PICK1 uncoupling from mGluR7a causes absence-like seizures. - Wikidata - wikimedia - TriplyDB

PICK1 uncoupling from mGluR7a causes absence-like seizures.

PICK1 uncoupling from mGluR7a causes absence-like seizures.

http://www.wikidata.org/entity/Q30491105

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Let's go bananas: revisiting the endocytic BAR code Role of PDZ proteins in regulating trafficking, signaling, and function of GPCRs: means, motif, and opportunity Phasic and Tonic mGlu7 Receptor Activity Modulates the Thalamocortical Network Biomimetic divalent ligands for the acute disruption of synaptic AMPAR stabilization Metabotropic Glutamate Receptor 7 (mGluR7) as a Target for the Treatment of Psychostimulant Dependence Disrupting 5-HT(2A) receptor/PDZ protein interactions reduces hyperalgesia and enhances SSRI efficacy in neuropathic pain Temporal and topographic alterations in expression of the alpha3 isoform of Na+, K(+)-ATPase in the rat freeze lesion model of microgyria and epileptogenesis Metabotropic glutamate receptors: from the workbench to the bedside.Context-dependent pharmacology exhibited by negative allosteric modulators of metabotropic glutamate receptor 7 Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD.Role of the axonal initial segment in psychiatric disorders: function, dysfunction, and intervention Rewiring of PDZ domain-ligand interaction network contributed to eukaryotic evolution.Metabotropic glutamate receptors in the thalamocortical network: strategic targets for the treatment of absence epilepsy.Neurochemical and behavioral features in genetic absence epilepsy and in acutely induced absence seizures.Membrane-permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release.Neuroprotection against neonatal hypoxia/ischemia-induced cerebral cell death by prevention of calpain-mediated mGluR1alpha truncation.Therapeutic promise and principles: metabotropic glutamate receptors Protein-protein interactions as therapeutic targets in neuropsychopharmacology.Modulation of short-term plasticity in the corticothalamic circuit by group III metabotropic glutamate receptors.Metabotropic glutamate receptors: physiology, pharmacology, and disease.Overview of glutamatergic neurotransmission in the nervous system.Protein interacting with C kinase and neurological disorders.Progress toward advanced understanding of metabotropic glutamate receptors: structure, signaling and therapeutic indications Metabotropic Glutamate Receptor 7: From Synaptic Function to Therapeutic Implications.The scaffold protein NHERF2 determines the coupling of P2Y1 nucleotide and mGluR5 glutamate receptor to different ion channels in neurons.Elfn1 recruits presynaptic mGluR7 in trans and its loss results in seizures.The binding affinities of proteins interacting with the PDZ domain of PICK1.Metabotropic glutamate receptor trafficking.PICK1 expression in reactive astrocytes within the spinal cord of amyotrophic lateral sclerosis (ALS) rats.Metabotropic Glutamate Receptor 7: A New Therapeutic Target in Neurodevelopmental Disorders

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P2860

PICK1 uncoupling from mGluR7a causes absence-like seizures.

http://www.wikidata.org/entity/Q30491105

description

2008 nî lūn-bûn

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2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հուլիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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name

PICK1 uncoupling from mGluR7a causes absence-like seizures.

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PICK1 uncoupling from mGluR7a causes absence-like seizures.

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type

label

PICK1 uncoupling from mGluR7a causes absence-like seizures.

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PICK1 uncoupling from mGluR7a causes absence-like seizures.

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PICK1 uncoupling from mGluR7a causes absence-like seizures.

@ast

PICK1 uncoupling from mGluR7a causes absence-like seizures.

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Nature Neuroscience

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PICK1 uncoupling from mGluR7a causes absence-like seizures.

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Astrid Scheschonka

http://www.w3.org/2001/XMLSchema#string

Chuansheng Zhang

http://www.w3.org/2001/XMLSchema#string

Federica Bertaso

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Frédéric de Bock

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Heinrich Betz

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Laurent Fagni

http://www.w3.org/2001/XMLSchema#string

Mireille Lerner-Natoli

http://www.w3.org/2001/XMLSchema#string

Philippe Marin

http://www.w3.org/2001/XMLSchema#string

Pierre Fontanaud

http://www.w3.org/2001/XMLSchema#string

Richard L Huganir

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P2860

PICK1 is required for the control of synaptic transmission by the metabotropic glutamate receptor 7

Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms

The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs

(R,S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo

Mutations in high-voltage-activated calcium channel genes stimulate low-voltage-activated currents in mouse thalamic relay neurons

Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7

High level of mGluR7 in the presynaptic active zones of select populations of GABAergic terminals innervating interneurons in the rat hippocampus

In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis

PICK1 interacts with and regulates PKC phosphorylation of mGLUR7

Childhood absence epilepsy: genes, channels, neurons and networks.

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10.1038/NN.2142

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