Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice - Wikidata - wikimedia - TriplyDB

Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice

Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice

http://www.wikidata.org/entity/Q34182689

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Skeletal muscle as a therapeutic target for delaying type 1 diabetic complications Recent Trends in Therapeutic Approaches for Diabetes Management: A Comprehensive Update Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals Physiology of leptin: energy homeostasis, neuroendocrine function and metabolism Nutrient-sensing mechanisms in the gut as therapeutic targets for diabetes Multifaceted interplay among mediators and regulators of intestinal glucose absorption: potential impacts on diabetes research and treatment Living without insulin: the role of leptin signaling in the hypothalamus The role of autonomic efferents and uncoupling protein 1 in the glucose-lowering effect of leptin therapy Leptin monotherapy rescues spermatogenesis in male Akita type 1 diabetic mice The effects of type 1 diabetes on the hypothalamic, pituitary and testes axis Leptin revisited: its mechanism of action and potential for treating diabetes.The role of leptin in glucose homeostasis.Cellular insulin resistance disrupts leptin-mediated control of neuronal signaling and transcription.Neurobiology of food intake in health and disease.Intracerebroventricular leptin infusion improves glucose homeostasis in lean type 2 diabetic MKR mice via hepatic vagal and non-vagal mechanisms.Islet-like cell aggregates generated from human adipose tissue derived stem cells ameliorate experimental diabetes in mice.Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover Novel regulatory mechanisms for generation of the soluble leptin receptor: implications for leptin action.Role of melanocortin signaling in neuroendocrine and metabolic actions of leptin in male rats with uncontrolled diabetes.Leptin receptor signaling in the hypothalamus regulates hepatic autonomic nerve activity via phosphatidylinositol 3-kinase and AMP-activated protein kinase Sixteen years and counting: an update on leptin in energy balance Spontaneously diabetic Ins2(+/Akita):apoE-deficient mice exhibit exaggerated hypercholesterolemia and atherosclerosis Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis Therapeutic impact of leptin on diabetes, diabetic complications, and longevity in insulin-deficient diabetic mice Leptin in human physiology and pathophysiology.Maternal diabetes compromises the organization of hypothalamic feeding circuits and impairs leptin sensitivity in offspring.Evidence That in Uncontrolled Diabetes, Hyperglucagonemia Is Required for Ketosis but Not for Increased Hepatic Glucose Production or Hyperglycemia.Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice Leptin therapy reverses hyperglycemia in mice with streptozotocin-induced diabetes, independent of hepatic leptin signaling.Minireview: CNS Mechanisms of Leptin Action.Adipose tissue biology and cardiomyopathy: translational implications.Effect of the co-administration of glucose with morphine on glucoregulatory hormones and causing of diabetes mellitus in rats Leptin, diabetes, and the brain Leptin therapy, insulin sensitivity, and glucose homeostasis.Regulatory role of leptin in glucose and lipid metabolism in skeletal muscle.Euglycemia Restoration by Central Leptin in Type 1 Diabetes Requires STAT3 Signaling but Not Fast-Acting Neurotransmitter Release.The role of leptin in the control of insulin-glucose axis.Extracellular signal-regulated kinase in the ventromedial hypothalamus mediates leptin-induced glucose uptake in red-type skeletal muscle.Leptin administration enhances islet transplant performance in diabetic mice.Leptin action in the ventromedial hypothalamic nucleus is sufficient, but not necessary, to normalize diabetic hyperglycemia.

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Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice

http://www.wikidata.org/entity/Q34182689

description

2010 nî lūn-bûn

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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Leptin therapy improves insuli ...... S-dependent mechanisms in mice

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Leptin therapy improves insuli ...... S-dependent mechanisms in mice

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Leptin therapy improves insuli ...... S-dependent mechanisms in mice

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type

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Leptin therapy improves insuli ...... S-dependent mechanisms in mice

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Leptin therapy improves insuli ...... S-dependent mechanisms in mice

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prefLabel

Leptin therapy improves insuli ...... S-dependent mechanisms in mice

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Leptin therapy improves insuli ...... S-dependent mechanisms in mice

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Leptin therapy improves insuli ...... S-dependent mechanisms in mice

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Proceedings of the National Academy of Sciences of the United States of America

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Leptin therapy improves insuli ...... S-dependent mechanisms in mice

@en

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Giorgio Ramadori

http://www.w3.org/2001/XMLSchema#string

Ichiro Sakata

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Jen-Chieh Chuang

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Roberto Coppari

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Teppei Fujikawa

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P2860

Intensive Diabetes Treatment and Cardiovascular Disease in Patients with Type 1 Diabetes

Leptin therapy in insulin-deficient type I diabetes

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Comparison of metabolic abnormalities in diabetes mellitus induced by streptozotocin or by alloxan

STZ transport and cytotoxicity. Specific enhancement in GLUT2-expressing cells

Genetics, pathogenesis and clinical interventions in type 1 diabetes

Type 1 diabetes

Insulin is a stronger inducer of insulin resistance than hyperglycemia in mice with type 1 diabetes mellitus (T1DM).

Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice.

Insulin resistance-related factors, but not glycemia, predict coronary artery disease in type 1 diabetes: 10-year follow-up data from the Pittsburgh Epidemiology of Diabetes Complications Study.

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17391-17396

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40

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107

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2010-09-20T00:00:00Z

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46381127

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20855609

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type-1 diabetes

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2951430

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