In vivo proliferation of postmitotic cochlear supporting cells by acute ablation of the retinoblastoma protein in neonatal mice
about
Sonic hedgehog initiates cochlear hair cell regeneration through downregulation of retinoblastoma protein.Conditional gene expression in the mouse inner ear using Cre-loxP.Where hearing starts: the development of the mammalian cochleaWnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea.Mammalian Cochlear Hair Cell Regeneration and Ribbon Synapse ReformationAuditory hair cell-specific deletion of p27Kip1 in postnatal mice promotes cell-autonomous generation of new hair cells and normal hearing.In vivo proliferative regeneration of balance hair cells in newborn mice.Postnatal development, maturation and aging in the mouse cochlea and their effects on hair cell regeneration.Generation of hair cells in neonatal mice by β-catenin overexpression in Lgr5-positive cochlear progenitors.Disrupting the interaction between retinoblastoma protein and Raf-1 leads to defects in progenitor cell proliferation and survival during early inner ear development.Cotransfection of Pax2 and Math1 promote in situ cochlear hair cell regeneration after neomycin insult.Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochleaUnderstanding the evolution and development of neurosensory transcription factors of the ear to enhance therapeutic translation.Selective ablation of pillar and deiters' cells severely affects cochlear postnatal development and hearing in mice.Active cochlear amplification is dependent on supporting cell gap junctionsEGFR signaling is required for regenerative proliferation in the cochlea: conservation in birds and mammalsFilling the silent void: genetic therapies for hearing impairment.Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochleaMYC gene delivery to adult mouse utricles stimulates proliferation of postmitotic supporting cells in vitro.Overlapping and distinct pRb pathways in the mammalian auditory and vestibular organs.Mature mice lacking Rbl2/p130 gene have supernumerary inner ear hair cells and supporting cells.Amplification mode differs along the length of the mouse cochlea as revealed by connexin 26 deletion from specific gap junctionsDNA damage signaling regulates age-dependent proliferative capacity of quiescent inner ear supporting cellsRestrictions in cell cycle progression of adult vestibular supporting cells in response to ectopic cyclin D1 expression.In vivo generation of immature inner hair cells in neonatal mouse cochleae by ectopic Atoh1 expressionp27(Kip1) is required to maintain proliferative quiescence in the adult cochlea and pituitary.In vivo Notch reactivation in differentiating cochlear hair cells induces Sox2 and Prox1 expression but does not disrupt hair cell maturation.Overactivation of Notch1 signaling induces ectopic hair cells in the mouse inner ear in an age-dependent manner.Age-dependent in vivo conversion of mouse cochlear pillar and Deiters' cells to immature hair cells by Atoh1 ectopic expressionRegulation of p27Kip1 by Sox2 maintains quiescence of inner pillar cells in the murine auditory sensory epithelium.Development of gene therapy for inner ear disease: Using bilateral vestibular hypofunction as a vehicle for translational research.Elastic force restricts growth of the murine utricle.Regeneration of hair cells in the mammalian vestibular system.Development and regeneration of vestibular hair cells in mammals.Cochlear hair cell regeneration after noise-induced hearing loss: Does regeneration follow development?Quantitative Analysis of Supporting Cell Subtype Labeling Among CreER Lines in the Neonatal Mouse Cochlea.Recent Advancements in the Regeneration of Auditory Hair Cells and Hearing RestorationPreservation of Cells of the Organ of Corti and Innervating Dendritic Processes Following Cochlear Implantation in the Human: an Immunohistochemical Study.Whole Mount Dissection and Immunofluorescence of the Adult Mouse Cochlea.Spontaneous Hair Cell Regeneration Is Prevented by Increased Notch Signaling in Supporting Cells.
P2860
Q24617669-A3FF836A-F408-4605-BFF4-5F6F79B07987Q26991845-A5802CF2-C747-4FB2-85D4-86C40AE9F458Q27027305-051DC8C0-6CDB-465C-A9E7-3A6F573F788AQ30360502-A714EE0B-6FCA-4F41-BC78-A878891BF445Q30365175-FA0DFA76-8428-4742-9C6A-59F3DFBBB041Q30411605-61B95F15-A81B-4E6B-A8C5-E65A1C7F7A6EQ30424024-859F04BF-083B-4142-BA9B-72BC30C0EFABQ30442295-2A052B16-7784-4410-958B-1D38B61BBE1DQ30442841-C888AF49-E031-454D-83A5-D80084A1E58EQ30444873-A41B6812-38C2-4D43-9E6D-65E172F11C1EQ30448163-2DD40A2E-C714-42FD-AF33-B749DE41C5DDQ30449542-73F370B0-4E62-4301-8CF0-9937EDCDD230Q30451361-825EBD29-8D47-4A5A-BB0B-9410061E6823Q30451949-9C5EA7B6-33AF-413C-A988-55CE5EB640DDQ30452999-5D6297AE-FDF1-4C9E-B5B4-14B848774C6CQ30457709-4A011661-C80A-459D-8FAF-E47EF87E4134Q30459235-C4AC3FAA-EC18-4481-8DD0-E113AAF84041Q30460671-03DEE4DA-6EB2-4CB2-AAFF-4E8EC3017CD8Q30461978-F3E41A90-DAAF-432A-B4A0-2576AA07FCD9Q30471443-F5F42484-90AB-46BF-8E1A-6772B747C14DQ30472107-A6B3EE61-5EF6-4BB6-906A-48DC54AD2B1AQ33899332-9E811F93-41AD-4504-A30B-5C6D383CD180Q33910490-7C6A8B65-7F54-4FBC-8C16-D0683F3DBB2AQ34071932-37C86C4E-0179-4155-8475-9487F224A8AFQ35107179-92E37A3D-2ECE-4D10-8456-9656DF4AEF84Q35592149-C18CC061-5548-4AAF-A64D-AA129B96A3E9Q35827931-02B65592-2CD7-4AC1-8C5B-C4B3498E3760Q35842582-93A6670E-20F8-4669-A1CB-889CD6A55092Q35986490-641DACCB-B51D-433A-866A-F8D42D642B41Q36187067-E74E70ED-224E-42CC-8850-1DA9E3BF52E2Q37830908-69F6549B-0225-4C92-9DC7-1B1303152654Q38662649-D92CC251-3195-4885-B2B9-0A36CABAC2C8Q38836733-5308DD99-DAE2-42A5-8811-0E8B872FAF9EQ39013579-34F82A24-7ADD-4EEB-AD25-A055CB3E165FQ39062528-C388CB39-51D9-44BB-91FD-3591DDDB8778Q39165751-DDB96192-74C8-4928-B49D-1330D5CDA4E5Q41170353-F55532CA-0804-4C9D-8E20-81B452029A3BQ47727741-7A618DBC-33D7-4E1D-859B-89AE293B3F3FQ52888491-529F21C7-59D4-422B-9235-AD59B8B1FE2DQ55311521-F7C2E861-9C6E-4416-AB2E-F04FF7FE4415
P2860
In vivo proliferation of postmitotic cochlear supporting cells by acute ablation of the retinoblastoma protein in neonatal mice
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
In vivo proliferation of postm ...... stoma protein in neonatal mice
@ast
In vivo proliferation of postm ...... stoma protein in neonatal mice
@en
type
label
In vivo proliferation of postm ...... stoma protein in neonatal mice
@ast
In vivo proliferation of postm ...... stoma protein in neonatal mice
@en
prefLabel
In vivo proliferation of postm ...... stoma protein in neonatal mice
@ast
In vivo proliferation of postm ...... stoma protein in neonatal mice
@en
P2093
P2860
P1476
In vivo proliferation of postm ...... stoma protein in neonatal mice
@en
P2093
Brandon C Cox
Marcus B Valentine
Tetsuji Yamashita
Thomas Weber
Zhiyong Liu
P2860
P304
P356
10.1523/JNEUROSCI.5989-09.2010
P407
P577
2010-04-01T00:00:00Z