebbing Chemoresistance, cancer stem cells, and miRNA influences: the case for neuroblastoma Assembly, heterogeneity, and breaching of the basement membranes Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers Protein receptor-independent plasma membrane remodeling by HAMLET: a tumoricidal protein-lipid complex.Reduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells Tumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces.p53 Down regulates PDGF-induced formation of circular dorsal ruffles in rat aortic smooth muscle cells Initial steps of metastasis: cell invasion and endothelial transmigration A new role for microRNA-9 in human neural progenitor cells B-RAF regulation of Rnd3 participates in actin cytoskeletal and focal adhesion organization Rnd3 regulation of the actin cytoskeleton promotes melanoma migration and invasive outgrowth in three dimensions The tumor suppressor functions of p27(kip1) include control of the mesenchymal/amoeboid transition.Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease MMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferation.FilGAP, a Rho/Rho-associated protein kinase-regulated GTPase-activating protein for Rac, controls tumor cell migration Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells Loss of ERα induces amoeboid-like migration of breast cancer cells by downregulating vinculin.SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton Constructing Bayesian networks by integrating gene expression and copy number data identifies NLGN4Y as a novel regulator of prostate cancer progression.p53 in cell invasion, podosomes, and invadopodia Mesenchymal to amoeboid transition is associated with stem-like features of melanoma cells.The tumor suppressor role of miR-124 in osteosarcoma Arecoline induces HA22T/VGH hepatoma cells to undergo anoikis - involvement of STAT3 and RhoA activation p53 dependent centrosome clustering prevents multipolar mitosis in tetraploid cells Myosin VI is differentially regulated by DNA damage in p53- and cell type-dependent manners Multiple uses of basement membrane-like matrix (BME/Matrigel) in vitro and in vivo with cancer cells.Rho/ROCK signaling in motility and metastasis of gastric cancer The p53 isoform Δ133p53β promotes cancer stem cell potential.p53 in head and neck cancer: functional consequences and environmental implications of TP53 mutations.New plays in the p53 theater.Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited Function and regulation of Rnd proteins in cortical projection neuron migration OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo.

P2860

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P2860

Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices.

http://www.wikidata.org/entity/Q30480500

description

2007 nî lūn-bûn

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2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2007 թվականի հուլիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices.

@ast

Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices.

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type

label

Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices.

@ast

Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices.

@en

prefLabel

Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices.

@ast

Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices.

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Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices.

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Christelle Anguille

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Marion de Toledo

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Pierre Roux

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P2860

A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion

RhoE is a pro-survival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress

p53, the cellular gatekeeper for growth and division

Genomic analysis of metastasis reveals an essential role for RhoC

The complexity of p53 modulation: emerging patterns from divergent signals

Taking cell-matrix adhesions to the third dimension

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

A progression puzzle.

Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

The biology of cell locomotion within three-dimensional extracellular matrix.

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6230616

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