LARG and mDia1 link Galpha12/13 to cell polarity and microtubule dynamics.
about
Interaction of the RAGE cytoplasmic domain with diaphanous-1 is required for ligand-stimulated cellular migration through activation of Rac1 and Cdc42Formins and microtubulesCell polarity signaling in the plasticity of cancer cell invasivenessFormins at a glanceThe mating-specific Galpha interacts with a kinesin-14 and regulates pheromone-induced nuclear migration in budding yeastFormin-like 2 drives amoeboid invasive cell motility downstream of RhoCBasidiomycete Mating Type Genes and Pheromone SignalingAn mDia1-INF2 formin activation cascade facilitated by IQGAP1 regulates stable microtubules in migrating cells.Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission.A role for planar cell polarity during early endoderm morphogenesis.CYLD regulates RhoA activity by modulating LARG ubiquitination.Activation of the Wnt/planar cell polarity pathway is required for pericyte recruitment during pulmonary angiogenesis.Cellular and molecular action of the mitogenic protein-deamidating toxin from Pasteurella multocida.The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling.PDZ-RhoGEF is essential for CXCR4-driven breast tumor cell motility through spatial regulation of RhoA.A conserved hydrophobic surface of the LARG pleckstrin homology domain is critical for RhoA activation in cells.Regulation of RhoGEF proteins by G12/13-coupled receptors.Role of G12 proteins in oncogenesis and metastasisEssential and nonredundant roles for Diaphanous formins in cortical microtubule capture and directed cell migration.Gα12 structural determinants of Hsp90 interaction are necessary for serum response element-mediated transcriptional activation.Recent insights into Pasteurella multocida toxin and other G-protein-modulating bacterial toxins.Tubulin, actin and heterotrimeric G proteins: coordination of signaling and structure.Pharmacological inhibition of actin assembly to target tumor cell motility.mDia2 and CXCL12/CXCR4 chemokine signaling intersect to drive tumor cell amoeboid morphological transitions.Inhibition of Diaphanous Formin Signaling In Vivo Impairs Cardiovascular Development and Alters Smooth Muscle Cell Phenotype.Formin-like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer.Expression of DIAPH1 is up-regulated in colorectal cancer and its down-regulation strongly reduces the metastatic capacity of colon carcinoma cells.Distinct roles for the actin nucleators Arp2/3 and hDia1 during NK-mediated cytotoxicity.A LARGe surprise links ATR and Rho.
P2860
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P2860
LARG and mDia1 link Galpha12/13 to cell polarity and microtubule dynamics.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
LARG and mDia1 link Galpha12/13 to cell polarity and microtubule dynamics.
@ast
LARG and mDia1 link Galpha12/13 to cell polarity and microtubule dynamics.
@en
type
label
LARG and mDia1 link Galpha12/13 to cell polarity and microtubule dynamics.
@ast
LARG and mDia1 link Galpha12/13 to cell polarity and microtubule dynamics.
@en
prefLabel
LARG and mDia1 link Galpha12/13 to cell polarity and microtubule dynamics.
@ast
LARG and mDia1 link Galpha12/13 to cell polarity and microtubule dynamics.
@en
P2860
P356
P1476
LARG and mDia1 link Galpha12/13 to cell polarity and microtubule dynamics.
@en
P2093
Helga Knieling
Polyxeni Goulimari
P2860
P356
10.1091/MBC.E06-11-1045
P577
2007-10-24T00:00:00Z