Membrane phosphoinositides control insulin secretion through their effects on ATP-sensitive K+ channel activity.
about
A novel KCNJ11 mutation associated with congenital hyperinsulinism reduces the intrinsic open probability of beta-cell ATP-sensitive potassium channelsRole of Hsp90 in biogenesis of the beta-cell ATP-sensitive potassium channel complexCholesterol regulates glucose-stimulated insulin secretion through phosphatidylinositol 4,5-bisphosphate.A role of the sulfonylurea receptor 1 in endocytic trafficking of ATP-sensitive potassium channels.Taming membranes: functional immobilization of biological membranes in hydrogels.Phosphatidylinositol-4-phosphate-5-kinase alpha deficiency alters dynamics of glucose-stimulated insulin release to improve glucohomeostasis and decrease obesity in mice.ATP modulates interaction of syntaxin-1A with sulfonylurea receptor 1 to regulate pancreatic beta-cell KATP channelsSyntaxin 1A regulates surface expression of beta-cell ATP-sensitive potassium channels.Structurally distinct ligands rescue biogenesis defects of the KATP channel complex via a converging mechanism.Role of Derlin-1 protein in proteostasis regulation of ATP-sensitive potassium channels.Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational AnalysisCongenital hyperinsulinism associated ABCC8 mutations that cause defective trafficking of ATP-sensitive K+ channels: identification and rescueCarbamazepine as a novel small molecule corrector of trafficking-impaired ATP-sensitive potassium channels identified in congenital hyperinsulinism.Pharmacological rescue of trafficking-impaired ATP-sensitive potassium channels.Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating.Cholesterol-enriched membrane rafts and insulin secretion.Phosphatidylinositol 4,5-biphosphate (PIP2) modulates interaction of syntaxin-1A with sulfonylurea receptor 1 to regulate pancreatic β-cell ATP-sensitive potassium channels.Destabilization of ATP-sensitive potassium channel activity by novel KCNJ11 mutations identified in congenital hyperinsulinism.Molecular mechanisms of muscarinic acetylcholine receptor-stimulated increase in cytosolic free Ca(2+) concentration and ERK1/2 activation in the MIN6 pancreatic β-cell line.Prostatic acid phosphatase reduces thermal sensitivity and chronic pain sensitization by depleting phosphatidylinositol 4,5-bisphosphate.Sulfonylurea receptor 1 mutations that cause opposite insulin secretion defects with chemical chaperone exposure.Anti-diabetic drug binding site in a mammalian KATP channel revealed by Cryo-EM.
P2860
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P2860
Membrane phosphoinositides control insulin secretion through their effects on ATP-sensitive K+ channel activity.
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Membrane phosphoinositides con ...... sensitive K+ channel activity.
@ast
Membrane phosphoinositides con ...... sensitive K+ channel activity.
@en
Membrane phosphoinositides con ...... sensitive K+ channel activity.
@nl
type
label
Membrane phosphoinositides con ...... sensitive K+ channel activity.
@ast
Membrane phosphoinositides con ...... sensitive K+ channel activity.
@en
Membrane phosphoinositides con ...... sensitive K+ channel activity.
@nl
prefLabel
Membrane phosphoinositides con ...... sensitive K+ channel activity.
@ast
Membrane phosphoinositides con ...... sensitive K+ channel activity.
@en
Membrane phosphoinositides con ...... sensitive K+ channel activity.
@nl
P2093
P2860
P1433
P1476
Membrane phosphoinositides con ...... sensitive K+ channel activity.
@en
P2093
Chia-Wei Lin
Feifei Yan
Satoko Shimamura
Show-Ling Shyng
P2860
P304
P356
10.2337/DIABETES.54.10.2852
P407
P577
2005-10-01T00:00:00Z