Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA
about
RhoA: a therapeutic target for chronic myeloid leukemiaDLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanismsPhysical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs)Myosin-X is a molecular motor that functions in filopodia formationAssociation of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activationRhoG signals in parallel with Rac1 and Cdc42The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARGIdentification of a novel sequence in PDZ-RhoGEF that mediates interaction with the actin cytoskeletonRho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapyRho GTPases in hematopoiesis and hemopathiesScambio, a novel guanine nucleotide exchange factor for RhoApproaches of targeting Rho GTPases in cancer drug discoveryRho GAPs and GEFs: controling switches in endothelial cell adhesionPTP-PEST couples membrane protrusion and tail retraction via VAV2 and p190RhoGAP.XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoCStructural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factorRHO-GTPases and cancerThe solution structure and dynamics of the DH-PH module of PDZRhoGEF in isolation and in complex with nucleotide-free RhoA.Rho GEF Lsc is required for normal polarization, migration, and adhesion of formyl-peptide-stimulated neutrophilsLARG and mDia1 link Galpha12/13 to cell polarity and microtubule dynamics.The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12.Influence of simulated microgravity on the activation of the small GTPase Rho involved in cytoskeletal formation--molecular cloning and sequencing of bovine leukemia-associated guanine nucleotide exchange factorHigh-throughput screening for small-molecule inhibitors of LARG-stimulated RhoA nucleotide binding via a novel fluorescence polarization assayStructure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors.The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signalsBinding of PDZ-RhoGEF to ATP-binding cassette transporter A1 (ABCA1) induces cholesterol efflux through RhoA activation and prevention of transporter degradation.Mdr1 gene expression and mutations in Ras proto-oncogenes in acute myeloid leukemia.Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK.Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA.The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling.GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.Conformational change upon ligand binding and dynamics of the PDZ domain from leukemia-associated Rho guanine nucleotide exchange factorA conserved hydrophobic surface of the LARG pleckstrin homology domain is critical for RhoA activation in cells.HspB1 silences translation of PDZ-RhoGEF by enhancing miR-20a and miR-128 expression to promote neurite extensionRho-guanine nucleotide exchange factors during development: Force is nothing without control.Inhibition and termination of physiological responses by GTPase activating proteins.Vav1 in hematologic neoplasms, a mini review.Rho GTPases modulate malignant transformation of tumor cells.Neuropeptide-stimulated cell migration in prostate cancer cells is mediated by RhoA kinase signaling and inhibited by neutral endopeptidase.Active RHOA favors retention of human hematopoietic stem/progenitor cells in their niche
P2860
Q21245760-D553A761-C583-43B4-9E2A-AF3FE944B25BQ24297480-D0F3C88B-FADA-4872-8895-15015D96034DQ24297673-993007BE-420A-4499-9CD2-280906C49249Q24299253-FDC27025-8EA6-4E4F-874F-FDE6B16EF6C8Q24307536-7B7D984D-AFC6-4804-AC74-B8A6A2E29587Q24310745-143E12DA-44C4-4F4F-8E1D-433753820F13Q24535768-3FF6BDA1-E902-41C4-85BD-8697B6CF2821Q24610248-E0612062-1A6F-49C4-BCF4-C74F181E3A64Q24631326-D57C3150-F387-4DDD-9507-40DA448C979AQ24652636-BF986AAE-0D3C-459A-BBDC-D76058611A49Q24806838-596D7C3C-36F8-49E2-88B8-2AD17F8E7C43Q26851300-B87DCE76-EF74-496B-BE73-AC42A738DF65Q26992281-E57E6D3F-615D-415F-8C0B-17DD18CB9724Q27312034-0B363CFA-A800-4B08-8DFE-276331ACF969Q28200973-47F82D63-C266-4A86-BD16-44E2D7020CE8Q28279079-00E6A51B-541A-4E44-B734-F3EA72A63DB8Q29616099-54A71884-76C8-41AD-A37D-96360C8F5A3EQ30434688-8592D280-F320-466B-8F20-E9DDA52591FCQ30479630-A7A3141E-544D-4B51-8534-226247839AA9Q30480988-FC42960A-838F-4DC7-B503-BB5BCE8D4D82Q30488952-AB51F28E-1CAF-4D96-AA4A-62F752D3B170Q33248082-0481EEF1-D028-4E9A-A1B3-27FAE8E3DDDDQ33406057-B4A8A281-5879-46F5-8C55-A7E365B2DBADQ33613391-BDBA6265-0D50-4BD4-BFDB-4710D93263E1Q33842285-7C2C3081-89F8-48AC-9C2A-FE03D7A92775Q33855331-709C477C-A7DC-4D2F-BFD8-0972881B9A73Q34155343-9C76A91E-3359-4284-8A86-42984A2290E9Q34200535-F3A58321-560C-4E93-80A8-CE51E50A15BBQ34280883-2F7BFE06-748A-4A98-AB91-02E42C69B1B4Q35499334-BFB9086C-ABCE-459C-AADB-E161782BF6FFQ36006905-358547E1-A2F0-4A17-9F37-F49486BBE169Q36662166-9BCB5ECF-32F0-4705-902E-6BA34AD77928Q37327655-0DC1918A-49BB-4BDE-A3BD-12C99CCFA542Q37494278-1CEDA467-7372-4210-8CDE-AE01FB9B169BQ37891679-CBE24847-91B0-4577-95FF-7221F1A5D720Q37980724-A0522249-FEA7-43D6-9E43-CB3BD73CA664Q37995197-CE93BE40-2397-481C-B731-E21DF06A903AQ38230951-A37A0AA8-BA44-4471-8F1C-3BA3B7BBAF8CQ40284709-F7BA7D70-8F77-4B1C-99BF-4FF9F0B21C87Q41902730-B4B562A5-3B6F-48E4-A570-AC7E4C7525C0
P2860
Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Leukemia-associated Rho guanin ...... ormation by activation of RhoA
@ast
Leukemia-associated Rho guanin ...... ormation by activation of RhoA
@en
Leukemia-associated Rho guanin ...... ormation by activation of RhoA
@nl
type
label
Leukemia-associated Rho guanin ...... ormation by activation of RhoA
@ast
Leukemia-associated Rho guanin ...... ormation by activation of RhoA
@en
Leukemia-associated Rho guanin ...... ormation by activation of RhoA
@nl
prefLabel
Leukemia-associated Rho guanin ...... ormation by activation of RhoA
@ast
Leukemia-associated Rho guanin ...... ormation by activation of RhoA
@en
Leukemia-associated Rho guanin ...... ormation by activation of RhoA
@nl
P2093
P2860
P356
P1476
Leukemia-associated Rho guanin ...... ormation by activation of RhoA
@en
P2093
B Becknell
G Marcucci
G W Reuther
M A Booden
M A Caligiuri
Q T Lambert
P2860
P304
P356
10.1074/JBC.M103565200
P407
P577
2001-07-20T00:00:00Z