Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice. - Wikidata - wikimedia - TriplyDB

Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice.

Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice.

http://www.wikidata.org/entity/Q30481572

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PI3K: An Attractive Candidate for the Central Integration of Metabolism and Reproduction Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility From observation to experimentation: leptin action in the mediobasal hypothalamus Recent advances in understanding leptin signaling and leptin resistance Age-Associated Weight Gain, Leptin, and SIRT1: A Possible Role for Hypothalamic SIRT1 in the Prevention of Weight Gain and Aging through Modulation of Leptin Sensitivity From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior Pacemaking kisspeptin neurons Central nervous control of energy and glucose balance: focus on the central melanocortin system Embryonic development of the hypothalamic feeding circuitry: Transcriptional, nutritional, and hormonal influences Hypothalamic control of brown adipose tissue thermogenesis Glucose level determines excitatory or inhibitory effects of adiponectin on arcuate POMC neuron activity and feeding.Magel2 is required for leptin-mediated depolarization of POMC neurons in the hypothalamic arcuate nucleus in mice SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity Prolyl carboxypeptidase regulates energy expenditure and the thyroid axis Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels Melanocortin neurons: Multiple routes to regulation of metabolism.Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis.Hormone and glucose signalling in POMC and AgRP neurons.Insulin and Leptin Signaling Interact in the Mouse Kiss1 Neuron during the Peripubertal Period.Shift in Kiss1 cell activity requires estrogen receptor α.Regulation of food intake and gonadotropin-releasing hormone/luteinizing hormone during lactation: role of insulin and leptin.Insulin excites anorexigenic proopiomelanocortin neurons via activation of canonical transient receptor potential channels.Central leptin receptor action and resistance in obesity.Leptin revisited: its mechanism of action and potential for treating diabetes.Cellular insulin resistance disrupts leptin-mediated control of neuronal signaling and transcription.Leptin receptor modulation of adiposity and fertility Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons.Enhanced hypothalamic leptin signaling in mice lacking dopamine D2 receptors.Insufficiency of Janus kinase 2-autonomous leptin receptor signals for most physiologic leptin actions Functional role of suppressor of cytokine signaling 3 upregulation in hypothalamic leptin resistance and long-term energy homeostasis.Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis.Neurobiology of inflammation-associated anorexia.Involvement of hypothalamic PI3K-STAT3 signalling in regulating appetite suppression mediated by amphetamine.A role of phosphodiesterase-3B pathway in mediating leptin action on proopiomelanocortin and neurotensin neurons in the hypothalamus.Leptin and insulin signaling in dopaminergic neurons: relationship between energy balance and reward system.Erk1/2 mediates leptin receptor signaling in the ventral tegmental area.Induction of leptin resistance by activation of cAMP-Epac signaling.Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice Leptin induces phosphorylation of neuronal nitric oxide synthase in defined hypothalamic neurons.The CNS glucagon-like peptide-2 receptor in the control of energy balance and glucose homeostasis

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P2860

Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice.

http://www.wikidata.org/entity/Q30481572

description

2008 nî lūn-bûn

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2008 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2008 թվականի մայիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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name

Acute effects of leptin requir ...... omelanocortin neurons in mice.

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Acute effects of leptin requir ...... omelanocortin neurons in mice.

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Acute effects of leptin requir ...... omelanocortin neurons in mice.

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Acute effects of leptin requir ...... omelanocortin neurons in mice.

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Acute effects of leptin requir ...... omelanocortin neurons in mice.

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Acute effects of leptin requir ...... omelanocortin neurons in mice.

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Journal of Clinical Investigation

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Acute effects of leptin requir ...... omelanocortin neurons in mice.

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Bradford B Lowell

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Chianping Ye

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Ji Luo

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Joel K Elmquist

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Nina Balthasar

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Roberto Coppari

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P2860

Positional cloning of the mouse obese gene and its human homologue

The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complex

Increased insulin sensitivity in mice lacking p85beta subunit of phosphoinositide 3-kinase

Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATP channel activation

Quantitative real-time PCR protocol for analysis of nuclear receptor signaling pathways.

Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism

Intracellular signalling. Key enzyme in leptin-induced anorexia

Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake

A phosphatidylinositol 3-kinase phosphodiesterase 3B-cyclic AMP pathway in hypothalamic action of leptin on feeding

STAT3 signalling is required for leptin regulation of energy balance but not reproduction

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10.1172/JCI32964

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5

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118

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Lewis C. Cantley

Kevin W. Williams

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2008-05-01T00:00:00Z

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18382766

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2276395

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