Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy.
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Potassium Channels and Human Epileptic Phenotypes: An Updated OverviewLimbic Encephalitis: Potential Impact of Adaptive Autoimmune Inflammation on Neuronal Circuits of the AmygdalaClinical and experimental studies of potentially pathogenic brain-directed autoantibodies: current knowledge and future directionsAutoimmune encephalitis updateThe search for circulating epilepsy biomarkersWhat non-neuronal mechanisms should be studied to understand epileptic seizures?LGI proteins in the nervous system.Complex network analysis of CA3 transcriptome reveals pathogenic and compensatory pathways in refractory temporal lobe epilepsyGlutamatergic neuron-targeted loss of LGI1 epilepsy gene results in seizuresNeuronal central nervous system syndromes probably mediated by autoantibodiesAutoimmune encephalitis in psychiatric institutions: current perspectivesSeizures and Epilepsies due to Channelopathies and Neurotransmitter Receptor Dysfunction: A Parallel between Genetic and Immune AspectsFaciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitisEtiology of a genetically complex seizure disorder in Celf4 mutant miceSocial learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinaseDysfunctional ADAM22 implicated in progressive encephalopathy with cortical atrophy and epilepsyAutoimmune encephalopathies.Autoantibodies to epilepsy-related LGI1 in limbic encephalitis neutralize LGI1-ADAM22 interaction and reduce synaptic AMPA receptorsK(+) channelepsy: progress in the neurobiology of potassium channels and epilepsy.Knockdown of zebrafish Lgi1a results in abnormal development, brain defects and a seizure-like behavioral phenotypeLoss of zebrafish lgi1b leads to hydrocephalus and sensitization to pentylenetetrazol induced seizure-like behavior.The temporal and spatial expression pattern of the LGI1 epilepsy predisposition gene during mouse embryonic cranial development.Electroclinical characterization of epileptic seizures in leucine-rich, glioma-inactivated 1-deficient mice.Advances in Autoimmune Epilepsy Associated with Antibodies, Their Potential Pathogenic Molecular Mechanisms, and Current Recommended ImmunotherapiesSimilarity of molecular phenotype between known epilepsy gene LGI1 and disease candidate gene LGI2.mTORC1 Is a Local, Postsynaptic Voltage Sensor Regulated by Positive and Negative Feedback Pathways.A computational model of the LGI1 protein suggests a common binding site for ADAM proteins.Neuronal Surface Autoantibodies in Neuropsychiatric Disorders: Are There Implications for Depression?LGI2 truncation causes a remitting focal epilepsy in dogs.Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case seriesIdentification of a novel idiopathic epilepsy locus in Belgian Shepherd dogs.Astroglial cradle in the life of the synapse.Autoimmune epilepsy: clinical characteristics and response to immunotherapyEncephalitis and AMPA receptor antibodies: Novel findings in a case series of 22 patients.Investigations of caspr2, an autoantigen of encephalitis and neuromyotoniaEssential roles of leucine-rich glioma inactivated 1 in the development of embryonic and postnatal cerebellum.Mutation of Elfn1 in mice causes seizures and hyperactivity.Encephalitis and antibodies to synaptic and neuronal cell surface proteins.Rare copy number variants are an important cause of epileptic encephalopathies.Identification of a common risk haplotype for canine idiopathic epilepsy in the ADAM23 gene.
P2860
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P2860
Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Disruption of LGI1-linked syna ...... tic transmission and epilepsy.
@ast
Disruption of LGI1-linked syna ...... tic transmission and epilepsy.
@en
type
label
Disruption of LGI1-linked syna ...... tic transmission and epilepsy.
@ast
Disruption of LGI1-linked syna ...... tic transmission and epilepsy.
@en
prefLabel
Disruption of LGI1-linked syna ...... tic transmission and epilepsy.
@ast
Disruption of LGI1-linked syna ...... tic transmission and epilepsy.
@en
P2093
P2860
P356
P1476
Disruption of LGI1-linked syna ...... tic transmission and epilepsy.
@en
P2093
Atsushi Watanabe
Kathryn L Lovero
Katsuhiko Tabuchi
Masaki Fukata
Norihiko Yokoi
Roger A Nicoll
Ryuichi Shigemoto
Tsuyoshi Iwanaga
Yuko Fukata
P2860
P304
P356
10.1073/PNAS.0914537107
P407
P577
2010-02-02T00:00:00Z