Dual role of Cdc42 in spindle orientation control of adherent cells
about
The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis.How PI3K-derived lipids control cell divisionScribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary glandPak1 regulates the orientation of apical polarization and lumen formation by distinct pathwaysLGN regulates mitotic spindle orientation during epithelial morphogenesis.Ric-8A and Gi alpha recruit LGN, NuMA, and dynein to the cell cortex to help orient the mitotic spindle.Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesisABL1 regulates spindle orientation in adherent cells and mammalian skin.Dynein light chain 1 and a spindle-associated adaptor promote dynein asymmetry and spindle orientation.Automated tracking of mitotic spindle pole positions shows that LGN is required for spindle rotation but not orientation maintenance.Astral microtubules control redistribution of dynein at the cell cortex to facilitate spindle positioning.The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity.Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice.aPKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation.JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis.Cell Fate Decision Making through Oriented Cell Division.Cilia, Wnt signaling, and the cytoskeletonFormin-mediated actin polymerization cooperates with Mushroom body defect (Mud)-Dynein during Frizzled-Dishevelled spindle orientation.Rab14 specifies the apical membrane through Arf6-mediated regulation of lipid domains and Cdc42.Involvement of microRNA-224 in cell proliferation, migration, invasion, and anti-apoptosis in hepatocellular carcinoma.Prostate-derived sterile 20-like kinases (PSKs/TAOKs) are activated in mitosis and contribute to mitotic cell rounding and spindle positioning.Cell adhesion molecule control of planar spindle orientation.Mitosis can drive cell cannibalism through entosis.The secret life of kinases: functions beyond catalysisEct2/Pbl acts via Rho and polarity proteins to direct the assembly of an isotropic actomyosin cortex upon mitotic entry.Palladin is a novel microtubule-associated protein responsible for spindle orientation.PCTK1 regulates integrin-dependent spindle orientation via protein kinase A regulatory subunit KAP0 and myosin X.Rescue of glandular dysmorphogenesis in PTEN-deficient colorectal cancer epithelium by PPARγ-targeted therapy.Mitotic spindle orientation: JAM-A can fix it.Podocalyxin promotes proliferation and survival in mature B-cell non-Hodgkin lymphoma cells.Junctional Adhesion Molecules (JAMs): Cell Adhesion Receptors With Pleiotropic Functions in Cell Physiology and Development.P21-activated kinase 4 (PAK4) is required for metaphase spindle positioning and anchoring.MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progression.
P2860
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P2860
Dual role of Cdc42 in spindle orientation control of adherent cells
description
2009 nî lūn-bûn
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2009 թուականի Մարտին հրատարակուած գիտական յօդուած
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2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年論文
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2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
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2009年论文
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name
Dual role of Cdc42 in spindle orientation control of adherent cells
@ast
Dual role of Cdc42 in spindle orientation control of adherent cells
@en
type
label
Dual role of Cdc42 in spindle orientation control of adherent cells
@ast
Dual role of Cdc42 in spindle orientation control of adherent cells
@en
prefLabel
Dual role of Cdc42 in spindle orientation control of adherent cells
@ast
Dual role of Cdc42 in spindle orientation control of adherent cells
@en
P2093
P2860
P356
P1476
Dual role of Cdc42 in spindle orientation control of adherent cells
@en
P2093
Eisuke Nishida
Fumiko Toyoshima
Masaru Mitsushima
P2860
P304
P356
10.1128/MCB.01713-08
P407
P577
2009-03-09T00:00:00Z