Single VS ribozyme molecules reveal dynamic and hierarchical folding toward catalysis.
about
Single molecule fluorescence approaches shed light on intracellular RNAsSingle transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structureNondenaturing purification of co-transcriptionally folded RNA avoids common folding heterogeneityConformational dynamics of single pre-mRNA molecules during in vitro splicing.Biased Brownian ratcheting leads to pre-mRNA remodeling and capture prior to first-step splicing.Multivector fluorescence analysis of the xpt guanine riboswitch aptamer domain and the conformational role of guanineMetal ions: supporting actors in the playbook of small ribozymes.RNA reactions one molecule at a timeSingle-molecule tools for enzymology, structural biology, systems biology and nanotechnology: an update.Metal-ion-dependent folding of a uranyl-specific DNAzyme: insight into function from fluorescence resonance energy transfer studies.A rugged free energy landscape separates multiple functional RNA folds throughout denaturationLeakage and slow allostery limit performance of single drug-sensing aptazyme molecules based on the hammerhead ribozyme.Conformational change in the Bacillus subtilis RNase P holoenzyme--pre-tRNA complex enhances substrate affinity and limits cleavage rateSingle-Molecule Fluorescence Studies of RNA: A Decade's Progress.Single-molecule studies of riboswitch folding.Insights into RNA structure and dynamics from recent NMR and X-ray studies of the Neurospora Varkud satellite ribozyme.Single-molecule Förster resonance energy transfer studies of RNA structure, dynamics and function.Assembly and dynamics of the U4/U6 di-snRNP by single-molecule FRET.Long-range tertiary interactions in single hammerhead ribozymes bias motional sampling toward catalytically active conformationsAnalysis of complex single-molecule FRET time trajectories.Native purification and labeling of RNA for single molecule fluorescence studiesThe shape-shifting quasispecies of RNA: one sequence, many functional foldsThe NMR structure of the II-III-VI three-way junction from the Neurospora VS ribozyme reveals a critical tertiary interaction and provides new insights into the global ribozyme structure.The Small Ribozymes: Common and Diverse Features Observed through the FRET Lens.Additional roles of a peripheral loop-loop interaction in the Neurospora VS ribozyme.Life under the Microscope: Single-Molecule Fluorescence Highlights the RNA World.Rational design of DNA-actuated enzyme nanoreactors guided by single molecule analysis.
P2860
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P2860
Single VS ribozyme molecules reveal dynamic and hierarchical folding toward catalysis.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Single VS ribozyme molecules reveal dynamic and hierarchical folding toward catalysis.
@ast
Single VS ribozyme molecules reveal dynamic and hierarchical folding toward catalysis.
@en
type
label
Single VS ribozyme molecules reveal dynamic and hierarchical folding toward catalysis.
@ast
Single VS ribozyme molecules reveal dynamic and hierarchical folding toward catalysis.
@en
prefLabel
Single VS ribozyme molecules reveal dynamic and hierarchical folding toward catalysis.
@ast
Single VS ribozyme molecules reveal dynamic and hierarchical folding toward catalysis.
@en
P2093
P2860
P1476
Single VS ribozyme molecules reveal dynamic and hierarchical folding toward catalysis
@en
P2093
Dominic Jaikaran
Miguel J B Pereira
Richard A Collins
Shawna L Hiley
P2860
P304
P356
10.1016/J.JMB.2008.07.020
P407
P577
2008-07-16T00:00:00Z