ADP-ribosylation factor 6 regulates insulin secretion through plasma membrane phosphatidylinositol 4,5-bisphosphate
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GEP100/BRAG2: activator of ADP-ribosylation factor 6 for regulation of cell adhesion and actin cytoskeleton via E-cadherin and alpha-cateninPhosphoinositides: Key modulators of energy metabolismADP ribosylation factor 6 (ARF6) promotes acrosomal exocytosis by modulating lipid turnover and Rab3A activation.Cytoskeletal dependence of insulin granule movement dynamics in INS-1 beta-cells in response to glucoseRegulatory roles for Tiam1, a guanine nucleotide exchange factor for Rac1, in glucose-stimulated insulin secretion in pancreatic beta-cellsRal-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signallingThe GTPase RalA regulates different steps of the secretory process in pancreatic beta-cells.YES, a Src family kinase, is a proximal glucose-specific activator of cell division cycle control protein 42 (Cdc42) in pancreatic islet β cellsSmall G proteins in islet beta-cell function.Insulin-stimulated plasma membrane fusion of Glut4 glucose transporter-containing vesicles is regulated by phospholipase D1.Regulation of insulin secretion by phosphatidylinositol-4,5-bisphosphate.Phosphatidylinositol phosphate kinase type I gamma regulates dynamics of large dense-core vesicle fusion.An effector domain mutant of Arf6 implicates phospholipase D in endosomal membrane recycling.Membrane phosphoinositides control insulin secretion through their effects on ATP-sensitive K+ channel activity.Phosphatidylinositol-4-phosphate-5-kinase alpha deficiency alters dynamics of glucose-stimulated insulin release to improve glucohomeostasis and decrease obesity in mice.Impaired insulin secretion in transgenic mice over-expressing calpastatin in pancreatic β-cellsProtein prenylation in glucose-induced insulin secretion from the pancreatic islet beta cell: a perspective.Friendly, and not so friendly, roles of Rac1 in islet β-cell function: lessons learnt from pharmacological and molecular biological approachesArf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 β-cells and rat islets.EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells.Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet.Emerging roles for protein histidine phosphorylation in cellular signal transduction: lessons from the islet beta-cell.VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells.Imaging phosphoinositide dynamics using GFP-tagged protein domains.An integrative systems genetics approach reveals potential causal genes and pathways related to obesity.Insulin vesicle release: walk, kiss, pause ... then run.Supervised membrane swimming: small G-protein lifeguards regulate PIPK signalling and monitor intracellular PtdIns(4,5)P2 pools.Glucose-stimulated Cdc42 signaling is essential for the second phase of insulin secretionPhospholipase D signaling: orchestration by PIP2 and small GTPases.Clathrin-independent endocytosis: a unique platform for cell signaling and PM remodelingNm23-H1 regulates glucose-stimulated insulin secretion in pancreatic β-cells via Arf6-Rac1 signaling axis.A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell.Regulation of PIP5K activity by Arf6 and its physiological significance.Role of PI(4,5)P(2) in vesicle exocytosis and membrane fusion.Arf6 regulates tumour angiogenesis and growth through HGF-induced endothelial β1 integrin recycling.Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and MiceSomatostatin receptors signal through EFA6A-ARF6 to activate phospholipase D in clonal beta-cells.Optimal elevation of β-cell 11β-hydroxysteroid dehydrogenase type 1 is a compensatory mechanism that prevents high-fat diet-induced β-cell failure.Ultrastructural Localization of Endogenous Exchange Factor for ARF6 in Adrenocortical Cells In Situ of Mice.Phosphatidylinositol 4,5-bisphosphate regulates adipocyte actin dynamics and GLUT4 vesicle recycling.
P2860
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P2860
ADP-ribosylation factor 6 regulates insulin secretion through plasma membrane phosphatidylinositol 4,5-bisphosphate
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
ADP-ribosylation factor 6 regu ...... tidylinositol 4,5-bisphosphate
@ast
ADP-ribosylation factor 6 regu ...... tidylinositol 4,5-bisphosphate
@en
type
label
ADP-ribosylation factor 6 regu ...... tidylinositol 4,5-bisphosphate
@ast
ADP-ribosylation factor 6 regu ...... tidylinositol 4,5-bisphosphate
@en
prefLabel
ADP-ribosylation factor 6 regu ...... tidylinositol 4,5-bisphosphate
@ast
ADP-ribosylation factor 6 regu ...... tidylinositol 4,5-bisphosphate
@en
P2860
P356
P1476
ADP-ribosylation factor 6 regu ...... tidylinositol 4,5-bisphosphate
@en
P2093
John T R Lawrence
P2860
P304
13320-13325
P356
10.1073/PNAS.2232129100
P407
P577
2003-10-29T00:00:00Z