Profilin 1 is required for abscission during late cytokinesis of chondrocytes
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Molecular insights on context-specific role of profilin-1 in cell migrationProfilin-1 overexpression inhibits proliferation of MDA-MB-231 breast cancer cells partly through p27kip1 upregulation.Preserved morphology and physiology of excitatory synapses in profilin1-deficient mice.Protein phosphatase 1 dephosphorylates profilin-1 at Ser-137Role of subchondral bone during early-stage experimental TMJ osteoarthritis.Subcellular localization and Ser-137 phosphorylation regulate tumor-suppressive activity of profilin-1.Parallel up-regulation of the profilin gene family following independent domestication of diploid and allopolyploid cotton (Gossypium).Matrix compliance and the regulation of cytokinesis.NAC1 is an actin-binding protein that is essential for effective cytokinesis in cancer cells.BRCA1 deficiency in ovarian cancer is associated with alteration in expression of several key regulators of cell motility - A proteomics study.eNOS S-nitrosylates β-actin on Cys374 and regulates PKC-θ at the immune synapse by impairing actin binding to profilin-1.Profilin-1 downregulation has contrasting effects on early vs late steps of breast cancer metastasisBeta1 integrin deficiency results in multiple abnormalities of the knee joint.Profilin 1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrowProfilin1 is expressed in osteocytes and regulates cell shape and migration.Profilin1 biology and its mutation, actin(g) in disease.Profilin1 regulates sternum development and endochondral bone formation.Integrin signaling via FAK-Src controls cytokinetic abscission by decelerating PLK1 degradation and subsequent recruitment of CEP55 at the midbody.Profilin1 is required for glial cell adhesion and radial migration of cerebellar granule neurons.Profilin1 activity in cerebellar granule neurons is required for radial migration in vivo.Integrin-linked kinase controls microtubule dynamics required for plasma membrane targeting of caveolaeRole of the actin-binding protein profilin1 in radial migration and glial cell adhesion of granule neurons in the cerebellum.A loss of profilin-1 in late-stage oral squamous cell carcinoma.The neuronal and actin commitment: Why do neurons need rings?Structure-based virtual screening identifies small molecule inhibitor of the profilin1-actin interaction.A balanced level of profilin-1 promotes stemness and tumor-initiating potential of breast cancer cells.Pharmacological intervention of MKL/SRF signaling by CCG-1423 impedes endothelial cell migration and angiogenesis.[Temporal regulation of abscission, the last step of cell division].Don't throw out the sympatric speciation with the crater lake water: fine-scale investigation of introgression provides equivocal support for causal role of secondary gene flow in one of the clearest examples of sympatric speciationProteomic analysis of rat serum revealed the effects of chronic sleep deprivation on metabolic, cardiovascular and nervous system
P2860
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P2860
Profilin 1 is required for abscission during late cytokinesis of chondrocytes
description
2009 nî lūn-bûn
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2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
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2009年の論文
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2009年論文
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2009年論文
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2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
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name
Profilin 1 is required for abscission during late cytokinesis of chondrocytes
@ast
Profilin 1 is required for abscission during late cytokinesis of chondrocytes
@en
type
label
Profilin 1 is required for abscission during late cytokinesis of chondrocytes
@ast
Profilin 1 is required for abscission during late cytokinesis of chondrocytes
@en
prefLabel
Profilin 1 is required for abscission during late cytokinesis of chondrocytes
@ast
Profilin 1 is required for abscission during late cytokinesis of chondrocytes
@en
P2093
P2860
P356
P1433
P1476
Profilin 1 is required for abscission during late cytokinesis of chondrocytes
@en
P2093
Alejandro Berna
Alexander Pfeifer
Attila Aszódi
Attila Braun
Mercedes Costell
Nadav Elad
Ohad Medalia
Ralph T Böttcher
Reiner Wimmer
Sebastian Wiesner
P2860
P304
P356
10.1038/EMBOJ.2009.58
P407
P577
2009-03-05T00:00:00Z